Hiv Entry Inhibitors

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Articles

Wall Street Journal Examines Pharmaceutical Companies' Efforts to Develop HIV Entry Inhibitors

The Wall Street Journal on Wednesday examined how several pharmaceutical companies are "rushing" to develop antiretroviral entry inhibitor drugs, which "block" HIV before it enters human cells rather than fighting it once inside the cells. Entry... Read more »

Phase II Trial Shows Tanox's Experimental Entry Inhibitor Lowers HIV Viral Loads in Treatment-Experienced Patients

Houston-based pharmaceutical company Tanox on Wednesday released the results of a Phase II clinical trial that showed its experimental entry inhibitor TNX-355 lowered HIV viral loads after 24 weeks better than a placebo, the Wall Street Journal ... Read more »

Fuzeon: A Review of the First Entry Inhibitor

This material was developed independently through an unrestricted educational grant from Trimeris. Fuzeon (T-20, enfuvirtide) is the first in a new class of anti-HIV meds called fusion inhibitors (also known as entry inhibitors). Fusion... Read more »

Ask the Experts

Fusion and entry inhibitors

Dr. Young: Hi. When several of the fusion and entry inhibitors become a reality for HIV treatment will these agents be taken combination as HAART is today? And will these treatments have a lower toxcidy and resistant profiles than HAART or is it...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Thanks for your question.Fusion (or entry) inhibitors should make their debut in the near future with the release of enfuvitide (nice name, huh--otherwise known as Fuzeon or T-20). The class of medications is exciting from the perspective that many... Read more »

Why All The Excitment About Entry Inhibitors?

Dr. Young: Hello. Why is there such excitement with entry inhibitors? Will T20 and T1249 later to be just as infective for many HIV infected as HAART has? Sorry if I sound too cynical, but the past is littered with much hearlded HIV "magic...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Anytime a new class of drugs shows promise, there is a lot of interest and excitement.Such is the attention that entry inhibitors have received over the past several years. The first drugs of this class to see human trials were the inhibitors T-20... Read more »

Entry Inhibitors/Future

Dr. Wohl, First off, happy new year. I hope that 2006 brings some exciting developments in the treament of HIV. Hopefully something that is very difficult to get gain resistant to and is easy on the body. That said, do these entry inhibitors really...

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill

Happy New Year to you.2006 may be a little shy of revolutionary new therapies (sorry). It IS likely we will see a new protease inhibitor (TMC114) which looks like it will be helpful for people with resistant virus.What we really can use is a second... Read more »

entry inhibitors

Hi.What's the difference between a fusion inhibitor and an entry inhibitor? I've seen both terms used.Thank you....

Response from Don Kurtyka, ARNP

University of South Florida School of Medicine

The term "entry inhibitor" refers to the entire class of agents that prevent HIV from entering the CD4+ cell. Fusion inhibitors (like Fuzeon) are one type or category of entry inhibitor. Other types / categories include chemokine... Read more »

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Connect With Others

Entry Inhibitors

Posted by Anonymous, 1 Reply

Does anyone know anything about the new entry inhibitors? I think Pfizer and Schering both have drugs in development. Should we be hopeful? Read more »

Entry into the US if HIV+

Posted by ScotCharles, 2 Replies

Amazingly, there is something that prevents people who self-disclose their HIV status from entering the US. I have never been asked this question since I hold both US and British passports and have a French work permit. So who am I to talk?

What is... Read more »

I have been reading the entries for hours

Posted by Anonymous

I have been reading the entries on this page for two hours now.
The possibility and/or probablilty of HIV/AIDS is overwhelming at
first, then bearable as you become aware of what you can and
cannot do to go on with your life. I am not positive, but... Read more »

Travel: Entry into US from Canada

Posted by Anonymous, 5 Replies

Hello everyone. I was diagnosed positive just last weekend. After initial shock, now I'm trying my best to cope with reality. One important thing is: my parents live in the States (I'm in Canada). I'm a Canadian national. How possible is it for me... Read more »

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