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How Do I Avoid Wasting Syndrome

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Wasting Syndrome

Hormone levels can affect the metabolism. HIV seems to change some hormone levels including testosterone and thyroid. Also, cytokines play a role in wasting. Cytokines are proteins that produce inflammation to help the body fight infections. People with HIV have very high levels of cytokines. This makes the body produce more fats and sugars, but less protein. Unfortunately, these factors can work together to create a "downward spiral." For...
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Proactive approach to avoid facial and body wasting

Doc.Is there any pro-action for avoiding losing body weight or facial wasting?I think that if we can make anything in advance to avoid it it is better to medicated afterwards.Thanks....
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
Hello, and thanks for posting. The best way to prevent fat and facial wasting is to avoid antiretroviral medications that cause this problem. The main culprits are the nucleoside analogues d4T (Zerit), AZT (zidovudine, Retrovir), and ddI (Videx).... Read more »

Avoiding facial wasting.

I am currently taking Trizivir w/ good results(t-cells 1350 viral load undetectable). I've been positive for 10 years and began Trizivir as my 1st drug 2years ago. I do not have facial wasting but am very concerned about it in the future. I...
Graeme Moyle, M.D.

Response from Graeme Moyle, M.D.

Chelsea and Westminster Hospital
Possibly yes. The suitability of a treatment break all depends on how low your CD4 has been in the past.If it has been <200 a break is too risky. Treatment switches are the next question...removing the thymidine analog (AZT). Replacement with... Read more »

article of what drugs to avoid that cause wasting and lean muscle loss

recently.. a few weeks ago I received an e-mail about the side effect of specific drugs that I should avoid that contributed to muscle loss. I thought I printed the article but I can find it. I was from this site. Can you point me in the right...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
I am not sure which article you are referring to. The thymidine analogue nucleoside reverse transcriptase inhibitors (D4T more so than AZT) have been particularly linked to fat loss in the setting of combination anti-HIV therapy. KH... Read more »

What is the best regimen for me to avoid lipoatrophy and facial wasting?

Hi Dr Pierone,I was diagnosed with HIV in mid-2007 only a few weeks after seroconversion and opted for early therapy as part of an ADARC study. My CD4 nadir was in the 500s. After RNA/DNA resistance testing, and a few weeks on Kaletra and Truvada, I...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
Hello and thanks for posting. It is not common to see lipoatrophy with Atripla, but it sometimes does occur. As you say, it is sometimes very difficult to spot early lipoatrophy and distinguish it from natural body changes associated with aging.... Read more »
Connect With Others

Wasting---help me

Posted by Anonymous, 4 Replies
I'm sorry to come on board, but I need help. My husband is wasting away. He's newly on meds, but not gaining. It seems as though his buttcheeks are completely gone. I don't know what to do.

I'm afraid. He's down to 120 and losing despite putting... Read more »

Wasting severly--HELP

Posted by Anonymous, 3 Replies
My loved one is wasting away, how much weight can a person lose and still get healthier? I am very scared and worried about him. Read more »

Wasting

Posted by trnyack, 4 Replies
I was first diagnosed in May of 2001 when My Vl was 750,000 and my cd4 was 42m, since then I have been taking a cocktail of Viracept, Epivir, Zerit, and Bactrim, My weight has dropped from around 160 lbs to just over 120, I am nioticing veins... Read more »