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Hepatitis C Treatment Protease Inhibitors Trials

Here's a taste of what has to offer on this topic:
Get the Facts
AIDS InfoNet

Protease Inhibitors in Development

... Protease Inhibitors Protease Inhibitors in Development PIs No Longer in Development NOTE: Several fact sheets describe drugs that are being tested against HIV: Fact Sheet 410 : nucleoside analog reverse transcriptase inhibitors (nukes)
Ask the Experts

ANy new or trial treatments for Hepatitis c?

What are the newest drugs or treatments or trials for hepatitas C?Are there any websites that are useful ?Would a boil type knot be something typical for someone that has had hepatitias c for a number of years?Most DR's in a small cities do not...
Barbara McGovern, M.D.

Response from Barbara McGovern, M.D.

Tufts University School of Medicine
...There are several new treatments that are in trials right now for hepatitis C. The one which is very far along is a new protease inhibitor by Vertex Pharmaceuticals. There is also a protease inhibitor being studied by Schering Plough and Roche.... Read more »


Hello what treatment of hepatitis C (genotype 1) by (protease inhibitors) exist on the market? Are they all provided in hospitals? What is the cost of the treatment.Thank you very much
Brian Conway, M.D.

Response from Brian Conway, M.D.

University of British Columbia
There is a tremendous research effort underway to develop alteratives to combination therapy with interferon and ribavirin for HCV infection. This is especially true for genotype 1 infection, where the response rates are a bit lower. To date, the... Read more »

Protease Inhibitors with Hep C

I have failed my course of Interfuron therapy. Can you recomend studies going on I could become a part of with Protease inhibitors ??I live in South Florida
Barbara McGovern, M.D.

Response from Barbara McGovern, M.D.

Tufts University School of Medicine
I would go to the website "" to find a trial near you. Read more »


In taking hydroxyzine pam 25 mg,it states if you are on HIV Protease inhibitors, not to use. What is HIV Protease inhibitors?
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...HIV protease inhibitors are a family of HIV drugs (such as Kaletra, Viracept, Lexiva, Reyataz) used chronically for the treatment of HIV/AIDS. Read more »
HIV i-Base

Hepatitis C Treatment and Management

... Hepatitis C treatment: how, why, when Who needs treatment? How is hepatitis C treated? What is pegylated interferon? How long is hepatitis Read more »
U.S. Centers for Disease Control and Prevention

U.S., EU Grant Accelerated Reviews of Merck Hepatitis Drug

...trials in curing the infection compared to boceprevir, the two have not been tested head-to-head in the same study. Standard hepatitis C treatment involves a combination of pegylated interferon and ribavirin. It is hoped that protease... Read more »
Henry J. Kaiser Family Foundation

Phase II Clinical Trial Shows Vertex's Experimental Protease Inhibitor Lowers Hepatitis C Viral Loads to Undetectable Levels

...severe side effects and cure about 50% of the cases. According to the Times , Vertex is hoping VX-950 will reduce duration of treatment for hepatitis C patients to three months. However, despite "strong early results" from clinical trials, there... Read more »
The Body PRO

Double Protease Inhibitor Combinations

...had very good results on combinations which includedritonavir and saquinavir, and patients who had been previously treated withprotease inhibitors, in whom the results were generally disappointing. Abstract I-202. Safety and efficacy of a... Read more »
Connect With Others

Thanks for your support and any more advice?

Posted by motherinlaw, 3 Replies
I want to thank everyone for their support and help. I posted this in response to my own previous posting and felt it might have gotten lost in the shuffle and so am reposting. I have just spoken to my son again. He was finally able to convince... Read more »

bone density loss due to protease inhibitors

Posted by Anonymous, 1 Reply
Curious as to latest info. on research into bone density loss due to HAART therapy. Most research data i've seen goes back to 99 or 2000. Any new data/research into this? Also any info. on clinical trials currently under way looking into this... Read more »

lipodystrophy from protease inhibitors

Posted by Anonymous, 4 Replies
...good health. I have accessed all the major medications, plus vitamins to help fight the disease. Once I started taking the new protease inhibitors, I started growing breasts and huge amount of fat in the stomache area...infact, my entire torso... Read more »

Protease Inhibitors - Hemophilia bleeds

Posted by akcol
Hi, my fiance is a Long Term NonProgressor - 24 years positive, co-infection HCV, with severe Hemophilia A. This is a question for the gentlemen with Hemophilia please. We're requesting any input about any Hemophilic PI increased unusual bleed... Read more »