Advertisement

The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter Download Our App
Professionals >> Visit The Body PROThe Body en Espanol

Facts About NNRTIs

Here's a taste of what TheBody.com has to offer on this topic:
Get the Facts
AIDS InfoNet

Non-Nucleoside Reverse Transcriptase Inhibitors in Development

Non-Nucleoside Reverse Transcriptase Inhibitors NNRTIs in Development NNRTIs No Longer in Development Note: Several fact sheets describe drugs that are being tested against HIV: Fact Sheet 410 : nucleoside analog reverse transcriptase inhibitors (nukes) Fact Sheet 440 : protease inhibitors Fact Sheet 460 : attachment and fusion inhibitors Fact Sheet 470 : new classes of antiretroviral drugs Fact Sheet 480 : immune therapies...
Ask the Experts

VL & CD4 COUNT

My VL count keeps on going up and down i.e between 900 and 300, whilst my CD4 count continues to increase every three months.What could b the problem? the VL only reach a level of 80 once and never undetactable, do you think i have a resistance? i...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
Based on your question and the fact that your CD4 count "continues to increase every three months", that you have been on your regimen for at least 6 months. If so, your viral load should have reached an undetectable level at this stage. The fact... Read more »

My Medicines

Hi EricI am from India 40 years old and I tested positive 3 months back and my cd4 was 109. The docs started me with Neverapine 200mg twice a day and Efferven 600mg daily night. After dew weeks I started developing rashes all over the body and face...
Eric Daar, M.D.

Response from Eric Daar, M.D.

UCLA School of Medicine
Thank you for your post.It is not surprising that you developed side effects with nevirapine and efavirenz. In fact, there was a study performed that compared two NRTIs with nevirapine, versus with efavirenz, versus with both NNRTIs together. The... Read more »

resistance time lines

Dr Daar,I know this is a wide opened question with no real fact based answers but is there a time line to when a resistance builds up to hiv even when your adherence is excellent?
Eric Daar, M.D.

Response from Eric Daar, M.D.

UCLA School of Medicine
Thank you for excellent question. Unfortunately there is no one answer. In general those initiating therapy that results in viral load declining to below the limits of detection will not experience viral rebound or develop drug resistance if they... Read more »

The Y181C Mutation

Dear Drs. Is the Y181C mutation that showed up 7 years ago after taken viramune that does not appear on a genotype done today rule out sustiva as a drug option? Thank you.
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for your post.In general resistance to one NNRTI [in your case, selected by nevirapine (Viramune) and evidenced by the Y181C mutation] confers resistance to other NNRTIs, like efavirenz (Sustiva). For this reason, if you've had previous... Read more »
Articles
AIDS InfoNet

Etravirine (Intelence)

What Is Etravirine? Who Should Take it? What About Drug Resistance? How Is it Taken? What Are the Side Effects? How Does it React With Other Drugs? What Is Etravirine? Etravirine is a drug used as part of antiretroviral therapy... Read more »
AIDS InfoNet

Protease Inhibitors in Development

Protease Inhibitors Protease Inhibitors in Development PIs No Longer in Development NOTE: Several fact sheets describe drugs that are being tested against HIV: Fact Sheet 410 : nucleoside analog reverse transcriptase inhibitors... Read more »
Test Positive Aware Network

Intelence

Common Name: etravirine Brand Name: Intelence Class: non-nucleoside analogs (also called non-nucleoside reverse transcriptase inhibitors, NNRTIs or non-nukes) Standard dose: Two 100 mg tablets twice daily, with food. Take missed... Read more »
AIDS InfoNet

Nucleoside Analog Reverse Transcriptase Inhibitors in Development

Nucleoside Analog Reverse Transcriptase Inhibitors Nucleoside Analogs (Nukes) in Development Nukes No Longer in Development NOTE: Several fact sheets describe drugs that are being tested against HIV: Fact Sheet 430 : non-nucleoside... Read more »
Connect With Others

Lost

Posted by LostNconfused, 5 Replies
I tested positive 3 days before Christmas and I think I am still numb to the fact. I haven't told any friends or family because I really don't know how and most are judgemental and I'm sure will walk away. But I guess if they do, then I didn't need... Read more »

One Year Ago

Posted by Blixer, 7 Replies
One year ago tonight (actually 52 weeks to the day) I made my first post in the "I Just Tested Positive" forum. I was a basket case. I had just been diagnosed hours before. I came here for help and I found it. I've grown a lot since then and I'm... Read more »

I'm trying not to scare anyone, but facts are fact

Posted by Anonymous, 6 Replies
In fact I'm not trying to scare anyone, and I don't want to make a kid's game out of the Bulletin Board. I'm just trying to make everyone realize that 99,9% of people doesn't cover all individuals, when talking about tests... I'm sure that 999 of... Read more »

info

Posted by Anonymous, 1 Reply
San Francisco AIDS Foundation Home Page California HIV/STD Referral Database About AIDSHotline.org Fact Sheet How to Volunteer Contact Us HIV/AIDS and STD Info Drug Resistant Strain of HIV - Q&A FAQ: HIV/AIDS FAQ: STDs ... Read more »