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Fusion Inhibitor Dosages

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AIDSinfo

An Overview of Fuzeon (Enfuvirtide, T-20)

... en-FYOO-vir-tide --> Brand Name: Fuzeon Other Name(s): DP 178, DP178, Enfuvirtida, Pentafuside, T 20, T-20, T20 Drug Class: Entry and Fusion Inhibitors Enfuvirtide, also known as Fuzeon or T-20, is a type of medicine called a fusion inhibitor. Fusion inhibitors work by blocking HIV from entering human cells. HIV/AIDS-Related Uses Enfuvirtide was approved by the
Ask the Experts

new drugs that block the ccr5 receptor?

Hi Dr. Bob, You are the most amazing expert on this site -not only sexy but by far- the most compassionate. i wish i could see you in person to squeeze you tightly and thank you. now, on to my question darling. My dearest doctor Bob -do you think...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
...antiretroviral (nucleoside reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitor, protease inhibitors or fusion inhibitor, specifically enfuvirtide) treatment-experienced adults with evidence of HIV-1 replication... Read more »

integrase inhibitors,where are they?

Dr. Frascino, I know we know of three crucial enzymes necessary for HIV to do its dirty work. Protease, reverse transcriptase and integrase. Why havent we created an integrase inhibitor. And where are we as far fusion inhibitors. Or any type of...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
...another "Plan B" type objection based on some looney-bird's misplaced morality!)I'll reprint some articles about integrase and fusion/entry inhibitors below. Some of it is rather technical. Sorry about that. But at least it shows they are indeed... Read more »

Salvage Therapy

Dear Dr.s,I've read on this forum that the new class of drugs, fusion inhibitors and/or integrase inhibitors being relaese this year, are recommended by you guys as "last resort". But with the clinical trilas showing great efficacy, why not use them...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
...questions.You've raised excellent points about how we go about deciding how to design an initial treatment regimen. Current issues about fusion and integrase inhibitors relate (in my mind) to the fact that the drugs are still in clinical... Read more »

when? when? when?

Dr. Dave,Ouch! T-1249 dead in clinical trials! And the next agent some time away in the pipeline, we all have to ask when seriously are we going to get new drugs? Any idea what part of the year?And what is up with the FDA trying to be all slick...
David Wohl, M.D.

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill
...Dear Jennifer, I agree. The T-1249 news is disappointing (Roche will halt clinical trials of T-1249 - a next generation of fusion inhibitor and instead concentrate on selling T-20) and anyone who is concerned/angry/frustrated/fighting mad should... Read more »
Articles
AIDS InfoNet

Enfuvirtide (Fuzeon)

...FuzeonĀ® or T-20, is a drug used for antiviral therapy. It is manufactured by Roche and Trimeris. Enfuvirtide is the first "fusion inhibitor" drug. When HIV infects a cell, it attaches to the outside of the cell. Then it "fuses" or joins itself... Read more »
AIDSinfo

An Overview of Selzentry (Maraviroc, Celsentri)

... mah-RAV-er-rock Brand Name: Selzentry Other Name(s): Celsentri, MVC, UK-427,857 Drug Class: Entry and Fusion Inhibitors Maraviroc, also known as Selzentry, is a type of medicine called an entry inhibitor. Entry inhibitors... Read more »
AIDS InfoNet

Taking Current Antiretroviral Drugs

...(Nukes) Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) (Non-Nukes) Part B: Combination Therapy, Protease and Fusion Inhibitors Combination Therapy Protease Inhibitors Fusion Inhibitors Part A: Nucleoside,... Read more »
AIDS InfoNet

Fusion and Attachment Inhibitors

... Attachment and Fusion Inhibitors Attachment and Fusion Inhibitors in Development Drugs No Longer in Development Note: Several fact sheets Read more »
Connect With Others

Excessive Mastubation

Posted by Anonymous, 5 Replies
Ever since I found out that I'm poz, I've been spending a lot more time mastubating. Is that normal? Or could it be because of the amount of time I've been spending reading posts about sexual issues? Pleasing myself has become an every day thing... Read more »

Integrase Inhibitor

Posted by Survivor
...all patient groups antiretroviral drugs, but one group received a placebo and the other groups received MK-0518 at different dosages over the 16 week study period. The antiretroviral drugs and MK-0518 combination reduced HIV viral loads to... Read more »

Fusion Inhibitor News?

Posted by Anonymous
...Does anyone know if the fusion inhibitor trials (phase III) are going OK, or where to go for an update? Last I heard 700 patients in 100 countries were in the Read more »

Late presenter......

Posted by Anonymous, 5 Replies
I have just recently been diagnosed with the following labs: CD4 count - 8 Viral load - 780,000 Potentially, I was infected over 10 years ago, but have been relatively symptom free. I was just wondering what percentage of others found themselves in... Read more »