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Facts About Aptivus

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AIDS InfoNet

Tipranavir (Aptivus)

What Is Tipranavir? Who Should Take It? What About Drug Resistance? How Is It Taken? What Are the Side Effects? How Does It React With Other Drugs? What Is Tipranavir? Tipranavir is a drug used as part of antiretroviral therapy (ART). It is also called Aptivus. It is manufactured by Boehringer Ingelheim. Tipranavir is a protease inhibitor. These drugs prevent the protease enzyme from working. HIV protease acts like a chemical...
Ask the Experts

Lack of Ritonavir

Dear Doctors, I'm going to try to explain in english since dr Natterstad is not in service until sep-10. I live in Mexico and frecuently we have lack of medicaments. Since we do not have Ritonavir, since yesterday I'm taking 2 pills daily instead 4,...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Hello and thank you for your post from Mexico.Since tipranavir (Aptivus) requires ritonavir (Norvir)to achieve effective drug levels, it would be better to stop all of your antiretroviral medications until all of your medications are available.I... Read more »

aptivus side effects

Hi Iam curently on the combo.of500mg./aptivus2daily, didanasone400mg.1day, norvir200mg2day and 150mg.epivir1day. I have been pos.for23yrs.and am multi drug resistant.Thank the lord that this combination has been working for me for 2and a half years...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Sounds like you are having a good response to your regimen.Tiprinavir + ritonavir can increase blood levels of cholesterol and triglycerides but generally the levels haven't placed patients ( a small subset of patients have very serious increase in... Read more »

New One Pill a Day

I am currently on salvage therapy because of being resistant to almost all of the HIV. I am currently on Fuzeon a Aptivus, and truvada boosted with Norvir. My viral load initially went from 450,000 to 50,000 then down to 600 but then started...
Eric Daar, M.D.

Response from Eric Daar, M.D.

UCLA School of Medicine
Hi Loyd,Thank you for your posting. You raise several very important points.First of all, the new one pill per day is an important advance but unfortunately is not for everyone. In fact, it is primarily for those with very limited or no drug... Read more »

should I be worried about aptivus?

Hi,I just read on this site about a "black box" warning that Aptivus can cause "intracranial hemmorrage". What does this mean, and is this something I should be worried about?Thanks -- JD
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
The "black box" means that the FDA has issued a significant need-to-know about drug safety.In the case of tipranavir (Aptivus), a small, but significant number of patients developed intracranial hemmorrhage (ICH, bleeding in the brain) while... Read more »
Test Positive Aware Network


Common Name: tipranavir (TPV) Brand Name: Aptivus Class: HIV protease inhibitor (PI) Standard dose: Two 250 mg capsules with two 100 mg capsules of Norvir, both twice daily. Must be taken with Norvir. Oral solution available;... Read more »

An Overview of Aptivus (Tipranavir)

tip-RAN-na-veer --> Brand Name: Aptivus Other Name(s): TPV Drug Class: Protease Inhibitors Tipranavir, also known as TPV or Aptivus, is a type of medicine called a protease inhibitor (PI). PIs work by blocking protease, a... Read more »
AIDS InfoNet

Drug Names and Manufacturers

Reverse Transcriptase Inhibitors ("Nukes") Non-Nucleoside Reverse Transcriptase Inhibitors Protease Inhibitors Integrase Inhibitors Attachment and Fusion Inhibitors Antisense Drugs Immune Modulators None of these drugs can... Read more »
Test Positive Aware Network


Common Name: etravirine Brand Name: Intelence Class: non-nucleoside analogs (also called non-nucleoside reverse transcriptase inhibitors, NNRTIs or non-nukes) Standard dose: Two 100 mg tablets twice daily, with food. Take missed... Read more »
Connect With Others


Posted by LostNconfused, 5 Replies
I tested positive 3 days before Christmas and I think I am still numb to the fact. I haven't told any friends or family because I really don't know how and most are judgemental and I'm sure will walk away. But I guess if they do, then I didn't need... Read more »

Thanks for your support and any more advice?

Posted by motherinlaw, 3 Replies
I want to thank everyone for their support and help. I posted this in response to my own previous posting and felt it might have gotten lost in the shuffle and so am reposting. I have just spoken to my son again. He was finally able to convince... Read more »

testing info

Posted by Anonymous
Search Our Site Enter Keywords or Fact Sheet Number: Revised January 10, 2006 Hojas Informativas en Espaol: Newest Fact Sheets 128. Body Composition Tests 157. Microbicides 158. AIDS Myths and Misunderstandings 408.... Read more »

I am sooo sad today

Posted by Mix, 10 Replies
I knew that one day I would have to start the meds but I never thought it would be so soon. Went for my lab results today and my doctor dropped the bombshell. My CD4 count has dropped drastically (from 380 to 219 ) and i have to start my meds A.S.P.... Read more »