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Facts About Kaletra

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AIDS InfoNet

Lopinavir + Ritonavir (Kaletra)

What Is Lopinavir? Lopinavir is a drug used as part of antiretroviral therapy (ART). It is manufactured by Abbott Laboratories. Lopinavir is a protease inhibitor. The amount of lopinavir in the blood stream stays much higher if it is taken with a small amount of ritonavir, another protease inhibitor. See Fact Sheet 442 for more information on ritonavir. Kaletra® is a combination of lopinavir and ritonavir in the same tablet. In...
Ask the Experts

switching from Crixivan to Kaletra

Hi: I was on Crixivan and Combivir for over 4 years and responded very well with no negative side effects. My viral load broke through in the spring and tests show high level resistance to all those drugs. My doc has put me on Kaletra and Sustiva...
Susan Little, M.D.

Response from Susan Little, M.D.

University of California San Diego
In fact, Kaletra has the best profile of activity against virus with complete or partial resistance to other Protease inhibitors of all of the drugs in the PI class. I think that Kaletra is a very reasonable choice. Regarding the other drugs,... Read more »

How much fat to eat with Kaletra

I have been HIV + for 4 years, and just started meds two months ago with the Combivir and Kaletra. I was told to take the Kaletra with a "moderate fat meal." I understand this is so the drug is more completley absorbed. Can you tell me...
Brian Conway, M.D.

Response from Brian Conway, M.D.

University of British Columbia
Thanks for your comments on the site.It is true to say that food helps in the absorption of Kaletra. For example, the trough (lowest) drug concentration may be increased by about 30% if the medicine is taken with food.However, there is NO need for... Read more »

kaletra and lipo

Dr:I am 5 days into first treatment. Mr Dr. prescrived Kaletra, Viread and Emtriva. He said I will be on Kaletra just long enough to get my vl down (it is about 200K). I just heard that Kaletra has been linked to lipo? Is that true? What about...
Graeme Moyle, M.D.

Response from Graeme Moyle, M.D.

Chelsea and Westminster Hospital
Protease inhibitor drugs such as Kaletra are a higher risk for the development of lipoatrophy over time than NNRTIs drugs such as efavirenz. Protease inhibitor is may also be associated with a greater chance of gaining abdominal fat. The... Read more »

Late intake of Truvada and Kaletra

Doctor, I'm about to finish my second month of treatment (1 Truvada and 2 Kaletra at 8 am, 2 Kaletra at 8 pm). Had my CD4 cells and viral load tests 10 days ago and there was notorious improvement.I took my morning Truvada and Kaletra two hours...
David Wohl, M.D.

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill
Bravo on doing a great job taking your medications. A two hour delay in taking your medications will not harm you. I would say you have a window of time around each of your medication doses during which you can take the medications without any... Read more »
Connect With Others

Combivir & Kaletra

Posted by movingon
hello All

I am newly diagnosed , and it appears as if i have been infected for a few years without knowing because i have NEVER been sick. My doc reckons treatment should be started soon

I have heard good and bad stories about ALL HIV meds, and i am... Read more »

I'm trying not to scare anyone, but facts are fact

Posted by Anonymous, 6 Replies
In fact I'm not trying to scare anyone, and I don't want to make a kid's game out of the Bulletin Board. I'm just trying to make everyone realize that 99,9% of people doesn't cover all individuals, when talking about tests... I'm sure that 999 of... Read more »


Posted by Lovinlife, 3 Replies
Has anybody taken kaletra? I just started it. Am wondering what I can expect....... Read more »

Use of medication Kaletra

Posted by Anonymous, 1 Reply

Individuals currently taking the medication KALETRA are invited to participate in a "quality of life" study, consisting of a brief telephone discussion. Confidentiality is guaranteed. Compensation of $20.00 (U.S.). Please... Read more »