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Hiv Gp120

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Get the Facts
San Francisco AIDS Foundation

How HIV Damages the Immune System

Introduction HIV Targets T Cells HIV Takes Control of T Cells HIV Replicates Introduction The basic structure of HIV is similar to that of other viruses ( Figure 1 ). HIV has a core of genetic material surrounded by a protective sheath, called a capsid . The genetic material in the core is RNA (ribonucleic acid), which contains the information that the virus needs in order to replicate (make more copies of itself) and...
Ask the Experts

Block gp120 on CD4 instead of attacking HIV?

Hi, I'm not an expert in virology, and I have a VERY limited understanding of the HIV infection mechanism; I was wondering however why we try and attack the HI Virus. Why not rather the CD4 receptors to the gp120 protein on the virus instead (if it...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
There is already one fusion inhibitor (fuzeon) on the market, and others in clinical trials. Blocking the virus from attaching to cells is the subject of intense research and drug development. Read more »

dc-sign

...the discovery of dc-sign as the initial connection with hiv gp120 - dc signs are only present on the surface of dendritic cells on mucosal linings. Does this mean that it might be almost physiologically
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
I think we are just beginning to learn about this important receptor on dendritic cells (DC). It facilitates the interaction of CD4 and other coreceptors that are necessary for HIV entry into cells. We don't know if all DC in all tissues have this... Read more »

banana and hiv

Doctor Bob what do you think about using squeeze banana as lubricant since scientist found something that can kill hiv in banana, in short rubbing banana on condom to reduce risk in case of breakage.tugurun
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hi,There has always been something appealing (pun intended) about a banana-flavored condom. However, using squished banana on a condom as a lubricant will not help prevent HIV. Research into Ban-Lec, the banana-derived protein that may help block... Read more »

How to stop HIV

The hiv virus uses the gp120 and gp41 to attach itself to the CD4 cells for replication. Has there been any study done on possible disabling/distruction of the gp120 and gp41 arm on the virus to prevent attachment to the Cd4 cells?
Maribel Rodriguez-Torres, M.D.

Response from Maribel Rodriguez-Torres, M.D.

Fundacion Gatroenterologia De Diego
Yes.There is continuos research on the different sites for entry of the virus to the cell. This avenues have been explored in the hope to develop additional therapies. Read more »
Articles
U.S. National Institute of Allergy and Infectious Diseases

Scientists Unveil Piece of HIV Protein That May Be Key to AIDS Vaccine Development

..."This elegant work by Dr. Kwong and his colleagues provides us with a long-sought picture of the precise interaction between the HIV gp120 surface protein and this neutralizing antibody," says NIAID Director Anthony S. Fauci, M.D. "This finding... Read more »
National Institute of Allergy and Infectious Diseases

New Findings Suggest Strategy to Help Generate HIV-Neutralizing Antibodies

New discoveries about anti-HIV antibodies may bring researchers a step closer to creating an effective HIV vaccine, according to a new paper co-authored by scientists at the Vaccine Research Center of the National Institute of Allergy and... Read more »
U.S. National Institute of Allergy and Infectious Diseases

"Trojan Horse" Virus Controls HIV Infection

...destruction by the body’s immune system by displaying HIV’s outer coat protein. But this protein, HIV gp120, is the same one that attaches to the T-cell receptors and leads to ... Read more »
International AIDS Vaccine Initiative

First Positive Results From Large-Scale HIV Vaccine Trial

Results from an AIDS vaccine trial known as RV144 involving more than 16,000 participants from Thailand show that a prime-boost regimen of two genetically engineered vaccine candidates demonstrated marginal but statistically significant protection... Read more »
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time line

Posted by Anonymous
email this page to a friend your email @ friend's email @ brief messsage send page subscribe to the FRONTLINE bulletin Get FRONTLINE's updates & behind the scenes newsletter your email subscribe ... Read more »

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Green tea?

Posted by franfrog
Green Tea Blocks HIV in Test Tubes Too Soon to Know if Green Tea Will Do the Same in People By Miranda Hitti WebMD Medical News Reviewed By Ann Edmundson on Thursday, May 25, 2006 May 25, 2006 -- An antioxidant in green tea may block... Read more »

REVIVO

Posted by Anonymous, 5 Replies
Any of you knows whether the claims in www.natureproducts.net on the efficacy of Revivo against HIV are plausible? I ordered a month's dose out of desperation when i was diagnosed back in July 2003 and took it (am treatment naive). My VL dropped... Read more »