How Effective Is Pep After Exposure

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Get the Facts

Treatment After Exposure to HIV

For serious exposures, the U.S. Public Health Service recommends using a combination of three approved ARVs for four weeks. For less serious exposure, the guidelines recommend four weeks of treatment with two drugs: zidovudine (Retrovir, AZT) and lamivudine (Epivir, 3TC). In January 2001, the Centers for Disease Control warned against using nevirapine (Viramune) for PEP because of the risk of liver damage. See Fact Sheet 431 for more...

Ask the Experts

How effective is PEP started 60 hours after exposure?

I had bareback sex with a man who I found out was HIV positive, but he said he had a low viral load and high counts of CD-4. I don't know whether to trust this though. I put off getting PEP because I was too scared I'd be judged by my...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Hello and thanks for your post.Just because you don't have any side effects doesn't mean that the medications that you're taking aren't working. Indeed, many persons who take HIV meds (including those who are taking them for... Read more »

HCW exposure (OCCUPATIONAL EXPOSURE, PEP)

Dear Dr., Quick question: A HCW had a needlestick injury involving a pt of known HIV/HepC status and was then treated with Combivir/Tenofovir for 4 weeks for this exposure. She has had an 8wk ELISA (neg) (4wks after completion of PEP), and a 9wk...

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation

Hello RT,This is one of the reasons I feel strongly that anyone who has sustained an HIV exposure significant enough to warrant a course of PEP should be followed by an HIV specialist. HIV specialists are best trained to evaluate and document a... Read more »

EMERGENCY ROOM DIDN'T KNOW ABOUT PEP! (NEW YORK STATES PEP TOOL) (TOOL TO OFFER FAST HELP FOR HIV EXPOSURE, 2009)

Dr. Bob,I live in New York (the state not the city). I had a significant HIV exposure and went to an ER. The doc and staff never heard of PEP. What's up with that?Zorro...

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation

Hello,We've heard many similar stories from across the country. New York State is doing its part to remedy this unconscionable situation (see below). I'm hopeful all other states won't be far behind.Dr. BobTool to Offer Fast Help for... Read more »

Exposure of HIV and PEP treatment

i need to know the time of exposure of HIV virus that one is need to go to PEP treatment...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

PEP is only effective if started within 72 hours of the HIV exposure.BY... Read more »

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Connect With Others

Post-Exposure Prophylaxis (PEP) - Help

Posted by MF2010

Hi all,

I've been exposed to HIV in the beginning of this month.
My condom completely broke and i had sex for a couple of minutes completely exposed. I suspect my partner was HIV infected.

Went straight to the hospital and started Post-Exposure... Read more »

Known Exposure(?); PEP; HEP C "cured"; Home Access

Posted by login123

What a roller coaster this has been. In November, I started having sex with someone who was HIV + and "cured" of Hep C for several years (5+). I saw his medical records. With regards to HIV, he had an undetectable viral load <20 for years and was... Read more »

6weeks/post exposure/pep meds result

Posted by justagirl72

So my employee health nurse called to let me know that my test for HIV and Hep C were Negative..yay..but I know its not conclusive. my HepB was reactive but I have an immunity from a vaccine..so now its back to the waiting game and counting the... Read more »

PEP related query

Posted by TODude, 1 Reply

Hey everyone,

So I had a possible exposure to HIV on Sunday Jan 20th. I have been on PEP since monday the 21st (started 30-36 hours PE). My question is - should I have started PEP in the first place? and is Combivir alone an effective PEP regimen?

Ba... Read more »

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