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Hiv Structure And Function

Here's a taste of what has to offer on this topic:
Get the Facts
AIDS InfoNet

Other Antiretroviral Drugs in Development

...The inner core of HIV is called the nucleocapsid. It is held together by structures called "zinc fingers." Zinc finger inhibitors (or zinc ejectors) are drugs that can break apart these structures and prevent the virus from functioning. Scientists believe that the nucleocapsid core cannot mutate very easily, so a drug that works against zinc fingers might be effective for a long time. Unfortunately, zinc fingers are not only used by the HIV...
Ask the Experts

normal tests

Hi Dr,Could you please tell me why basic blood tests ie: FBC appear normal even with advanced HIV? Thank you
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
...Because, although HIV affects many organs and tissues, many retain there structure and function through infection. Read more »

Can HIV damage the brain

I am HIV+ with CD4 count 555 and V.L undetectable for the last six month. A year ago I was very ill and my right leg and my right hand was paralize (useless). Once I got treatement with HIV my leg is ok, But I have a problem with my right hand (i...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...If the brain has been structurally damage due to HIV or an AIDS-related infection (like toxoplasmosis or dJC virus infection) then the recovery is often similar Read more »


I am nurse who visits patients at home. I have a patient diagnosed with AIDS/PML who is doing very well physically but who has significant memory deficits.Where can I find information on PML in general and on behavioral treatments (if any)? All...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...situation. Even with improvement on HIV meds can stabilize the situation but there is no proven therapy to heal/repair the structural damage. I have had patients who improve their activity level with physical therapy but actually improving... Read more »

reverse transriptase enzyme

Besides retrovirus's does any other body process's require this enzyme i.e is the enzyme required by healthy cells in the body, like skin cells,liver repair etc? what is the difference between rna and dna?
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
...function of the protein in healthy individuals.RNA and DNA are both forms of genetic material. They differ somewhat in their structural details and specific functions. DNA is the storage genetic material for human genes, whereas RNA is used as... Read more »
Henry J. Kaiser Family Foundation

Meth Use, HIV Infection Linked to Changes in Brain Structure That Can Impair Cognitive Functions, Study Says

... Methamphetamine use and HIV infection might significantly alter the size of a person's brain structure, leading to cognitive function impairments such as difficulties learning or processing information, according to a study published Read more »
U.S. Centers for Disease Control and Prevention

Rhode Island: HIV, Alcohol Topic for Brown Study

...Center on HIV. Center researchers will conduct a three-year study examining changes in brain structure, metabolism, and cognitive functioning of HIV-positive persons who are light or heavy drinkers. Another project will target HIV-positive heavy... Read more »
Terri Wilder

The Death of an HIV/AIDS Organization

...20 years. It's a disgrace to see it disappear when it is still so needed by people living with HIV/AIDS. This agency had a structure that insured a passionate and committed response to the diverse and changing needs of people living with... Read more »
U.S. National Institute of Allergy and Infectious Diseases

Promising HIV Vaccine Strategy Identified in Monkey Studies

...targets will be stimulated." Current products in human vaccine trials primarily induce immune responses to envelope or other structural proteins of HIV rather than to functional proteins like Tat, which is required for the virus to replicate. ... Read more »
Connect With Others

50% of HIV+ Develop Neurocognitive Impairment

Posted by ScotCharles, 3 Replies
...are under "neurocognitive." In addition, a subset of these patients received brain-imaging studies, including studies of the structure of their brains and whether there might be the presence of abnormal signals in the brain. It was found that... Read more »

Director of Treatment & Prevention Advocacy

Posted by Robert1
...experience in HIV/AIDS care and treatment desirable but not required Knowledge of basic research, drug development and approval structures and organizations Ability to work well with others and build a team Excellent project planning and... Read more »

Scientists Discover 'Natural Barrier' to HIV

Posted by MOCHA
...Langerin is produced by Langerhans cells, which form a web-like network in skin and mucosa. This network is one of the first structures HIV confronts as it attempts to infect its host. However, "we observed that Langerin is able to scavenge... Read more »


Posted by Anonymous, 2 Replies
Would PN at 11 weeks after infection be fairly inconsistant? What I am experiencing started a few days ago and began with tingling feet and arms (not hands). All limbs had pins and needles later that night, at the same time. Since then I have had... Read more »