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Hiv Virus Affect B Cells

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The Well Project

Understanding CD4 Cells and CD4 Cell Tests

The Basics CD4 Count and HIV CD4 Count and HIV Treatment CD4 Cell Test The Bottom Line The Basics Your immune system protects your body by fighting germs and infections.White blood cells are an important part of your immune system. HIV infects and destroys a type of white blood cell called aCD4 cell (sometimes called a T-cell). As the immune system loses CD4 cells, it becomes weaker and is less able tofight off germs. When it...
Ask the Experts

how do depleted numbers of CD4 cells affect antibody production

and cell mediated immunity?what affect do antibodies have on the numbers of HIV particles?thanks...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
CD4 cells make lots of chemicals and hormones that are required for normal function of b cells and cytotoxic t cells (CD8 cells). Thus, if their number is decreased significantly, these other cells are not signalled appropriately to perform their... Read more »

Blood for T cell test taken during glucose tolerance test: could it affect the results of the T cell test?

Dr.Moyle,During a glucose tolerance test (I was actually having it done per your recommendation), they drew blood for a T cell subset. I was to have had a T cell subset done late next week, but I thought that, since they had the needle in my vein...
Graeme Moyle, M.D.

Response from Graeme Moyle, M.D.

Chelsea and Westminster Hospital
it should make no difference. There are many things reported to modestly influence CD4 and VL tests but fed and fasted states are not one that is considered important. Vigourous excercise, smoking, infections and vaccinations are the most well known... Read more »

Heat resistance of HIV virus cells vs. RBCs

Has there been any research performed regarding the ability to destroy HIV cells using heat (while not impacting RBCs)? Do you think this is possible given the DNA/RNA structure of HIV virus cells versus the protein and lipid bilayer of the RBC? I...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
I am not a protein chemist. Heat will destroy the virus, and will also destroy RBCs. I don't know what the differential temperature, if any, might be. I am not aware of any research looking at this specific question.MH... Read more »

Can HIV virus be transfered by ejaculate without sperm cells?

Dear Dr.BobMaybe strange question:Is there lower transmision risk if there are no sperm cells in ejaculat? (in case of infertility). I suppose there is free RNA ( similar as in blood plasma ).Thank you very much for you answer. ...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hi,Ejaculate contains many kinds of cells besides sperm, and yes, some of them can harbor HIV. Consequently, no, you cannot count on infertility decreasing HIV transmission risk.You are very welcome!Dr. Bob... Read more »
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Can Herpes Virus affect testing?

Posted by Anonymous, 1 Reply
I had unprotected sex with a girl of unknown status, 1 week later I got blisters and was diagnosed with Herpes, as if that wasn't bad enough I began having other symptoms. I was tested by elisa at 10 weeks and negative. Can the herpes infection... Read more »

Do anybody know about CD4 cells count?

Posted by Anonymous, 1 Reply
Hi guys,

I have a question about my tests - in fear of HIV infection because of a bad incident and symptoms not long after, I went to have my blood tested for HIV as well as other infections - the PCR and antibody test both turned out Negative, but... Read more »