Hiv Atripla And Joint Problems

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Get the Facts

Atripla (Efavirenz + Emtricitabine + Tenofovir)

What Is Atripla? Atripla is a tablet that contains three antiretroviral drugs (ARVs) used to fight HIV: efavirenz (Sustiva), emtricitabine (Emtriva), and tenofovir (Viread). Atripla is manufactured by Gilead and Bristol-Myers Squibb. It is the first tablet that includes a complete antiretroviral regimen. A generic version was approved for sale outside the U.S. under the PEPFAR program (see Fact Sheet 475 ). The drugs in Atripla are a...

Ask the Experts

ATRIPLA and Avascular Necrosis/Joint Pain

I am 43-tr old gay male with HIV. I was started on Sustiva/Truvada/Combivir in 2003 when I was diagnosed. Within 3 months, my viral load went to undetectable and has remained there. In 2006, I was switched to Atripla, which is a fixed dose...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

There is anecdotal level assocaition of Atripla with avascular necrosis of the femur but no clear signal has emerged from numerous clinical trials and observational data basis. Tenofovir has been linked to bone problems (osteoporosis and... Read more »

joint pains associated with atripla

I have been on atripla for 4 years now and wonder if it can cause problems with joints in legs, hips and hands as i have expeinced arthritis like symptoms in my hands and popping hips and grinding sounds in knees....

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

To my knowledge the components of Atripla have not been clearly linked to polyarticular arthritis involving the large joints (arthritis is fairly common in general population so can be hard to link a drug to such symptoms in isolated cases). I would... Read more »

hiv+extremely overweight with joint problems

i am 46yrs. old weighe270lbs. and 6'1" tall.I have avascular necrosis[a.v.n.]have had one hip replacement three yrs. ago and wwill in the near future will need the other one replaced.I am on a four drud regimen of H.AR.T.medications.Where...

Response from Nelson Vergel, B.S.Ch.E., M.B.A.

Program for Wellness Restoration

You say you feel out of breath and weak. Are you taking Zerit, Videx or Hivid? If so, have you got your lactate levels checked for lactic acidosis? Increased lactic acid caused by mitochondrial toxicity generated by nucleoside analogs can cause... Read more »

Joint pain with Atripla

I have recently switched to Atripla and have coincidentally developed sever ankle joint pain 1 month into the therapy. There was no other apparent cause or injury for the paint to develop. The pain is so severe that it is difficult to walk...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Localized joint pain from Atripla as you describe is not common so an evaluation for other causes with full history, physical examination and possibly blood tests/X-rays would be recommended in order to sort out the possible cause and then to devise... Read more »

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Joint pain and Skin problems

Posted by Anonymous, 1 Reply

Does any one know the correlation between pain in the joints and skin conditions such as subheroic dermititis to HIV. My contact was about a year ago (protected sex with an escort) and for the last 6 months I have had rashes and pain in the various... Read more »

Achy Joints from my meds......

Posted by harcase116, 4 Replies

I would like to know what would be the best thing for me to deal with my achy joints, I take Atripla don't have too much side effects from it just the ache joints! I have been taking over the counter pain medicines but it has not help ! Read more »

Have HIV and on Atripla with a question

Posted by Starboy, 4 Replies

Hi All:
I have been on Atripla since it first came out and recently notice that I seem to be not allergic to Poision Ivy anymore. Was wondering if any one else has a similar experience. I have been working in my woods all week in Poision Ivy which I... Read more »

Joint Pain caused by liver, HIV, meds, arthritis?

Posted by ScotCharles, 3 Replies

Has anyone experienced joint pain that was diagnosed as relating to either HIV or the meds? Don't laugh now, but my elbows are warm to the touch, and I have a burning pain in them. I have liver problems which cause my right shoulder and the right... Read more »

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