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Facts About Ziagen

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AIDS InfoNet

Abacavir (Ziagen)

...Abacavir? Who Should Take Abacavir? What About Drug Resistance? How Is Abacavir Taken? What Are the Side Effects? Hypersensitivity Reaction How Does Abacavir React With Other Drugs? What Is Abacavir? Abacavir (Ziagen) is a drug used as part of antiretroviral therapy (ART). It is manufactured by ViiV Healthcare. The FDA approved abacavir late in 1998. Several generic versions have been tentatively approved under PEPFAR (see ...
Ask the Experts

Doctor will not change Ziagen... My son is on it... 95% heart attach possibility?

Hello to my favorite Doctor Bob,This is Mommy of Three. I hope you are doing wonderfully. I am writing because once again I received from an email stating that there is now a 95% chance EVEN AFTER discontinuing Ziagen for risk of a...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
...Hi Mommy of Three,The relationship between abacavir (found in Ziagen, Epzicom and Trizivir) and the risk of heart attacks remains unclear. There have been studies indicating significantly increased Read more »

CNS penetration of Atripla/Ziagen/Isentress

AIDS patients need CNS penetrating anti-vral drugs, right Dr.? In order to bettter fight dementia, memory loss, etc., right? so, how do isentress, Ziagen and 3-in-1 Atripla stack up? Thanz!
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
...penetration of Isentress has not been well studied to my knowledge, but I would anticipate it would have excellent penetration. Ziagen has very good CNS penetration; efavirenz and emtricitabine have intermediate penetration; and tenofovir has... Read more »

switching from combivir to ziagen and epivir

Hi, I am a 35 year old male. I am currently on Reyataz and combivir. My viral load is undect. and tcells in the 600s. I have been on combivir for 2 and half years(use to take it with Kaletra) and the reyataz for about a year. I switched from Kaletra...
David Wohl, M.D.

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill
I think the switch should from Combivir to abacavir + 3TC (combined = Epzicom) is fine. Studies have shown that abacavir and another drug, tenofovir, are not associated with fat loss. In fact studies of people with fat loss while on d4T or AZT... Read more »


Dear Drl Holodniy:I have recently had a genotype worked and found that I am resistant to all HAART medications currently approved by the FDA. The only meds that they did not test for were Ziagen and Agenerase, the newly approved treatments for...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
...on the genotype. I can answer both of your questions together. Key mutations to AZT and 3TC, will make the virus resistant to Ziagen. In fact the more AZT mutations you have, with the critical one mutation for 3TC, the higher the resistance to... Read more »

An Overview of Ziagen (Abacavir)

... a-BAK-a-veer Brand Name: Ziagen Other Name(s): FABC, ABC sulfate, Abacavir sulfate, Sulfato de abacavir Drug Class: Nucleoside Reverse Transcriptase Inhibitors Read more »
Test Positive Aware Network


... Common Name: abacavir sulfate Brand Name: Ziagen Class: nucleoside analogs (also called nucleoside reverse transcriptase inhibitors, NRTIs or nukes) Read more »
Project Inform

Study Finds Heart Trouble With Ziagen and Videx

...A poster presented at CROI found a higher risk of heart attack ( myocardial infarction ) in people using the anti-HIV drugs Ziagen (abacavir, and in the fixed-dose combination pills Epzicom and Trizivir) and Videx (didanosine, Videx EC). ... Read more »
U.S. Food and Drug Administration

Ziagen 300 mg Scored Tablet Facilitates Pediatric Treatment of Infection With HIV

... On December 19, FDA approved Ziagen (abacavir) 300 mg scored tablets with corresponding dosing information for pediatric patients weighing 14 kg or more using the Read more »
Connect With Others

new drug...ziagen

Posted by Anonymous, 1 Reply
... Just watched the news and the FDA has just approved a new drug (Ziagen). They say the Ziagen is one pill taken twice a day and is usually taken with AZT. What a tremendous Read more »

swithching Ziagen to Viread...fatigue

Posted by Anonymous, 2 Replies
...Im 5 yrs in Ive been taking epivir,ziagen and viramune. Fatigue bacame an increasingly intolerable issue when I be gan Ziagen.(sorry, at yr. 3 I replaced d4tZerit with Read more »


Posted by Anonymous, 2 Replies the wrong forum, but the treatment forum isen't that active. I was told that they have developed a test for sensitivity to ziagen(for rechallenge purposes)and I can't find anything...Has anyone heard of this?? Read more »


Posted by Anonymous, 4 Replies
My doc just started me on Abacavir, to replace the Preveon I was taking, in combination with AZT and Viramune. I don't know much about Abacavir, except what I have found on Project Inform's site. I would like to hear... Read more »