Efavirenz Dose Forms

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Get the Facts

Efavirenz (Sustiva)

What Is Efavirenz? Efavirenz is a drug used as part of antiretroviral therapy (ART). It is also called Sustiva or Stocrin. It is manufactured by Bristol-Myers Squibb. Generic versions have been tentatively approved under PEPFAR (see Fact Sheet 475 ). Efavirenz is a non-nucleoside reverse transcriptase inhibitor (a "non-nuke" or NNRTI). These drugs stop HIV from multiplying by preventing the reverse transcriptase enzyme from working. This enzyme...

Ask the Experts

I miss my dose of Duovir and Efavirenz

I am taking usually the Duovir and Efavirenz twice a day and last night, I missed my dose and remember in the morning when my next dose is due (only duovir). What should I do? Should I take the efavirenz in the morning or just skip that missed dose?...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Missing a single dose of Duovir (AZT/3TC or Combivir in US) while taking efavirenz usually wont result in any problem such as quick development of drug resistance. Though you could take the dose of Duovir the next morning (thus two doses of Duovir... Read more »

Atripla+Extra dose of Efavirenz 200 mg

Hi Doc,I live in Australia and been diagnosed with HIV + active TB on January 2011.Now i still on TB medication ( Rifadin + Isoniazid) and for HIV i took Atripla once a day. My VL now 209 and CD4 Count 504.My doctor told me to have extra dose of...

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital

Dear Ivan,Your doctor is correct in adding the extra 200 mg of efavirenz while you are on TB treatment.This is because the rifadin (rifampin) will cause a DECREASE in the efavirenz level, which is compenated for by the extra 200 mg capsule.Once the... Read more »

whts the best form of treatmnet?

pls wht is the best treatment for a person esp if this person` used io magnetic tablets from helpcure.com before.?generally hats the best treatment now?...

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital

Thanks for the post. Treatment should be planned for each person, there is no cookbook. That is one size does not fit all. A test for drug resistance should be done first. Assuming that it shows no resistance in your virus to any medication, the... Read more »

Once daily dosing of etravirine (Intelence)?

I was on Efavirenz and Truvada but recently switched to Etravirine and Truvada because of sleep/dream/emotional issues. I saw some research that suggested the 400 mg dose of Efavirine could be taken safely once a day...

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital

There is a study with a new formualtion of Intelence that would be given once a day. We are waiting for final results and then the new form would have to get approval from the FDA. The current pills should not be taken once a day. Stay tuned.Joe... Read more »

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Low-Dose Naltrexone

Posted by renevatio, 1 Reply

Hello all-

I am newly diagnosed, and just getting into the process of researching all about HIV and potential alternative treatments. I am a voracious reader and spend a good bit of time each day reading papers and digging up info on my new internal... Read more »

Efavirenz: ways to fight its sleep-reduction.

Posted by BrokenWingedBird, 2 Replies

If Efavirenz (and Efavirenz along)is really wrecking your sleep quality, then the only solution is to stop taking Efavirenz (and substitute it with another drug).

However, there are ways to ensure your sleep is as good as possible.

Important discovery: Read more »

ritonavir in liquid form

Posted by Anonymous, 1 Reply

My partner just started taking ritonavir in the liquid form and it
tastes really bad. Furthermore, after taking it, he becomes very
nauseous and weak. We would like to hear from people with
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