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Elisa 4th Generation Window Period

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Ask the Experts

4th generation ELISA test accuracy

Hi Dr Wohl,Thank you for the wonderful work you are doing!I am bit confused regarding the type of test to take and their respective window periods. It seems that the antibody test after 3 months has been the standard, but I have been reading that...
David Wohl, M.D.

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill
The p24 component of this test turns positive in about t a week after infection. Therefore, at 5 weeks a negative test is very reliable. DW... Read more »


Dear David,First of all, thank you for your time.I would like to know how good is a non-reactive... Read more »

4th generation testing

It seems the only way anybody gets a for certain "your negative" response anymore is if... Read more »
U.S. Food and Drug Administration

Fourth Generation HIV Diagnostic Test Approved, Permitting Earlier Detection of Infection

On June 18, 2010, FDA approved a new, "4th generation" HIV diagnostic assay. The ARCHITECT HIV Ag/Ab Combo Assay is the first HIV diagnostic assay that simultaneously detects both antigen and antibodies for the Human Immunodeficiency Virus (HIV).... Read more »

The 4th International Workshop on HIV Drug Resistance and Treatment Strategies

The Body Covers: The 4th International Workshop on HIV Drug Resistance and Treatment Strategies Sitges, Spain June 12-16, 2000 Conference Summaries Reports and Related Articles Cal Cohen, M.D. Resistance is one of the most crucial... Read more »
HIV i-Base

Third- vs. Fourth-Generation HIV Testing: Almost Half of UK Clinics Out of Step With National Guidelines

In 2011, prompted by calls to the i-Base phoneline reporting wide diversity in the information given to people contacting GUM clinics for HIV testing, i-Base wanted to understand why this was often different to UK guidelines. Although 4th generation... Read more »
AIDS Action Council

Protecting a New Generation from AIDS

The AIDS epidemic is quickly becoming a crisis of America's youth. Today, half of the 40,000 new HIV infections each year are among people under 25. The advent of new protease drugs in the mid-1990s ended the automatic death sentence previously... Read more »
Connect With Others

3rd or 4th generation elisas?

Posted by Anonymous, 1 Reply
I was wondering if any county health dept. around the country would be using elisas first generation. Is everyone using 3rd or 4th generation? Read more »

4th Generation HIV Test

Posted by Trophy

An arsenal of laboratory methods are available to screen blood, diagnose infection, and monitor disease progression in individuals infected by HIV. These tests can be classified into those that: (a) detect antibody, (b) identify antigen, (c) detect... Read more »

Eliza 4th generation

Posted by Anonymous, 1 Reply
The new Eliza 4th generation test tests for both antibodies and the virus itself. I don't know whether its already released to the general public. Anyway, a person testing negative for both after 30 days is considered hiv negative.No further tests... Read more »

Elisa 4 generation Window period in Spain

Posted by Anonymous, 1 Reply
I tell you what she has said to me the doctor here in Spain brings over of the Elisa 4 generation (is a test of antibodies vih-1, vih-2 of 3 generation combined with a test of the antigen p24 ), has said to me that it is very sure from the first... Read more »