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How Do Hiv Protease Inhibitors Work

Here's a taste of what has to offer on this topic:
Ask the Experts

HIV protease inhibitors

Could you tell me the spectrum of activity and the mechanism of resistance for the antimicrobial HIV protease inhibitors (Ex: Indinavir)and do they work with gram positve/gram negative bacteria. What bacteria does it work against. Or what sites I...
Eric Daar, M.D.

Response from Eric Daar, M.D.

UCLA School of Medicine
...The HIV protease inhibitor selectively blocks the protease enzyme and prevents an infected cell from producing infectious HIV. Resistance develops when Read more »


In taking hydroxyzine pam 25 mg,it states if you are on HIV Protease inhibitors, not to use. What... Read more »
Canadian AIDS Treatment Information Exchange

Emerging HCV Therapies: Possible Interactions With HIV Drugs

...serine-containing enzymes, production of HCV falls. For the treatment of HIV infection, sometimes a class of drugs called HIV protease inhibitors is used as part of combination therapy. These drugs work by targeting enzymes containing the... Read more »
PWA Coalition Colorado

New HIV Protease Inhibitors

...of desperate times with high death rates and lots of complications. In the winter of 1995-96, the introduction of the first HIV protease inhibitors (saquinavir, indinavir and ritonavir) revolutionized the medical care of persons living with HIV... Read more »
U.S. Centers for Disease Control and Prevention

Adding HIV Protease Inhibitors to Rifampin Leads to Adverse Effects

..."Rifampin is the cornerstone of antituberculosis therapy, but induction of hepatic cytochrome P4503A by rifampin markedly lowers HIV protease inhibitor plasma concentrations," noted Dr. David W. Hass of Vanderbilt University School of Medicine... Read more »

An HIV Medication Primer

...entering the cell. But Selzentry has so far been approved only as a second-line treatment, since early trials showed it didn't work as well as other meds in people who had never taken HIV drugs before. More studies are being done to see if it... Read more »
Connect With Others

Thanks for your support and any more advice?

Posted by motherinlaw, 3 Replies His frustration is partly based on the fact that he can not convince her to do anything and short of staying home from work (which they can certainly not afford) he cannot be there to monitor her meds. I don't know where this will lead,... Read more »

hiv & working out/bodybuilding

Posted by windycitypozdude, 2 Replies
...hey everyone! i have always been a "working out," active kind of guy, and always been interested in getting bigger/more muscular, etc. i shy away from the term "bodybuilding" Read more »

Ageing with AIDS

Posted by ScotCharles, 3 Replies
...who have had HIV for more than twenty years and who are now over fifty. I just turned 53. This article is based on years of work that has tracked the incidence of the diseases of ageing in those with HIV. Those studies have found that HIV and... Read more »

What should I think?

Posted by motherinlaw, 9 Replies
I will try not to make this too son called yesterday and told me his wife was not doing well. My HIV negative son and three HIV negative grandchildren may soon lose their HIV positive wife and mother. My son and daughter-in-law seem not to... Read more »