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How Common Is Lipodystrophy

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AIDS InfoNet

Body Shape Changes (Lipodystrophy)

No researcher has suggested that people with lipo should stop taking ART. What Causes Lipo? We do not know what causes lipo. There are different causes for fat loss and fat gain. Fat Loss Zidovudine (Retrovir, AZT) and stavudine (Zerit, d4T) are linked to fat loss. Efavirenz (Sustiva) may also contribute. Fat Gain One theory is that protease inhibitors interfere with the body's processing of fat. However, some patients who have never...
Ask the Experts

Just How Common Is Facial Fat Loss?

I was diagnosed 2 months ago. Apart from all the other issues I'm trying to deal with right now, I am really worried about lipodystrophy. I am a medical student and have been doing modeling here and there. I understand that fat redistribution...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
The risk of lipoatrophy on Atripla would be in the 10 percent range after 3 years of exposure. This estimate is an extrapolation from the ACTG 5142 trial where body fat measures were tracked in response to different starting regimens. The risk would... Read more »

Is it lipodystrophy or not

Hi, My stats are: positive for 10 years, never had an OI or AIDS diagnosis. On and off meds, currently off for 1 1/2 yrs. CD4 in the 500s and Viral Load around 380. It has never been over 1000. I am also 51, female and post menopausal. I have what...
Brian Conway, M.D.

Response from Brian Conway, M.D.

University of British Columbia
First, I am very pleased that your numbers are what they sounds as if you do not need treatment at this time...The area you describe in the front of the neck is not a common spot for lipodystrophy, especially without any other changes... Read more »

Lipodystrophy and Hypertention

Keith, why do you write about hypertention not being related to HAART when articles like this are published?Hypertension Is Common Among HIV-Infected Patients with LipodystrophyWESTPORT, CT (Reuters Health) - High blood pressure is a common finding...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
The link between lipodystrophy and hypertension is far from established despite some intriguing pilot studies such at the article by Fred Sattler that you quoted. Larger trials have failed to link HIV treatment with hypertension (indinavir most... Read more »

about anabolic steroids for lipodystrophy

in an earlier question you stated that anabolic steroids have been useful for lipodystrophy. My dr. said that steroids have no effect in preventing lipo. Could you elaborate on their benefits...
Marc Hellerstein, M.D., Ph.D.

Response from Marc Hellerstein, M.D., Ph.D.

University of California Berkeley & San Francisco
I'm not sure what was said before about anabolics and lipodystrophy. Here's what I'd say.Lipodystrophy refers to loss of fat from the extremities. There is no known treatment of any type that is effective against this complication.... Read more »
Connect With Others

exercise and PI lipodystrophy

Posted by Anonymous, 3 Replies
i have been on zerit, epivir and crix for more than one year.
i have lipodystrophy (no more buttocks, fat loss in face and a paunch). I have always been an avid exerciser -- my doc has told me to STOP exercising, that it worsens the situation.
i... Read more »


Posted by Anonymous, 1 Reply
anyone who will talk about this?

Read more »

Lipodystrophy and relationships

Posted by capri75
Anyone out there who has experienced a feeling of neglect in a relationship because they have lipodystrophy even thought they have healthy blood counts and full of energy. Anyone who knows a dating sites for people with lipodystrophy? Read more »

Lipodystrophy and/or Neuropathy?

Posted by Anonymous, 2 Replies
Is it possible to experience lipodystrophy and neuropathy within 2-3 months of HIV exposure, or are these conditions generally symptomatic of long-term HIV status? I have noticed significant swelling under my arm/ beside my right breast. I'm not... Read more »