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Hiv Reservoir

Here's a taste of what has to offer on this topic:

Danish Study Targets HIV Reservoir, in Latest Search for HIV Cure

Danish researchers have begun testing panobinostat, an HDAC inhibitor, in 15 patients, in an attempt to find an HIV cure. HDAC inhibitors, which are traditionally used to treat cancer, are now being studied for their potential to flush HIV out of... Read more »

Very Early HIV Treatment May Limit "Seeding" of Latent HIV Reservoirs, Study Finds

Early HIV treatment, specifically during acute HIV infection, can limit the virus from forming HIV reservoirs in central memory CD4+ cells, according to study results presented at CROI 2013 in Atlanta, Ga. Researchers in Thailand screened 52,767... Read more »

News & Views: HIV Reservoir Discovered in the Lungs; The Last HIV Conference of the Year; Helping Puerto Rican IDUs; and More

HIV News & Views, October 9, 2014 - October 9, 2014 Top Stories at Read Past Newsletters Change/Update Subscription Dear Readers, This week, I'm back from San Diego... Read more »
Ask the Experts

your opinion about reservoir hiv

Hi,Just read an article here on scientists finding that hiv still infects cells by attraction rather than in a hidden reservoir. I wish I could find it again and I might sound more intelligent. I got the idea that it just shut the door on a...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hi.Relax Max! These discoveries actually bring us closer to a cure (either functional or total eradication)! As the author states: "Determining the location of viral reservoirs in the body, as well as mechanisms that maintain it, are important... Read more »

Radiations to destroy HIV in reservoirs?

If radiations would target directly the cells where HIV latently hides is there a possibilty the virus could be destroyed like cancers? A study suggested that with the help of nanotecnology antibodies could be carried with radioactivity in order to...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
Yes radiation could kill HIV infected cells. The strategy you cite might be possible if it could be designed to not kill other bystander uninfected cells or result in any long term complications associated with radiation.... Read more »

Eliminating HIV reservoirs might damage cells?

Dear Dr. Wohl:Once you said in this forum that the researcher (I cant remember his name) who did the study on valproic acid is working at your university.Imagine his theory worked and he could figure something to force the virus to leave the cells...
David Wohl, M.D.

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill
Dear John,I agree with your affection for your gray cells. As Woody Allen said, "My brain?! That is my second favorite organ."David Margolis is trying to use valproic acid to inhibit cellular processes that keep HIV latent (or inactive)... Read more »

viral reservoirs

Can you please explain how HIV exists in reservoirs in the body? My partner has undetectable viral load, yet his doctor, for whom I have great respect, explained to me about viral reservoirs when I asked why he continues to be ill (fungal infections...
Eric Daar, M.D.

Response from Eric Daar, M.D.

UCLA School of Medicine
Hi Laurie,When people discuss HIV reservoirs in the body they are generally speaking of places where virus may persist while having undetectable viral load on antiretroviral... Read more »