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Hiv Fusion Inhibitors

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Test Positive Aware Network


... Common Name: enfuvirtide or T-20 Brand Name: Fuzeon Class: HIV fusion inhibitor (a type of entry inhibitor) Standard dose: One subcutaneous (under the skin) injection of 90 mg (1 ml) twice daily (every 12 hours) into the upper arm, thigh or abdomen. Can be taken with or without food, with no food
Ask the Experts

How good is this new hiv drug ???

Hi Dr Keith, how good is this new hiv drug ????thank you for your timeRossPanacos Pharmaceuticals announced yesterday that it has sold its first-in-class HIV maturation inhibitor bevirimat to Myriad Genetics, a biotechnology company that is also...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Bevirimat has shown moderate activity for the treatment of HIV infection including for virus which is resistant to the current HIV meds. Development is still early. For most HIV practices in US the currently HIV medications are usually working... Read more »


Hiya Experts, Thank you for you work as always. I was wondering what are the next five hiv drugs that will be approved? What should we the public keep our eyes on? When can we expect these? And most importantly, do these drugs offer hope to...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
...are near approval-In the next 6 months:Extended Release stavudine (Zerit XR)- a once-daily verson of stavudineT-20- the first HIV fusion inhibitorIn the next 1-2 years (hopefully)-Atazanavir - a once daily protease inhibitorGW908- an improved... Read more »

Leading Edge Study for Recently Infected

Dear Doctor(s), Many recently infected people visit this web site. Some may wish to save their HIV-1-specific immune response (assuming that they are not long-term non-progressors). Below is some detail of a study that I wish I could enroll in,...
David Wohl, M.D.

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill
Hi Tom-Thanks for the heads-up about this study. It is important to note that this particular trial is enrolling patients who are receiving most forms of HIV therapy and have viral loads that are undetectable. There is no requirement that... Read more »


what is fusion inhibitors
Carol Salisbury, APRN-BC, MSN

Response from Carol Salisbury, APRN-BC, MSN

Michigan State University College of Nursing
Hi , A fusion inhibitor works on the HIV virus to prevent it from entering the T-cell. It binds to part of the virus call the GP-41. Once contact has been made with the virus on the T-cell, infection occurs rapidly. Fuzeon prevents this process. ... Read more »
Seattle Treatment Education Project

A New Type of Anti-HIV Drugs: Fusion Inhibitors

The fusion inhibitor that is the furthest along in development is called T-20. It interferes with HIV entering a cell by binding to part of the HIV envelope. Why Do We Need New Anti-HIV Drugs? It is well known by persons with HIV, their... Read more »
U.S. Centers for Disease Control and Prevention

Long-Term Treatment With Subcutaneous T-20, a Fusion Inhibitor, in HIV-Infected Patients: Patient Satisfaction and Impact on Activities of Daily Living

Currently, all approved agents for HIV therapy target one of two viral enzymes: reverse transcriptase or protease. Clinical studies have shown that current agents are highly effective when used in combination; however, many patients are unable to... Read more »
Treatment Action Group

TAG at Ten: The Year 2002

...nominated as NIH Director. TAG meetings at OAR, NIH. 3rd International STI Workshop, MontrĂ©al. April: Meeting on Roche/Trimeris HIV fusion inhibitor, T-20 (Chicago). TAG meets UNAIDS director Peter Piot, is critical of slow-moving UN system.... Read more »
Gay Men's Health Crisis

The Coming Crisis

The last few years have witnessed remarkable progress in treating people with advanced and drug-resistant strains of HIV. Four powerful drugs became available that either overcame drug resistance (Prezista [darunavir, TMC-114], Intelence... Read more »
Connect With Others

Am I Infected

Posted by delhiguy, 3 Replies
I am 30 YO guy. Worried that I may have got infected. I met this friend of mine on 5th of Dec 2010 which was just a causual meeting after 5 years. After having drinks she started touching me and I got aroused and we end up mating. While in act, she... Read more »

Problems with HIV Science

Posted by Anonymous, 3 Replies
By Matthew Irwin, MD The author, a family practice physician in Washington, DC, reviews the evidence that has led him to the conclusion that the HIV=AIDS hypothesis is fundamentally flawed. Disagreement about HIV's role in causing AIDS has... Read more »


Posted by Anonymous, 1 Reply
Exploring: NIAID, NIH, U.S. DHHS March 2005 HIV Infection and AIDS: An Overview INTRODUCTION AIDS (acquired immunodeficiency syndrome) was first reported in the United States in 1981 and has since become a major worldwide epidemic. AIDS is caused... Read more »

can anyone tell me

Posted by Anonymous, 7 Replies
why does carolyn salisbury say you need to test up until 12 months and you guys say 3 months? She is on ask the expert board. please I need details to why Read more »