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Hiv Fusion Inhibitors

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AIDS InfoNet

Fusion and Attachment Inhibitors

Note: Several fact sheets describe drugs that are being tested against HIV: Fact Sheet 410 : nucleoside analog reverse transcriptase inhibitors (nukes) Fact Sheet 430 : non-nucleoside analog reverse transcriptase inhibitors (NNRTIs or non-nukes) Fact Sheet 440 : protease inhibitors Fact Sheet 470 : other antiretroviral drugs in development Fact Sheet 480 : immune therapies These drugs have not been approved by the Food and Drug...
Ask the Experts

Fusion and entry inhibitors

Dr. Young: Hi. When several of the fusion and entry inhibitors become a reality for HIV treatment will these agents be taken combination as HAART is today? And will these treatments have a lower toxcidy and resistant profiles than HAART or is it...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for your question.Fusion (or entry) inhibitors should make their debut in the near future with the release of enfuvitide (nice name, huh--otherwise known as Fuzeon or T-20). The class of medications is exciting from the perspective that many... Read more »

Fusion inhibitors and clinical trials.

I have recently reached the point where I need to start taking anti-HIV medications and I am seeking your advice on how to proceed.Our local AIDS Clinical Trials Unit needs people who are treatment-naive for a study involving fusion inhibitors in...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
I think that your primary ID doctor is correct. A simple regimen would probably work as well with fewer side effects. Fusion inhibitors require daily injections and are no walk in the park. If you do decide to participate in this trial you should... Read more »

mechanism of action of fusion inhibitors

how do fusion inhibitor act to treat HIV...
Don Kurtyka, ARNP

Response from Don Kurtyka, ARNP

University of South Florida School of Medicine
There's a ton of information on thebody.com that describes how fusion inhibitors work. You might want to also check out www.fuzeon.com.If you're more into graphics, check out the video link in this message! It's very cool. <a... Read more »

Fusion Inhibitors

Can you tell me what a fusion inhibitor exactly is and decribe how it works in the body?...
Don Kurtyka, ARNP

Response from Don Kurtyka, ARNP

University of South Florida School of Medicine
Fusion inhibitors are a subclass of drugs called entry inhibitors. Unlike previous HIV medications that target HIV once it attacks and infects a T-cell, entry inhibitors prevent HIV from being able to attach to a T-cell. By keeping HIV from... Read more »
Connect With Others

Fusion Inhibitor News?

Posted by Anonymous
Does anyone know if the fusion inhibitor trials (phase III) are going OK, or where to go for an update? Last I heard 700 patients in 100 countries were in the study for T-20(?)
I went to the Trimeris site and didn't see anything new.

Read more »

lipodystrophy from protease inhibitors

Posted by Anonymous, 4 Replies
I have known about my HIV+ status now for 6 years, and God has blessed me with continued good health. I have accessed all the major medications, plus vitamins to help fight the disease. Once I started taking the new protease inhibitors, I started... Read more »

Integrase Inhibitor

Posted by Survivor
I just wanted people realize there is hope and continued very active DRUG DISCOVERY!

Merck, Gilead Release Strong Findings From Clinical Trials of Experimental Integrase Inhibitor Antiretroviral Drugs

Whitehouse Station, N.J.-based Merck and Foster... Read more »

Protease Inhibitors - Hemophilia bleeds

Posted by akcol
Hi, my fiance is a Long Term NonProgressor - 24 years positive, co-infection HCV, with severe Hemophilia A.

This is a question for the gentlemen with Hemophilia please.
We're requesting any input about any Hemophilic PI increased unusual bleed... Read more »