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Drugs To Fight Lipodystrophy

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AIDS InfoNet

Body Shape Changes (Lipodystrophy)

No researcher has suggested that people with lipo should stop taking ART. What Causes Lipo? We do not know what causes lipo. There are different causes for fat loss and fat gain. Fat Loss Zidovudine (Retrovir, AZT) and stavudine (Zerit, d4T) are linked to fat loss. Efavirenz (Sustiva) may also contribute. Fat Gain One theory is that protease inhibitors interfere with the body's processing of fat. However, some patients who have never...
Ask the Experts

Using Steriods in fighting Lipodystrophy Cont.

Response:I would certainly consider changing your meds off of crix and D4T, the ones most responsible for this. You can afford to do this if your CD4 and VL are so good. I have no problem with steroids and they are helping for sure, but, using deca,...
Alvan Fisher, M.D.

Response from Alvan Fisher, M.D.

Brown University School of Medicine
yah but the effect you have seen is probably a dose effect...in other words the steroid effects are all additive.We know nothing scientifically about combined these drugs together in this manner.There are plenty of studies on steroid use in AIDS.... Read more »

Fighting Lipodystrophy

I was diagnosed with HIV in 2000. I have been taking Truvada combined with Kaletra for the past 3 years. I have noticed that my body is storing fat aggressively in my torso area and I am gaining mass in my breasts. I do not want to change meds.,...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Fat gain can be seen with a variety of HIV regimens-there is often no easy single approach to reverse or manage the problem. Fat gain is common in the general population so remains unclear how much is due to HIV infeciton itself or certain drugs or... Read more »

Using Steriods in fighting Lipodystrophy

Hello my name is Roland. currently I have been taking the following:Deca Durabolin staced 100mg to 600mg stacked, Oxandrin 2.5mg 5 pills a day and andrroal 50 at 50mg 3 times. a the start of my 9 week cycle I was showing signs of Lipodystrophy (...
Douglas T. Dieterich, M.D.

Response from Douglas T. Dieterich, M.D.

New York University, School of Medicine
I would certainly consider changing your meds off of crix and D4T, the ones most responsible for this. You can afford to do this if your CD4 and VL are so good. I have no problem with steroids and they are helping for sure, but, using deca, ox and... Read more »

Any studies on using steroids to fight Lipodystrophy

Are there any studies on using Steriods to fight Liphodystrophy. My doctr is uneasy about refilling my scripts without some proof that a "real" study(ies) is going somewhere she can talk to other doctors> HELP!!!...
Douglas T. Dieterich, M.D.

Response from Douglas T. Dieterich, M.D.

New York University, School of Medicine
I have found personally that anabolics like Decadurabolin and oxandrolone (Oxandrin) have been very helpful in battling lipodystrophy. We have done some preliminary studies and more are planned. Lipo is a very difficult topic and it will take a long... Read more »
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lipodystrophy from protease inhibitors

Posted by Anonymous, 4 Replies
I have known about my HIV+ status now for 6 years, and God has blessed me with continued good health. I have accessed all the major medications, plus vitamins to help fight the disease. Once I started taking the new protease inhibitors, I started... Read more »