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Disturbed Regulation Cd4 Cd8 Aids

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AIDS InfoNet

CD4 (T-Cell) Tests

What Are CD4 Cells? CD4 cells are a type of lymphocyte (white blood cell). They are an important part of the immune system. CD4 cells are sometimes called T-cells. There are two main types of CD4 cells. T-4 cells , also called CD4+, are "helper" cells. They lead the attack against infections. T-8 cells (CD8+) are "suppressor" cells that end the immune response. CD8 cells can also be "killer" cells that kill cancer cells and cells infected...
Ask the Experts

Negative, trush, inverted cd4/cd8

Dear experts,I am a Norwegian male 42 years old. Last September I performed oral sex on a girl who is definitely in the "low-risk"-category. I decided to forget the whole thing. However, 2-3 weeks after I developed red spots on my tongue...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hello Norwegian,Your T-cell subsets really aren't all that "strange." T-cells are involved in many illnesses other than HIV, and often can have transient, very normal variations up and down. Have you excluded HIV infection?... Read more »

CD4/CD8 results. Help

Hi doctor Bob,I am from Brazil, age 21. Back in the end of 2006, I performed unprotected cunnilingus in a sexworker. Since then, I am very disturbed by the risk of contracting HIV.In april 2008 I had a CD4 & CD8 test that resulted in CD4=869,...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hello.Now what's all this nonsense about being too scared to get an HIV test? If you're old enough to have sex, you're old enough to man-up and take responsibility for your actions. Besides, when it comes to HIV disease, knowing is... Read more »

My Lab resuts cd4/cd8 ratio =0.75 and absoulte cd4 count is 471

Hi doc,I have been tested HIV+ a week back my counts are cd4/cd8 ratio =0.75 and absoulte cd4 count is 471. so when should i start my treatment and how often should i test for cd4 in an year and do u think i should start ART now ? please advice...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
It is also important to know a couple of other numbers, what your CD4% is, and what your viral load results are. A normal CD4 count is between 500-1500 and a normal CD4% is between 30-50%. Your current CD4 count is just below the normal range. Many... Read more »

CD4 and CD4/CD8 ratio

Dear Cal, I have been recently diagnosed HIV+ (June 02) and have some questions regarding both the CD4/CD8 ratio and CD4 which do not seem to be spoken about as much as the CD4 absolute.My first question is what exactly are CD8 cells? What happens...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
Thanks Jim - glad this helps.So - about these cell counts. We simplify the immune system to make it easier to count and report things. And one important simplification is this one - we can distinguish two major types of important cells in the... Read more »
Connect With Others

Good News... PCR/CD4/CD8 results!!

Posted by uglyduck, 4 Replies
At, 18 days post exposure:

PCR = Undetectable (or as one of my HIV specialist said, NEGATIVE).
CD4: 476 (kind of low, but my HIV specialist says that is normal)
CD8: 494 (OK)
CD4/CD8 %: 27% (He says is OK).

Well, I just got my resutls and saw one of... Read more »


Posted by Anonymous, 3 Replies
Does anybody know what other viral infections apart from HIV can cause an inverted CD4:CD8 ratio?
Read more »

Negative but with a very low CD4 and CD4/CD8

Posted by tobeabetterman, 1 Reply
Hi everyone , sorry to bother again .
I was once told by dear kicker and riverprincess that my 3 months result is conclusive , thank you very much with my best wishes , and I'm sorry I have bother you again .
Some new situation make me nervous again .... Read more »