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Facts About Isentress

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AIDS InfoNet

Raltegravir (Isentress)

What Is Raltegravir? Who Should Take It? What About Drug Resistance? How Is Raltegravir Taken? What Are the Side Effects? How Does it React With Other Drugs? The Bottom Line What Is Raltegravir? Raltegravir (Isentress) is a drug used for antiviral therapy against HIV. It was formerly known as MK-0518. It is manufactured by Merck. Raltegravir is the first "integrase inhibitor" drug. When HIV infects a cell, it combines its...
Ask the Experts

Isentress & Truvada vs. Atripla

Due to a move, I'm now seeing a new HIV Specialist. I have been taking Adderall due to an inability to concentrate, foggy mornings, and fatigue. I've also been taking Atripla for the last 3 years, and it was my first HIV med that I've...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
Hello Oscar:Thank you for your questions. Your doctor is considering all the reasons possible for your "inability to concentrate, foggy mornings, and fatigue." Not all switches are for resistance to a drug. Sometimes switches are made due... Read more »

Isentress side effects

I started Isentress 30 days ago and I've been experiencing extreme itching in my lower extremities and rather annoying abdominal pain (it feels like a contusion inside of me). Will these diminish over time or just another fact of life with...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Raltegravir (Isentress)has been a generally well tolerated with fairly low rates of skin problems and abdominal problems. Usually raltegravir would be used with other HIV meds some of those may more commonly cause or contribute to skin or stomach... Read more »

Does reyataz isentress truvada first line therapy indicate pre-existing resistance?

Hi Dr. Young,I am undetectable on Atripla. My virus has no known resistance as confirmed before starting treatment. I recently had unprotected sex with another hiv positive gay man who is also undetectable on Reyataz/Isentress/Truvada as his first...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Hello and thanks for posting.I'm not one to judge irresponsibility; frankly positives have sex with positives all the time. Superinfection with drug resistance is surprisingly infrequent.It's pretty difficult to try to read a treatment... Read more »

Switching from Atripla to Truvada/Isentress

My question is of course, after the fact, so too late now. However, I made the decision to change from taking atripla to Truvada/Isentress with the discovery of horrific side effects I never connected to the atripla. I ordered the new meds, but...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Hello and thanks for your post.Sorry to hear of your side effects while on Atripla- likely due to the efavirenz component. Your comments highlight the need to first try to identify persons who might be at risk of such symptoms and to monitor after... Read more »
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isentress and truvada

Posted by anfan4, 2 Replies
im been on isentress and truvada for month and half and notice increased in blood pressure and any else had this problem. Will isentress cause this problem. Read more »

Isentress Drug - Side Effects?? HELP

Posted by design36, 1 Reply
I have been taking Isentress for about a month...Adnormal dreams, Insomnia, Excessive fatique have been side effects and seem to be ones for a lot of people. Does anyone have experience with this drug? Did the side effects get better? How long... Read more »

Isentress & Side Effects

Posted by design36, 3 Replies
I have been taking Isentress for about a month...Adnormal dreams, Insomnia, Excessive fatique have been side effects and seem to be ones for a lot of people. Does anyone have experience with this drug? Did the side effects get better? How long... Read more »

anyone taking Isentress and Invirase combination?

Posted by nevereasy
Isentress is a relatively new therapy. My Dr just added it to my mono therapy of Invirase (boosted with Norvir). I have been undetectable for two years on the Invirase but my Tcells never get over 300. He added Isentress. I have had bad reflux ( not... Read more »

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