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Hiv Protease Structure

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Ask the Experts

Protease Structure

A news report today said that a new computer program has enabled gamers to help figure out the structure of protease and that this breakthrough will lead to new drugs being developed. There are already lots of protease inhibitors on the market so I...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Hi and thanks for posting.The HIV protease inhibitors were designed with the knowledge of the atomic structure of the HIV protease. What's new is the idea of using gaming technology to get communities of people involved in design of... Read more »

dietary protease vs HIV protease

My mother who is a dietician feels my regimen of Kaletra, Invirase and Truvada is interfering with... Read more »
Articles
Canadian AIDS Treatment Information Exchange

Is Protease Inhibitor Monotherapy Sufficient to Keep HIV Under Control in the Brain?

Shortly after HIV enters the body it infects cells of the immune system. As these infected cells are carried by the blood stream, HIV is spread throughout the body, including to the brain and spinal cord -- the Central Nervous System (CNS). HIV does... Read more »
San Francisco AIDS Foundation

Tipranavir: The First Nonpeptidic Protease Inhibitor

Introduction Recent Data BI 1182.2 BI 1182.52 Resistance Profile Drug Interactions RESIST Selected Sources Introduction Resistance to anti-HIV medications is an ongoing dilemma. A recent study in 16 European countries and Israel found... Read more »
San Francisco General Hospital

How the Protease Inhibitors Work

The protease inhibitors represent one of the best examples of the application of basic scientific knowledge to rational drug design. Relatively soon after the discovery of HIV, researchers were able to elucidate the genetic structure of the virus... Read more »
AIDS Community Research Initiative of America

Seeing Double: A Tale of Dual Protease Inhibitors

It's hard to believe, but it has been more than five years since the protease inhibitors (PIs) made their therapeutic debut and forever changed our approach to managing HIV. Perhaps the most impressive aspect of this milestone is that researchers... Read more »
Connect With Others

lipodystrophy from protease inhibitors

Posted by Anonymous, 4 Replies
I have known about my HIV+ status now for 6 years, and God has blessed me with continued good health. I have accessed all the major medications, plus vitamins to help fight the disease. Once I started taking the new protease inhibitors, I started... Read more »

Abbott pharmaceuticals price gouging protease inh

Posted by BabyPeanut
Editorial, The Center for AIDS (12/15/03)

In a move that startled healthcare professionals and community members alike, Abbott pharmaceuticals announced a price increase of almost 500% for its protease inhibitor ritonavir (Norvir). Norvir is widely... Read more »

Protease Inhibitors - Hemophilia bleeds

Posted by akcol
Hi, my fiance is a Long Term NonProgressor - 24 years positive, co-infection HCV, with severe Hemophilia A.

This is a question for the gentlemen with Hemophilia please.
We're requesting any input about any Hemophilic PI increased unusual bleed... Read more »

10 years and protease are finally working...

Posted by Anonymous
10 years and protease are finally working for me. It only took
going through all four. Mode of transmission: unknown.
Ex-hustler, dope fiend, alcoholic, sadomasochist,recovering
southern baptist, living in Los Angeles but use to travel
extensively,... Read more »

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