How Does Hiv Replicate

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Articles

HIV Found to Replicate Outside CD4 Cells; Discovery Gives Insight Into HIV-related Dementia

In an intriguing new study published last week in PLoS Pathogens , researchers discovered the first solid proof that HIV can replicate itself in cell types other than CD4 cells. The finding potentially opens an important window on our understanding... Read more »

U.S. Centers for Disease Control and Prevention

University of Pittsburgh Team Finds "Achilles Heel" of Key HIV Replication Protein

University of Pittsburgh School of Medicine researchers report they have developed a way to track -- and perhaps block -- the activity of Nef, an HIV protein that is critical to HIV replication. According to researcher Thomas Smithgall, Ph.D., the... Read more »

Suppression of Human Protein Reduces HIV's Ability to Enter T Cells, Replicate, Study Finds

Researchers have found that suppressing the human protein ITK in CD4+ T cells reduces HIV's ability to enter the cells and replicate, according to an NIH study published Monday in the Proceedings of the National Academy of Sciences , Reuters ... Read more »

Ask the Experts

Replication Capacity and HIV disease progression

I recently seroconverted two months ago. Shortly afterwards, the HIV clinic that I being supervised at did a resistance test. Gladly I was found to have no drug resistances, however my Viral Replication Capacity was found to be above average at...

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine

The replication capacity assay has not been shown to be definitively predictive of disease progression. Your RC is in the normal range, and reflects a wild type virus, that is, one that does not have any resistance mutations. Your don't... Read more »

Replication mechanism of HIV

Dear Doctor Holodniy,I'll like to ask what is the mechanism of HIV's replication like? Specifically, for the HIV reverse transcriptase, does it convert single strand RNA template to a single strand DNA? If so, how does this single strand...

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine

The HIV reverse transcriptase enzyme has reverse transcriptase activity that converts the viral HIV RNA to a single strand copy of HIV DNA as well as having DNA-dependent DNA polymerase activity that copies the single DNA strand into another DNA... Read more »

HIV Replication

Hi Dr. Sherer:Does HIV still replicate or mutates even though a person is undetectable?Thank you....

Response from Renslow Sherer, M.D.

University of Chicago Hospitals

Yes. Even in the presence of a viral load below 50 copies/ml, there is evidence of ongoing replication in sequestered sites of HIV infection such as the central nervous system and the gonads. Different viral evolution patterns have been observed in... Read more »

Replication capacity

What exactly is meant by replication capacity and how can this be tested? Has this become an important part of HIV care??? Can you explain. I have been infected with HIV for 15 years and this is the first I heard of this....

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast

Replication capacity is a measure of how efficiently HIV can grow (or replicate) in experimental conditions. There are a several methods of testing for this viral attribute, but the most common means is through a resistance test called Phenosense... Read more »

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See,I told you HIV replicates a cell's DNA TO RNA

Posted by Anonymous, 1 Reply

The below is plagerized from Gallant ( the guru!)
I know that the present antiretroviral medications do not actually kill the virus.
However, if the medications inhibit the virus from reproducing, doesn't the virus die
by... Read more »

Sbjct: 2nd POST-Virus Replication & OTHER Things

Posted by DUDE

Fellas fellas fellas,,,,
It's certainly time to move one. These HIV tests are very sensative. If you are infected with the HIV virus (or any virus for that matter)
the human body produces anti-bodies. The body reacts. THink of it like this. If you... Read more »

Replicate....

Posted by Anonymous

The HIV virus replicates 9log10 or 10log10(1000 000 000 or 1000 000 0000) each day. So the estimation of virus are 1000 000 000 New virus each day! so why shouldnt your body respond against so much virus? Get a grip virus replication starts nearly... Read more »

DUDE'S NEWS -VIRUS REPLICATION

Posted by DUDE

Subject: SECOND POST-Virus Replication & OTHER Things
Fellas fellas fellas,,,,
It's certainly time to move one. These HIV tests are very sensative. If you are infected with the HIV virus (or any virus for that matter)
the human body produces... Read more »

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