Hiv Membrane Fusion

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Fusion and Attachment Inhibitors

Note: Several fact sheets describe drugs that are being tested against HIV: Fact Sheet 410 : nucleoside analog reverse transcriptase inhibitors (nukes) Fact Sheet 430 : non-nucleoside analog reverse transcriptase inhibitors (NNRTIs or non-nukes) Fact Sheet 440 : protease inhibitors Fact Sheet 470 : other antiretroviral drugs in development Fact Sheet 480 : immune therapies These drugs have not been approved by the Food and Drug...

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HIV and mucous membrane exposure

I work at a pediatric clinic. Today after I centrifuged some blood from a 17 year old black male I was putting it into cryovials. I am not sure but I think I may have splashed some in my eye. The pipette I was using had formed a bubble on the end...

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation

Hello,All occupational exposures (or potential exposures) should be reported to the appropriate division of your laboratory/medical facility so that an evaluation of risk to bloodborne pathogens can be undertaken and treatment offered if warranted.... Read more »

Mucous membrane exposure with dried blood.

I know that supposedly HIV is inactivated when blood dries. I had a little blood on my gloves at work. I had to wipe my nose immediately because it was dripping, so like an idiot I grabbed a tissue and wiped my nose without thinking that I had...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

There has never been a documented transmission after an exposure on the order of what you described. The CDC reported many years ago three cases of mucous membrane exposure or skin exposure after impressive contacts with the blood from AIDS... Read more »

Mucous membrane exposure of HCW

Hi Dr. Frascino - Just wanted to write and tell you what an asset you are to the HIV community. Thank you for your guidance and sharing your knowledge. I am an RN that was recently exposed to unknown source blood by a bloody water splash to the face...

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation

Hello Healthcare Worker,First off, I hope you filed an incident report with your supervisor at the ER. The CDC's most recent update on Management of Occupational Exposures can be found at www.cdc.gov/mmwr/preview/mmwrhtml/rr5011a1.htm.... Read more »

Mucous Membrane infectivity

I have read recently that scientist have learned that HIV does not need a cut or abrasion to permeate mucous membrane. I believe it was a result of test they did on monkeys where they were exposed to HIV on the back of their mouths. Most ended up...

Response from Rick Sowadsky, M.P.H.

Nevada State Health Division AIDS Program

Hi. Thank you for your question. The study you are talking about usingmonkeys, was a study used to confirm (in a laboratory setting), clinical casereports of HIV transmission through giving oral sex. The results of thisstudy confirmed these... Read more »

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Mucous membrane question

Posted by Anonymous, 1 Reply

I have a question I hope someone or many people can answer:

Is the entire lip a mucous membrane or just the inside of the lip a mucous membrane? Or is the lip not a mucous membrane at all?

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Fusion Inhibitor News?

Posted by Anonymous

Does anyone know if the fusion inhibitor trials (phase III) are going OK, or where to go for an update? Last I heard 700 patients in 100 countries were in the study for T-20(?)
I went to the Trimeris site and didn't see anything new.

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Can HIV be transmitted through nose-mucousmembrane

Posted by madeinkorea, 1 Reply

Hi All,
Can HIV be transmitted through nose mucous membranes?
My exposure was, accidental nose picking with unknown person's blood in my fingers? Only after the nose picking incident I realized that the person I had handshake was bleeding and I was... Read more »

Quick Question.. What can you tell me??

Posted by limon12, 1 Reply

I know that the mucous membranes of the genitals are susceptible to HIV transmission but just how easily can infected blood enter your blood stream from contact with the tip of your penis through the urethra membrane? (No cuts or rashes on penis,... Read more »

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