Hiv-2 Genome

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Articles

UNC Researchers Decode Structure of an Entire HIV Genome

The structure of an entire HIV genome has been decoded for the first time by researchers at the University of North Carolina at Chapel Hill. The results have widespread implications for understanding the strategies that viruses, like the one that... Read more »

Africa Could Miss Out on Rewards of Genome Research Without More Funding to Study HIV, Malaria, TB, Scientists Say

Scientists meeting in Nairobi, Kenya, on Monday at the start of a four-day conference -- titled "A Time to Heal: Cracking Africa's Killer Diseases " and sponsored by the Africa Genome Education Institute -- "warned" that Africa could "lose out" on... Read more »

Researchers Decode HIV Genome

"Researchers at the University of North Carolina at Chapel Hill have decoded the entire HIV genome, opening the door to understanding how viruses infect humans -- knowledge that could lead to new antiviral drugs," the Triangle Business Journal ... Read more »

Ask the Experts

Many mutations listed on my Genome/Phemone Test

Hello Dr. Sherer,I just received my Genome/Phenome Test back and found that I have the K103N mutation so my Dr. took me off Atripla and put me on Truvada and Intelence. At the end of the test, it also gave a complete listing of Mutations Detected...

Response from Renslow Sherer, M.D.

University of Chicago Hospitals

Of the 32 mutations that you list, only 8 - 2 NRTI mutations and 6 PI mutations - are known to be (or, in two cases, may be) associated with reduced sensitivity to drugs in those classes. The remainder of the mutations are 'polymorphisms'... Read more »

re:Ok

Hi Dr.Yes Professor Venter said that in the context of the advances from the Human Genome Project. "Perhaps as we study the genetic structure of the virus we will learn it's weaknesses and stop it." That is how the NNRTI were...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

I'm not sure what your question here is, but yes, the NNRTI and protease inhibitor classes were developed through an understanding not only of the genetic structure, but the atomic structure of the drug targets. The problem it seems, though is... Read more »

hair thinning

I was just diagnosed 3-23-10, and my tcell count at 600 and my vrl load at 1400..im on atripla1/day and isentress 2x daily till my genome comes back....could the thinning of hair have anything to do with it? Its not a lot of hair loss at all, but i...

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine

It is unlikely that HIV or those meds would be causing hair loss. Assuming you are male and older, than male pattern baldness (your underlying genetics) is the most likely. Other things like low thyroid function could be causing it as well.... Read more »

Geno test

What is the proper term of "Geno test"?...

Response from Renslow Sherer, M.D.

University of Chicago Hospitals

A 'geno' test is a genotype, i.e. a test that literally describes the main parts of the HIV genome. When the test shows no resistance mutations, we refer to it as 'wild type'. When the genotype shows one or more mutations, we... Read more »

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New treatment approach to HIV: trial announcement

Posted by Anonymous

We've applied for patent protection on a novel treatment approach to HIV using existing medications already FDA-approved for other disease indications. We hope our approach will decrease infectivity by HIV virus, as well as delay progression to... Read more »

Will standrd HIV-2 Detect these?

Posted by Anonymous, 1 Reply

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15242544

AIDS Res Hum Retroviruses. 2004 Jun;20(6):666-72. Related Articles, Links

Identification of a highly divergent HIV type 2 and proposal... Read more »

Help me get through this...

Posted by Anonymous, 1 Reply

Hi- I have been checking this board some time now and think most of the information is very useful. That's why I'm coming out to ask a favor of you all. I was tested through STS in St. Louis a few months back (a year after my last exposure). The... Read more »

HIV?

Posted by Anonymous

Validation: Search for the Gold Standard

HIV tests should be validated against direct isolation of the virus from people that test positive, and lack of isolation in people who test negative.
Instead of just comparing people with AIDS against healthy... Read more »

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