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Hiv Reverse Transcription

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AIDS InfoNet

Drug Names and Manufacturers

Reverse Transcriptase Inhibitors ("Nukes") Non-Nucleoside Reverse Transcriptase Inhibitors Protease Inhibitors Integrase Inhibitors Attachment and Fusion Inhibitors Antisense Drugs Immune Modulators None of these drugs can kill the HIV virus, but each class slows down the multiplication of the virus (replication) in a particular way. Combination medications: Some manufacturers have combined more than one drug into a single...
Ask the Experts

Reverse transcriptase inhibitors effect on telomeres

I recently started on Atripla and was trying to understand how it works and potential long term effects. So as I understand it (and I'm not a microbiologist by any stretch) the main purpose of the Sustiva in Atripla is to inhibit the reverse...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
I am not aware of any data that has shown that nucleoside reverse transcriptase inhibitors (that are HIV DNA chain terminators not directly involving human DNA) clinically impact human chromosome or telomore length/function. Non-nucleoside RT... Read more »

Reversal of HIV in 3 month old infants?

I am currently working with a set of 11 year old twins who tested postitive for HIV at birth. Their records indicate that they were given AZT every 3 hours at birth, and tested negative at 3 months old. The result stated a "reversal" of...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
You don't indicate what tests were performed. HIV antibody tests in infants born to HIV positive mothers can be positive for 12-18 months following birth (becaue of placental pasage of maternal HIV antibodies), and the child will not be... Read more »

does aspen lamzid reverse the hiv infection

H my name is lawrence from south africa,i met this girl last year november 2009 i slept with her for the first i used protection,but for the second time i didn't use the protection and we slept more 5times,i asked her to go for an HIV test on...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Hello Lawerence and thanks for your post from South Africa.What you ask about is called post-exposure prophylaxis, or PEP (there's a whole category on this topic on this forum). Lamzid, or AZT+3TC (known here in the US and other parts of the... Read more »

can aids be reversed to just hiv possitive?

i was diagnosed recently with a cd4 of 41 viral load over a milion, been on meds a month. after 1st month cd4 up to 300 vial down to 1200. if meds continue to work will i be out of aids and back to an hiv catagory?> i am very...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hi,This question of HIV positive versus "full blown AIDS" comes up fairly frequently. We don't use the term "full blown AIDS" anymore, as there is no such thing as partially blown AIDS. In many ways we really shouldn't... Read more »
Connect With Others

reversing lipodystrophy....

Posted by Anonymous, 1 Reply
Positive since 2003 full blown aids. Was on Kaletra and combivir. Reached non-detectable, and cd4 rising as expected. Into 3rd year noticing increase in truncal girth. Waist went from 27in. to 32in of hard solid protruding fat. Arms, legs, face... Read more »

HIV-1? HIV-2? HIV-O?

Posted by Anonymous, 6 Replies
We didn't even know about HIV until the 1980's. So, we invented a HIV1 test, only to find there is a HIV2. So, we invented a HIV2 only to find out there is a HIV-O. Why are we so ignorant to think there couldn't be another strain...for which we... Read more »


Posted by Anonymous
Validation: Search for the Gold Standard

HIV tests should be validated against direct isolation of the virus from people that test positive, and lack of isolation in people who test negative.
Instead of just comparing people with AIDS against healthy... Read more »

New here - HIV- female with HIV+ male partner

Posted by iSerenity, 2 Replies
Hi, I'm new here myself, glad I found this site. I'm HIV- and involved with a wonderful man that is HIV+. Already have two kids from a previous relationship. We've been together for most part of two years now in a long distance relationship... Read more »