Hiv And Salvage Therapy

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Salvage Therapy

What Is Salvage Therapy? Antiretroviral therapy (ART) sometimes needs to be changed if the treatment is not working. This usually happens when the HIV viral load (see Fact Sheet 125 ) rises instead of staying very low. A rise in viral load almost always means that HIV has developed resistance (see Fact Sheet 126 ) to the antiretroviral drugs (ARVs) someone is taking. When HIV begins to increase even when someone is taking ART, this is known as...

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Long term "salvage" therapy side effects

I am a person who has been hiv+ since the 80's and was one of the first people to get the hiv antiblody test after its release. I started meds soon after there was something available besides AZT, due to a random CD4 count of 30. I then began...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Great question for which there is no good answer other than--watch closely since patients like yourself are the real laboratory for what happens over the long term. As I tell patients - no lab rat has taken those meds for as long as some of our... Read more »

salvage therapy

I am a doctor based in zambia who treats HIV pateints and i have been placed in a quagmire of sorts. i recently saw ayoung man of 15 years age who is on ARV for close to 10 years. he unfortunately is resistant to a whole range of drugs . he had both...

Response from Renslow Sherer, M.D.

University of Chicago Hospitals

This is a difficult situation that is increasingly common in resource poor settings. This young man has had more access to ART and diagnostic tests than most, but the information may well be incomplete and out of date by this time. Complex... Read more »

salvage therapy

Dear Sir: I have doubts in the management of an AIDS patient. She is a 41 yo patient who is HCV and HIV (+) since 1995, having used many antiretroviral drugs in the last years.At this moment she presents a multidrug...

Response from Sharon Lee, M.D.

University of Kansas Medical Center

This patient has a very difficult resistance pattern to work around. She has lost the non-nucleoside class with the K103 and L100 mutations, knocked out zidovudine and stavudine with the 210 and 215, and of course lamivudine and emticitabine with... Read more »

Salvage Therapy Please Help

What salvage treatments can be started for a patient with Cryptococcal meningitis, CD4s of 8, a Viral Load over 100,000, off therapy for six months because of wasting that may have been caused by meds?weight returned from about 129lbs. to 160lb...

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast

There are two inter-related aspects to consider in your situation. The first is management of refractory cryptococcal meningitis and the second is management of drug-resistant HIV. When the HIV infection is brought under control this usually leads... Read more »

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Changing drug therapy

Posted by Anonymous, 1 Reply

I have been HIV+ for 12+ years and have never had a T4 count above 400 and have been as low as 128. I have never had any oportunistic infection or HIV related illness.
Current treatment includes Combivir & Crixivan. Current viral load 2043 and... Read more »

Resistant, then what? How many lines of therapy?

Posted by Anonymous, 3 Replies

What percentage of folks infected with HIV are basically screwed by total resistance right out of the gate? I know resistance forms of HIV is becoming more common, but generally there is still a line of treatment options that will work for these... Read more »

hiv gene therapy

Posted by hopefulone, 2 Replies

hiv gene therapy has been getting a lot of play in the national and international press as of late....i would be interetested in comments on this hope. Read more »

Kill HIV with Photopheresis, Ultra-Violet Blood Irradiation (UBI) Therapies?

Posted by Jon316, 1 Reply

I've read a little about Photopheresis and Ultra-Viole Blood Irradiation (UBI) therapies being performed by M.D.'s across the U.S., Europe, Russia and Germany. It seems that these procedures have been done for quite some time, but fell out of... Read more »

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