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How Do I Avoid Lipohypertrophy

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Zerit

Common Name: stavudine or d4T Brand Name: Zerit Class: nucleoside analogs (also called nucleoside reverse transcriptase inhibitors, NRTIs or nukes) Standard dose: One 40 mg capsule twice a day for people weighing 132 pounds or more, or one 30 mg capsule twice a day for people weighing less; with or without food, and no food restrictions. Zerit is also available in 15 mg, 20 mg, 30 mg and 40 mg capsules and a powder for oral...
Ask the Experts

What is the best regimen for me to avoid lipoatrophy and facial wasting?

Hi Dr Pierone,I was diagnosed with HIV in mid-2007 only a few weeks after seroconversion and opted for early therapy as part of an ADARC study. My CD4 nadir was in the 500s. After RNA/DNA resistance testing, and a few weeks on Kaletra and Truvada, I...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
Hello and thanks for posting. It is not common to see lipoatrophy with Atripla, but it sometimes does occur. As you say, it is sometimes very difficult to spot early lipoatrophy and distinguish it from natural body changes associated with aging. ... Read more »

Low Dose Naltrexone effectiveness

A Dr. Bihari from NY claims that lipodystrophy and lipoatrophy can be avoided altogether from the nighly use of LDN (low dose naltrexone). http://www.lowdosenaltrexone.org/ldn_and_hiv.htm Are you familiar with that, and what do you think about its...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
Low dose naltrexone for treatment of HIV is a historical footnote from the early era before effective HIV medications became available. I am not aware of any controlled trials of this medication to prevent or treat lipoatrophy or lipohypertrophy. I... Read more »

I switched, but I'm still losing fat!

I have had a lot of problems with lipoatrophy. Now I'm taking atazanavir and saquinavir with a ritonavir booster. I have had an increase in breast size and seem to be experiencing some facial fat loss. I am quite disappointed. I thought I was...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
As a general rule, protease inhibitors tend to be associated with lipohypertrophy. Breast enlargement, abnormal fat deposits, and abdominal protuberance are manifestations of lipohypertrophy. Nucleosides, especially d4T and AZT tend to be... Read more »

How long after treatment would facial wasting start?

how long after starting treatment does facial wasting start? is there any typical time frame and what makes one more susceptible?
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
If facial lipoatrophy occurs, it generally develops in a gradual manner over the course of months to years. There are genetic factors that make some individuals more susceptible to both lipoatrophy and lipohypertrophy. The choice of the... Read more »
Articles
The Well Project

Lipodystrophy, Body Changes and HIV/AIDS

Table of Contents What Is Lipodystrophy? Body Shape Changes Metabolic Complications What Causes Lipodystrophy? Can Lipodystrophy Be Treated? Caring for Yourself What Is Lipodystrophy? Lipodystrophy means abnormal fat... Read more »
The Well Project

HIV/AIDS and Lipodystrophy Treatments Part II: Treatments for Fat Loss

Table of Contents Fat in the Body Switching HIV Drugs Fat Loss in the Face Temporary Facial Fillers Permanent Facial Fillers Taking Care of Yourself Fat in the Body Fat is needed for the body to function. It plays an... Read more »
Project Inform

Tesamorelin and Excess Deep Belly Fat

Introduction Body Shape Changes Study Volunteers Study Design Side Effects Study Results Project Inform's Perspective Introduction Studied as a way to reduce excess deep belly fat, the synthetic human growth hormone... Read more »
The Well Project

HIV/AIDS and Lipodystrophy Treatments Part III: Treatments for Metabolic Changes

Table of Contents Fat in the Body Metabolic Problems Treatments Taking Care of Yourself Fat in the Body Fat is needed for the body to function. It plays an important role inkeeping the skin and hair healthy, protecting... Read more »
Connect With Others

Excessive Mastubation

Posted by Anonymous, 5 Replies
Ever since I found out that I'm poz, I've been spending a lot more time mastubating. Is that normal? Or could it be because of the amount of time I've been spending reading posts about sexual issues? Pleasing myself has become an every day thing... Read more »

Hiding behind HIV

Posted by Magnet, 4 Replies
I write this question in the hope of gaining insight from both HIV positive gay men as well negative men in "magnetic partnerships". I only now discovered this term "magnetic", as it relates to my life! It can no longer be a twist of fate that my... Read more »

can you avoid lipodystrophy?

Posted by hopefulone, 4 Replies
s there a way you can avoid or lesson the impact of lipodystrophy if on atripla? good diet and regular exercise? or regardless of exercise and diet youre going to change? Read more »

Egrifta tesamorelin, is it available?

Posted by artnut, 2 Replies
Positively Aware has an article (July/August 2010)on the FDA approving Egrifta for the treatment of belly fat. Is it available? Has anyone had any experience with it? The biggest problem seems injecting oneself. How about blood sugar levels? ... Read more »