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Hiv And Protease Enzyme

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AIDS InfoNet

Protease Inhibitors in Development

These drugs have not been approved by the Food and Drug Administration (FDA) for use against HIV. Protease Inhibitors These drugs block the protease enzyme. When new viral particles break off from an infected cell, protease cuts long protein strands into the parts needed to assemble a mature virus. When protease is blocked, the new viral particles cannot mature. Protease Inhibitors in Development Several firms are trying to develop a new...
Ask the Experts

Papaya enzymes with protease

I am currently taking a papaya enzyme supplement for digestive purposes. Just noticed it also contains protease. Does this affect my HIV status in any adverse way?...
Cade Fields-Gardner M.S., R.D.

Response from Cade Fields-Gardner M.S., R.D.

The Cutting Edge
There are many "proteases" in foods, your intestine, and supplements. It is a catch-all category of enzymes that break apart proteins. In this case, your papaya supplement has these enzymes that have an effect to break apart dietary... Read more »

Protease Enzyme

First of all, I am HIV+ and NOT currently taking any antiretrovirals. I recently had some stomach problems, nausea, diarrhea, etc. A friend recommended a blend of natural enzymes and probiotics. When I checked the label I noticed that it listed...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Steve in DC, thanks for your post.Humanities aside, the proteases that you're talking about are different than HIV protease. Indeed, there are many different proteases out there.While I'm not a huge fan of supplement pills (I favor eating... Read more »

dietary protease vs HIV protease

My mother who is a dietician feels my regimen of Kaletra, Invirase and Truvada is interfering with fat absorption. She feels this is why PI's seem to result in smelly or loose stools. Her solution, dietary enzymes which contain the...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
What you are describing is a combination of enzymes produced by the pancrease to facilitate digestion and absorption of food from the gut. If there is pancreatic insufficiency then those enzymes are given in pill form and that is often helpful. I... Read more »

HIV protease inhibitors

Could you tell me the spectrum of activity and the mechanism of resistance for the antimicrobial HIV protease inhibitors (Ex: Indinavir)and do they work with gram positve/gram negative bacteria. What bacteria does it work against. Or what sites I...
Eric Daar, M.D.

Response from Eric Daar, M.D.

UCLA School of Medicine
The HIV protease inhibitor selectively blocks the protease enzyme and prevents an infected cell from producing infectious HIV. Resistance develops when mutations emerge in the viral protease enzyme that prevent the inhibitor from interacting with... Read more »
Connect With Others

are enzymes related to hiv testing?

Posted by Anonymous, 1 Reply
I was wondering if when you donate plasma and they test your enzyme levels in your liver and stuff does it have to do with hiv.I'm wondering becuase i was told my enzyme levels were low when they tested my plasma and they needed to take 2 tubes of... Read more »

lipodystrophy from protease inhibitors

Posted by Anonymous, 4 Replies
I have known about my HIV+ status now for 6 years, and God has blessed me with continued good health. I have accessed all the major medications, plus vitamins to help fight the disease. Once I started taking the new protease inhibitors, I started... Read more »

Abbott pharmaceuticals price gouging protease inh

Posted by BabyPeanut
Editorial, The Center for AIDS (12/15/03)

In a move that startled healthcare professionals and community members alike, Abbott pharmaceuticals announced a price increase of almost 500% for its protease inhibitor ritonavir (Norvir). Norvir is widely... Read more »

Protease Inhibitors - Hemophilia bleeds

Posted by akcol
Hi, my fiance is a Long Term NonProgressor - 24 years positive, co-infection HCV, with severe Hemophilia A.

This is a question for the gentlemen with Hemophilia please.
We're requesting any input about any Hemophilic PI increased unusual bleed... Read more »

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