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Hiv Medications And Lipodystrophy

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AIDS InfoNet

Body Shape Changes (Lipodystrophy)

No researcher has suggested that people with lipo should stop taking ART. What Causes Lipo? We do not know what causes lipo. There are different causes for fat loss and fat gain. Fat Loss Zidovudine (Retrovir, AZT) and stavudine (Zerit, d4T) are linked to fat loss. Efavirenz (Sustiva) may also contribute. Fat Gain One theory is that protease inhibitors interfere with the body's processing of fat. However, some patients who have never...
Ask the Experts

Lipodystrophy (LIPODYSTROPHY)

I'm trying to find CURRENT information about lipo treatment options, but everything I find, including on this site, is over 2 years old. Can you point me to anything newer. I've been advanced/full-blown (technically) for 15 years, and...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hi,The best source for current information about lipodystrophy (lipoatrophy and lipohypertrophy) should be your HIV specialist physician. Treatment options depend on your specific case. There is current information on treatment options on this site... Read more »

afraid to start medication because of lipodystrophy

my first lab cd4 331 with 23 % cv 16600, my second cd4 407 with 26% cv 40000, tomorrow I have appointment to see the third lab resoult but I am afraid that the doctor is going to tell me again that is time to start medication (atripla already...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
Hello and thanks for posting. Even though the recent guidelines have recommended earlier initiation of antiretroviral therapy, one should only start antiretroviral treatment when fully prepared. There is a legitimate concern about the risk of... Read more »

lipodystrophy and current medications

I have been on Atripla and Zidovudine for the last three years and have noticed an increase in the effects of lipodystrophy and lipoatrophy. Specifically, the bull hump is more noticeable and the wasting of the face is more pronounced.Which of the...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Of the drugs you mention the zidovudine ( a thymidine analogue) has been most linked to fat redistribution issues (fat loss > fat gain). Time with HIV, age, CD4 nadir, genetics, and other non-drug factors also contribute to fat distribution... Read more »

HIV Treatment & Lipodystrophy

Hi Doctor,I been on medication of Combivir + Stocrin since 2006. I recently found out that this regimen is contributing to lipodystrophy. I am quite concern about this and wonder is that any alternative treatment I can consider? I plan take some...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
If available to you a switch from Combivir to Truvada (or Epzicom if HLA B5701 negative) often will slow/reverse fat loss. Effects on fat gain are more variable. Exercise and diet may help some patients so you should continue those healthy... Read more »
Connect With Others

lipodystrophy

Posted by Anonymous
hello, i'm a freelance reporter and I'm trying to write a story for POZ magazine on the condition lipodystrophy. if you're currently on medication and have been impacted by this, please email me at edyer@post-gazette.com.
leave a phone number where... Read more »

lipodystrophy

Posted by Anonymous, 2 Replies
I have been taking AIDS medications for ten years now and my health is much better than it use to be, but it has caused one side effect that really has really effected my self esteem and causes me to have serious bouts of depression. My stomach has... Read more »

Lipodystrophy and/or Neuropathy?

Posted by Anonymous, 2 Replies
Is it possible to experience lipodystrophy and neuropathy within 2-3 months of HIV exposure, or are these conditions generally symptomatic of long-term HIV status? I have noticed significant swelling under my arm/ beside my right breast. I'm not... Read more »

Lipodystrophy or Neuropathy?

Posted by Anonymous, 1 Reply
Is it possible to experience lipodystrophy and neuropathy within 2-3 months of HIV exposure, or are these conditions generally symptomatic of long-term HIV status? I have noticed significant swelling under my arm/ beside my right breast. I'm not... Read more »