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Hiv Protease Inhibitor Mechanism Of Resistance

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HIV protease inhibitors

Could you tell me the spectrum of activity and the mechanism of resistance for the antimicrobial HIV protease inhibitors (Ex: Indinavir)and do they work with gram positve/gram negative bacteria. What bacteria does it work against. Or what sites I...
Eric Daar, M.D.

Response from Eric Daar, M.D.

UCLA School of Medicine
...The HIV protease inhibitor selectively blocks the protease enzyme and prevents an infected cell from producing infectious HIV. Resistance develops when Read more »

what is HIV PROTEASE INHIBITORS.

In taking hydroxyzine pam 25 mg,it states if you are on HIV Protease inhibitors, not to use. What... Read more »

Pharmacokinetics

Dear Dr. Holodniy,Thanks for answering my previuos question. Specifically, I'm looking for effects... Read more »
Articles
U.S. Centers for Disease Control and Prevention

Adding HIV Protease Inhibitors to Rifampin Leads to Adverse Effects

..."Rifampin is the cornerstone of antituberculosis therapy, but induction of hepatic cytochrome P4503A by rifampin markedly lowers HIV protease inhibitor plasma concentrations," noted Dr. David W. Hass of Vanderbilt University School of Medicine... Read more »
AIDS Treatment News

Liver Fibrosis in HIV/Hepatitis C Coinfection: HIV Protease Inhibitors May Be Protective

...A study of 182 patients at a major hospital in France suggests that HIV protease inhibitors may help to reduce liver fibrosis and cirrhosis in patients with both HIV and hepatitis C. ( 1 ) This study, conducted in patients Read more »
U.S. Centers for Disease Control and Prevention

Researchers Uncover Insulin Resistance Link

...cause diabetes," said Paul Hruz, a WU professor of pediatrics and biology who led the team. The full study, " Effects of the HIV Protease Inhibitor Ritonavir on GLUT4 Knock-Out Mice ," was published in the Journal of Biological Chemistry ... Read more »
PWA Coalition Colorado

New HIV Protease Inhibitors

...of desperate times with high death rates and lots of complications. In the winter of 1995-96, the introduction of the first HIV protease inhibitors (saquinavir, indinavir and ritonavir) revolutionized the medical care of persons living with HIV... Read more »
Connect With Others

Ageing with AIDS

Posted by ScotCharles, 3 Replies
...likely that a person with HIV will get age related cancers, Alzheimer's, kidney disease, liver disease, and heart disease. The mechanisms are complex, but HIV and PIs disrupt, each in their individual ways, the chemical functioning of the... Read more »

Am I Infected

Posted by delhiguy, 3 Replies
I am 30 YO guy. Worried that I may have got infected. I met this friend of mine on 5th of Dec 2010 which was just a causual meeting after 5 years. After having drinks she started touching me and I got aroused and we end up mating. While in act, she... Read more »

Im new and want friends!=)

Posted by chula93, 1 Reply
hey! i am new here. I have had HIV all my life. i was born with it. Anyway, i thought it would be nice to talk to other people. Dame un mesaje si tu quieres=) Read more »

Lost

Posted by LostNconfused, 5 Replies
I tested positive 3 days before Christmas and I think I am still numb to the fact. I haven't told any friends or family because I really don't know how and most are judgemental and I'm sure will walk away. But I guess if they do, then I didn't need... Read more »