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Hiv Replication And Viral Load

Here's a taste of what has to offer on this topic:
Henry J. Kaiser Family Foundation

HIV Can Replicate in Intestinal Lining Even After HAART Reduces Viral Load, Study Says

HIV can replicate and suppress the immune system in the intestinal lining, even after blood tests show that highly active antiretroviral therapy is reducing viral loads, according to a study published in the August issue of the Journal of Virology ... Read more »
Treatment Action Group

HIV Replication and Persistence in T Follicular Helper Cells

Following up on the recent post on T follicular helper cells(TFH) , a study published on December 17th in the Journal of Experimental Medicine reports that TFH represent a major site of HIV replication andpersistence. The finding is not... Read more »
Treatment Action Group

Posttreatment Control of HIV Replication and Prospects for a Functional Cure

In a review article in the open-access journal Retrovirology , Guido Vanham and EllenVan Gulck provide a detailed accounting of the multitude of immune-basedtherapy (IBT) studies that have been conducted over the years (in both peoplewith HIV and... Read more »
Ask the Experts

Stopping viral load replication

When first diagnosed 3 years ago my viral load was in the hundred thousands, I believe it was 7 hundred thousand. According to this particular strain, I had been infected for 13 years before detection. Immediately started on sustiva and...
Renslow Sherer, M.D.

Response from Renslow Sherer, M.D.

University of Chicago Hospitals
This is a very good question.The best antiretroviral therapy lowers the plasma viral load - which is really a test of the amount of HIV RNA in the blood - by 3-5 logs, i.e. it reduced your viral load from 750,000 to 75,000 (one log) to 7,500 (two... Read more »

Viral Replication

I am confused about viral replication. The current antiretiroviral drugs prevent replication. However, when the meds are stopped is the virus still present in the infected cell and able to start replicating again?...
Renslow Sherer, M.D.

Response from Renslow Sherer, M.D.

University of Chicago Hospitals
Yes to both questions. The current antiretroviral drugs are 'static' drugs, i.e. they don't kill the virus, but they do prevent replication. Fortunately, the consequences of stopping replication are prolonged length of life and a... Read more »

viral replication assay

Can you tell me if and when you use the viral replication assay and how important has this test become? Is it essential to figure out the next regimen for someone who has been on multiple regimens?...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
I believe you mean replication capacity (RC) assay, which has up to this point been included with a phenotypic resistance test from one of the companies that provides such tests. Preliminary studies suggest that a low RC might predict slower... Read more »

Follow-Up on Low Level Viral Replication Issue

Dear Dr. Holodniy:Thanks for your earlier response about my low level viral replication. I took your advice and did nothing, rather than adding another drug to my Atripla regimen, such as Isentress (which would have added toxicity and possibly...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
Thanks for the follow-up. yes, I would consider it a blip, given the very low levels of viral load. In many people the viral load level is not zero in the blood. Undetectable means below the threshold of the assay and not zero. There is more... Read more »
Connect With Others

hiv viral load

Posted by Anonymous, 1 Reply
and Perhaps a Lifesaver?

By Paul Galatowitsch, Antonio Urbina and Timothy Law Snyder

Paul Galatowitsch is a health care consultant. Antonio Urbina is the director of clinical HIV and AIDS education at St. Vincent's Hospital. Timothy Law Snyder is a... Read more »

See,I told you HIV replicates a cell's DNA TO RNA

Posted by Anonymous, 1 Reply
The below is plagerized from Gallant ( the guru!)
I know that the present antiretroviral medications do not actually kill the virus.
However, if the medications inhibit the virus from reproducing, doesn't the virus die
by... Read more »

CD4 668 - Viral Load 227567 ? about viral load

Posted by Courtkidx, 1 Reply
I just got these results via phone and im just curious if anyone can tell me if I should be worried about my semi high viral load? I know my cd4 count is good. I am newly diagnosed as of dec. 30, 2009. Any info would be appreciated. Read more »

Help me make sense of these results if you can - low viral load

Posted by Souledout, 5 Replies
Hi, I tested positive on 18th september. Massive shock all round and then the usual route of worry, stress and then acceptance. Great support from my friends and partner which has helped a great deal.

My doctor thinks my infection was in the last 3... Read more »