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Hiv Receptor

Here's a taste of what has to offer on this topic:
U.S. National Institute of Allergy and Infectious Diseases

NIAID Scientists Identify New Cellular Receptor for HIV

A cellular protein that helps guide immune cells to the gut has been newly identified as a target of HIV when the virus begins its assault on the body's immune system, according to researchers from the National Institute of Allergy and Infectious... Read more »
Treatment Action Group

Co-Receptor Conundrum

Since the late 1980s researchers have recognized that HIV isolates (viruses sampled from infected individuals) can be divided into one of two categories based on their ability to replicate in particular cells in the laboratory. Originally, a... Read more »
U.S. Centers for Disease Control and Prevention

Safety Concerns Cast Shadow Over Novel Class of HIV Drugs

A new class of experimental HIV drugs, CCR5 receptor antagonists, is raising safety concerns. Designed to block a secondary but crucial doorway through which HIV enters cells in the body, the drugs would represent a shift in the fight against HIV,... Read more »
Ask the Experts

HIV or Meds causing abnormal CD4 receptors?

Dr. Boyle, Do all HIV positive folk have abnormal CD4 cell receptors? If so, is this caused by HIV infection or is it a side effect of meds? How do these abnormalities manifest they cause symptoms or compromise immune...
Brian Boyle, M.D., J.D.

Response from Brian Boyle, M.D., J.D.

Cornell University, Weill Medical College
Your question is a little confusing, but I'll try to give you the answer your looking for. CD4+ T cell deficits are not present in all patients with HIV, and the time to develop signficanty immunocompromise (low CD4+ T cells) may vary widely... Read more »


What are co-receptors? What is their significance in HIV infection?...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
Coreceptors are molecules on the surface of a cell, in addition to CD4, that HIV requires to lock onto a cell in order to gain entry and infect the cell.... Read more »


i have recently read that hiv requires co-receptors to bind and be engulfed in the bloodstream. is there any evidence that these coreceptors may be absent from certain parts of the body - for example, parts of the skin compared to mucous membranes?...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
Alternatively, another reason for infection via mucosal membranes is the large number of dendritic cells which process HIV and take it to the lymphnodes were rapid infection insues.... Read more »

t4 receptors

Since t4 cells have receptors that hiv binds what does hiv have that causes this binding? Can any part of hiv surface bind to a t4 receptor? Is this binding process purely a chemical reaction? I have noticed over the last ten years when my lipids...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
Great questions. HIV has a very specific genetic sequence (and therefore structure) of its envelop protein that binds to the CD4 receptor in a tight lock-and-key way. The relationship between your lipids and HIV viral load is not directly related to... Read more »
Connect With Others


Posted by mobieorly123, 1 Reply
For a long time on an off I've had lymphnode issues when I get sick, trouble getting rid of colds and other such thing...

HIV'ers call people like myself worry wells and hypocondriacs.

Let me introduce HTLV1 and HTLV2
Human t cell lymphoma 1-2 and its... Read more »

alguna persona de puerto rico?

Posted by Anonymous, 1 Reply
con tratamiento Read more »

Have I Gone from HIV to AIDS? HELP!!!!

Posted by CLT, 4 Replies
I will keep my story pretty short. March 20th 2006 I found out I was positive. My CD4 was 336 and my viral load was 55,000.

August 14th I take some more labs and had not been able to go back to the doctor until today October 30th. I found out my CD4... Read more »

How long have I had HIV?

Posted by redbull, 1 Reply
Do your #'s necessarily dictate how long you have had HIV? When I was diagnosed in 5/09 my cd4 was 94 and my VL was 400K. After being on atripla for 2 1/2 months my cd4 has jumped from 94-210 and my VL has dropped to only 500! My dr told me... Read more »