Hiv Helper T-cells

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Articles

T Follicular Helper Cells and HIV

T follicular helper cells (TFH) are a subset of CD4 T cells that reside almost exclusively in the lymph nodes, where they specialize in helping B cells generate antibodies. In a testament to the complexity and difficulty of studying the immune... Read more »

HIV Replication and Persistence in T Follicular Helper Cells

Following up on the recent post on T follicular helper cells(TFH) , a study published on December 17th in the Journal of Experimental Medicine reports that TFH represent a major site of HIV replication andpersistence. The finding is not... Read more »

Attack of the Killer Helpers (Part Two)

Among the many tasks of the immune system, the responsibility for recognizing and killing virus-infected cells largely falls to the subset of CD8 T cells designated cytotoxic T-lymphocytes (CTL). The question of whether CD4 T cells (traditionally... Read more »

Ask the Experts

Injected helper t cells to rebuild immune system?

Sir Bobby,Real quick. What about injected helper t cells in combination with hiv medicines to prevent aids from happening? Or what about inject helper t cells as a shot during treatment iterruptions? What do you stay?Please stay well till your...

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation

Hey Ben,Immune-based therapies have been strong areas of research for quite some time. I did experiments like the ones you proposed in the early nineties. I stimulated T-cells with Interleukin-2 (a T-cell growth factor), grew and expanded T-cell... Read more »

PML and low helper cells

I was diagnosed with PML in February 2000 after comparing the results of an MRI in December 1999 and January 2000. My neurologist has only seen 2 other cases of PML which were further in the disease progression than I appear to be. He and my HIV...

Response from Judith Feinberg, M.D.

University of Cincinnati, College of Medicine

You're already doing what you can to improve your T cells by taking combination therapy for HIV. Some people have a slower rise in T cells than others, and although you haven't had the fastest possible rise, a slow and steady one will... Read more »

Helper T-Cells

I've read that non-progressors produce certain type of "T helper Cells" in enough quantity so as to contain the virus, while progressors produce the same kind of "T helper Cells" but not in enough quantity. Has anybody...

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine

The cells you are referring to I believe are the CD8 cytotoxic t cells. This type of cell is the primary containment mechanism of HIV replication. The mechanism by which these cells contain replication is the subject of intense research. Infusing... Read more »

Helper T Cell Rebound Following Chemotherapy

I recently completed a course of chemotherapy (2 cycles of Mytomycin C and 5FU) and radiation therapy (6 weeks) to treat squamous cell carcinoma. I have been HIV positive since 1985 and my CD4 levels have always been in the 500-600 range....

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine

A reduction in CD4 counts is commonly seen with chemotherapy or radiation therapy. Only time will determine whether you will get up to your pretreatment levels. It can take weeks to months to recover counts. I have seen it both ways in my practice.... Read more »

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Do anybody know about CD4 cells count?

Posted by Anonymous, 1 Reply

Hi guys,

I have a question about my tests - in fear of HIV infection because of a bad incident and symptoms not long after, I went to have my blood tested for HIV as well as other infections - the PCR and antibody test both turned out Negative, but... Read more »

stem cell

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July 6, 2006 News Content
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positive or negative?

Posted by wasek, 1 Reply

Once HIV gets into the body, it passes instructions into T helper cells on how to make more HIV. These instructions are known as "provirus". Later on the infected T helper cell turns into a factory that can make HIV.
My questions are:
1. "how to know... Read more »

New Virus Leads Drugs to HIV-Infected Cells

Posted by new2this2010

This is great news.

http://www.dailytech.com/New+Virus+Leads+Drugs+to+HIVInfected+Cells/article22391.htm#cmt706319 Read more »

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