Facts About Efavirenz

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Get the Facts

Efavirenz (Sustiva)

What Is Efavirenz? Efavirenz is a drug used as part of antiretroviral therapy (ART). It is also called Sustiva or Stocrin. It is manufactured by Bristol-Myers Squibb. Generic versions have been tentatively approved under PEPFAR (see Fact Sheet 475 ). Efavirenz is a non-nucleoside reverse transcriptase inhibitor (a "non-nuke" or NNRTI). These drugs stop HIV from multiplying by preventing the reverse transcriptase enzyme from working. This enzyme...

Ask the Experts

Starting treatment is 3tc/efavirenz/tonofovir a good bet?

I am asymtomatic HIV+ 33, positive for 2 years. My CD4/VL have been relatively stable although drifting down(for cd4). My last tests were dramatically different VL 700,000 (3months previously 50,000) CD4 203 (280). 18 (28). I am repeating the tests...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

I would agree with the assessment that starting medications in the near future would be a good idea-- you have a decreasing CD4 count and high HIV viral load.The treatment regimen of tenofovir (Viread)/ 3TC (lamivudine, Viread)/ efavirenz (Sustiva,... Read more »

emtricitabine, tenofovir, efavirenz first line offensive

I use the term "first line offensive" with strong conviction to anyone considering beginning treatment. I was diagnosed HIV positive in April of 2003 and suspect having been HIV positive for some time prior to that given the last time I...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Thanks for your thoughtful post.The combination of tenofovir (Viread)/ emtricitabine (Emtriva)/ efavirenz (Sustiva) is a newer low pill count option for first line treatment of HIV. While there aren't any formally presented studies on the... Read more »

saliva (Facts for Life: What you and the people you care about need to know about HIV/AIDS )

can i catch HIV if my partner "sprays" when he talks and his salive gets in my eye? Also can i get HIV from an infected partners saliva on my anus?...

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation

Hi,Saliva is not considered to be an HIV transmission risk unless it contains visible blood. See below.Dr. BobDr. Bob, very worried. Saliva came in touch with open wound,Nov 14, 2007 Dr. Bob, An escort was licking my face, later i realised that i... Read more »

efavirenz resistance

Hi DocLab tests just resulted in low level resistance to efavirenz. I am currently on truvada and efavirenz. My Doc wants to change to truvada and reyataz. I am concerned about the side effects of reyataz especially the yellowing of eyes and skin....

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital

Sorry to hear about the efavirenz (Sustiva) resistance.A switch to truvada + reyatazalone would not be a good move. You would also need to take a small (100 mg) dose of Norvir (ritonavir) to balance the regimen. Tenofovir, which is part of... Read more »

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Efavirenz: ways to fight its sleep-reduction.

Posted by BrokenWingedBird, 2 Replies

If Efavirenz (and Efavirenz along)is really wrecking your sleep quality, then the only solution is to stop taking Efavirenz (and substitute it with another drug).

However, there are ways to ensure your sleep is as good as possible.

Important discovery: Read more »

I'm trying not to scare anyone, but facts are fact

Posted by Anonymous, 6 Replies

In fact I'm not trying to scare anyone, and I don't want to make a kid's game out of the Bulletin Board. I'm just trying to make everyone realize that 99,9% of people doesn't cover all individuals, when talking about tests... I'm sure that 999 of... Read more »

ITS A FACT

Posted by Anonymous

Its a fact some of positive people lie about their status before sex. If you are going to have sex BE SAFE! dont believe people if they tell you they are negative, they may not be. ALWAYS PRACTICE SAFE SEX!!!!! I hope we learned something here.

Read more »

HIV FROM CONDOMS AFER FACT?

Posted by Anonymous, 2 Replies

What are the chances of catching hiv when:
You have sex with a male with the condom on, after he cums he pulls the condom off and you play around for around 10 minutes he puts his penis in you for a couple of seconds (about 2 inches)? Read more »

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