Hiv Reservoir

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Call for a Task Force on HIV Reservoirs

Posted by new2this2010

Global Commitment Urgently Needed Towards an HIV Cure: Call for a Task Force on
HIV Reservoirs
http://www.emailwire.com/release/55776-Global-Commitment-Urgently-Needed-Towards-an-HIV-Cure-Call-for-a-Task-Force-on-HIV-Reservoirs-.html

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Fighting HIV with cancer drugs

Posted by new2this2010, 3 Replies

Looks very very promising:

http://www.walb.com/global/story.asp?s=13054103 Read more »

HIV May Damage Brain Tissue

Posted by ScotCharles, 1 Reply

Los Angeles Times Examines Research Surrounding Long-Term Effects of HIV on Brain Tissue

November 8, 2005

The Los Angeles Times on Monday examined research into the long-term effects of HIV on brain tissue (Brink, Los Angeles Times, 11/7). A study... Read more »

HIV-PET Scan

Posted by Anonymous

PET Scanning Helps Define Course of HIV-1 Infection: A Newsmaker Interview With C. David Pauza, PhD
Laurie Barclay, MD
Sept. 18, 2003 Editor's Note: It may be possible to use positron emission tomography (PET) scans to diagnose HIV reservoirs and... Read more »

Acute HIV Infection Overview

Posted by Anonymous

1. Acute HIV-1 Infection
Marcus Altfeld and Bruce D. Walker

Introduction

Acute HIV-1 infection presents in 40 - 90 % of cases as a transient symptomatic illness, associated with high levels of HIV-1 replication and an expansive virus-specific immune... Read more »

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Ask the Experts

your opinion about reservoir hiv

Hi,Just read an article here on scientists finding that hiv still infects cells by attraction rather than in a hidden reservoir. I wish I could find it again and I might sound more intelligent. I got the idea that it just shut the door on a...

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation

Hi.Relax Max! These discoveries actually bring us closer to a cure (either functional or total eradication)! As the author states: "Determining the location of viral reservoirs in the body, as well as mechanisms that maintain it, are important... Read more »

Radiations to destroy HIV in reservoirs?

If radiations would target directly the cells where HIV latently hides is there a possibilty the virus could be destroyed like cancers? A study suggested that with the help of nanotecnology antibodies could be carried with radioactivity in order to...

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine

Yes radiation could kill HIV infected cells. The strategy you cite might be possible if it could be designed to not kill other bystander uninfected cells or result in any long term complications associated with radiation.... Read more »

Eliminating HIV reservoirs might damage cells?

Dear Dr. Wohl:Once you said in this forum that the researcher (I cant remember his name) who did the study on valproic acid is working at your university.Imagine his theory worked and he could figure something to force the virus to leave the cells...

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill

Dear John,I agree with your affection for your gray cells. As Woody Allen said, "My brain?! That is my second favorite organ."David Margolis is trying to use valproic acid to inhibit cellular processes that keep HIV latent (or inactive)... Read more »

Latent Reservoirs -Where, When, and How Long?

My question relates to latent HIV reservoirs. I would like to know to the best of your knowledge the different types of cells and tissues that might act as reservoirs for...

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill

We are learning a lot about so called latent reservoirs - cells that the virus enters but which replicate slowly keeping these viruses out of the reach of HIV medications. These cells are found throughout our body as part of our immune system.... Read more »

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Articles

A Common Blood Product Called IVIG May Help Clear the HIV Reservoir

During an oral presentation at CROI 2009 in Montreal, Canada, Dr. Magnus Gisslen detailed early findings from a small proof-of-concept study using high-dose intravenous (in the vein) immunoglobulin (IVIG) to reduce the amount of HIV found in cells... Read more »

Researchers Discover "Reservoir" That Allows HIV to Remain Infectious Despite Treatment

Researchers at Brigham Young University and the Johns Hopkins School of Medicine have discovered a human cell "reservoir," called follicular dendritic cells, that allows HIV to stay in an infectious state and not respond to antiretroviral drugs,... Read more »

High-Dose Intravenous Immunoglobulin May Reduce Latent HIV Reservoir in Resting CD4+ Cells, Study Suggests

There's nothing like hearing the results of studies directly from those who actually conducted the research. In this interview, you'll meet one of these impressive HIV researchers and read his explanation of a study he presented at CROI 2009. After... Read more »

NIAID Workshop: Elimination of HIV Reservoirs

On Friday, January 15, the National Institutes of Allergy & Infectious Diseases (NIAID) sponsored a scientific workshop entitled "The Next Challenge: Elimination of HIV Reservoirs." The event took place during the Keystone conference on HIV... Read more »

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