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Facts About Indinavir

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AIDS InfoNet

Indinavir (Crixivan)

... What Is Indinavir? Who Should Take It? What About Drug Resistance? How Is It Taken? What Are the Side Effects? How Does It React With Other Drugs? What Is Indinavir? Indinavir is a drug used as part of antiretroviral therapy (ART).
Ask the Experts

switching from indinavir to Lopinavir/r

I have a patient has been well controlled with Indinavr+ AZT+3TC. But now Indinavir is not available. Will it be acceptable to use Lopinavir/r with same 2 NRTIs. The patient had previous exposure to Squinavir also.
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
Should not be a problem at all. Read more »

Indinavir sulfate

Dear Doctor,I have a question about the dose of Indinavir sulfate.According to a book about HIV/AIDs treatment (Published by POZ organization), the dose of Indinavir is 800mg three time a day and they also put a remark on the dose of this medicine...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
...Thanks for your post.Indinavir (Crixivan) can be dosed either way-- without ritonavir (Norvir) boosting, the medication is dosed every 8 hours, fasting. Indinavir Read more »

indinavir combivir lamivudine in pregnancy

Dear Dr,I would like to ask a very important question.A young collegue of mine registrar in Medicine had an accident with a needle that she used to do a Mantoux to an AIDS patient. She sterted immediately indinavir, combivir and lamivudine. She was...
Brooks Jackson, M.D.

Response from Brooks Jackson, M.D.

Johns Hopkins University, School of Medicine
...have become pregnant while on triple drug therapy, yet there have been very few,if any reports, directly linking Combivir or Indinavir with birth defects. BJ Read more »

Delavirdine interactions with Indinavir and other antiretrovirals.

Hi Dr. Cohen!Bob Frascino spoke to a group of us in Monterey, CA last week and began for the first time to explain why I have remained undetectable for so long(4+ years) on the same five drug regimen even though my dosing schedule was not precise. ...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
...does have similar effects on the p450 system as does ritonavir. Not as potent but similar. So yes you can dose reduce the IDV to 600 TID and do well. (not sure why you also have dose reduced the d4T and ddI but I'll leave that one for... Read more »
Articles
The Body PRO

Late Breaker No. LB16: Phase III, Multicenter, Randomized, Open-Label Study to Compare the Antiretroviral Activity and Tolerability of Efavirenz (EFV) + Indinavir (IDV), versus EFV + Zidovudine (ZDV) + Lamuvidine (3TC), versus IDV + ZDV + 3TC at 48 Weeks (Study DMP 266-006)

...counting the events on study. Those who reached PCR    OBS LOCF NC=F EFV/ZDV/3TC 98% 86% 71% EFV/IDV 83% 66% 53% IDV/ZDV/3TC 86% 61% 48% Statistically, there is a difference (p to suppress viral... Read more »
The Body PRO

Poster Session 22343: A Phase III, Double-Blind, Placebo-Controlled, Multi-Center Study to Determine the Effectiveness and Tolerability of the Combination of Efavirenz and Indinavir (IDV) versus Indinavir in HIV-1 Infected Patients Receiving Nucleoside Analogue (NRTI) Therapy at 24 Weeks

...8 weeks of experience with nucleoside reverse transcriptase inhibitor (NRTI) therapy compared the three drug combination of IDV plus 2 NRTIs (patient's choice) with the FOUR drug combination of efavirenz, plus IDV and two NRTIs. 180 patients had... Read more »
The Body PRO

Poster Session 12359: Durable Clinical Anti-HIV-1 Activity (72 Weeks) and Tolerability for Efavirenz (DMP 266) in Combination with Indinavir (IDV)

...results from which were first presented in San Francisco in September), patients received the protease inhibitor indinavir (IDV, 1000 mg every 8 hours) in combination with the experimental non-nucleoside reverse transcriptase inhibitor efavirenz... Read more »
The Body PRO

Effects of Switching from Saquinivir Hard Capsule (SQV-HC) to Saquinivir Soft Gel Capsules (SQV-SGC) or Indinavir (IDV)

...switching from saquinavirhard capsules (SQV-HC)(1.8 grams/d) to saquinavir soft gel capsules(SQV-SGC) (7.2 grams/d) or indinavir (IDV) (2.4 grams/d), or continuing theSQV-HC. Otherwise, the patients were maintained on their stable nucleosideRTI... Read more »
Connect With Others

PEP Question

Posted by agny, 1 Reply
...PEP. They didn't favor the idea becasue of all the side effects. Just a question about the prescription. They gave me three: Indinavir Sulfate: every 8 hours Nevirapine: Every 12 hours Abacavir Sulfate: Twice a day Wanted to make sure if there... Read more »

Lost

Posted by LostNconfused, 5 Replies
I tested positive 3 days before Christmas and I think I am still numb to the fact. I haven't told any friends or family because I really don't know how and most are judgemental and I'm sure will walk away. But I guess if they do, then I didn't need... Read more »

mas efectos del los trataminetos

Posted by Anonymous, 1 Reply
...Retrovir), d4T (estavudina, Zerit), 3TC (lamivudina, Epivir), abacavir (Ziagen), nevirapina (Viramune), efavirenz (Sustiva) e indinavir (Crixivan). Read more »

What do you think?

Posted by Anonymous, 2 Replies
...circulating in the blood] from HIV-seronegative healthy donors with increasing concentrations of IDV [indinavir], SQV [saquinavir], or ddI for 3 days and monitored T-cell proliferation and... Read more »