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Define Protease Inhibitors

Here's a taste of what TheBody.com has to offer on this topic:
Get the Facts
AIDS InfoNet

Protease Inhibitors in Development

... Protease Inhibitors Protease Inhibitors in Development PIs No Longer in Development NOTE: Several fact sheets describe drugs that are being tested against HIV: Fact Sheet 410 : nucleoside analog reverse transcriptase inhibitors (nukes)
Ask the Experts

Protease Inhibitors with Hep C

I have failed my course of Interfuron therapy. Can you recomend studies going on I could become a part of with Protease inhibitors ??I live in South Florida
Barbara McGovern, M.D.

Response from Barbara McGovern, M.D.

Tufts University School of Medicine
I would go to the website "Clinicaltrials.gov" to find a trial near you. Read more »

what is HIV PROTEASE INHIBITORS.

In taking hydroxyzine pam 25 mg,it states if you are on HIV Protease inhibitors, not to use. What is HIV Protease inhibitors?
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...HIV protease inhibitors are a family of HIV drugs (such as Kaletra, Viracept, Lexiva, Reyataz) used chronically for the treatment of HIV/AIDS. Read more »

Protease inhibitors

I like most HIV positive people are taking the protease inhibitor drugs. Is protease an enzyme? I ask this because I also drink wheatgrass juice on a daily basis and one of the enzymes it claims to boost is protease. What is the connection here?
Cade Fields-Gardner M.S., R.D.

Response from Cade Fields-Gardner M.S., R.D.

The Cutting Edge
...The job of protease inhibitors is to "inhibit" specific HIV protease enzymes. So, yes, proteases are enzymes, but protease inhibitors are not. There are enzymes Read more »

Resistance to protease inhibitors

If you have were infected years ago, before protease inhibitors came out, and you have not yet been on them, is it possible that because of loads of other treatments you are also resistent to them?And, if you have only taken Crixivan with treatment...
Susan Little, M.D.

Response from Susan Little, M.D.

University of California San Diego
...failed it you may have resistance to this drug. There is some degree of cross resistance between Crixivan and some of the other protease inhibitors (especially Ritonavir), so this may be an issue. Drug resistance testing will often help to sort... Read more »
Articles
U.S. Centers for Disease Control and Prevention

United Kingdom: "Virological and Immunological Outcomes at 3 Years After Starting Antiretroviral Therapy with Regimens Containing Non-Nucleoside Reverse Transcriptase Inhibitor, Protease Inhibitor, or Both in INITIO: Open-Label Randomized Trial"

...transcriptase inhibitors (didanosine + stavudine) plus either a non-nucleoside reverse transcriptase inhibitor (efavirenz, EFV) or a protease inhibitor (nelfinavir, NFV), or both (EFV/NFV) in HIV-1-infected patients who had not previously... Read more »
The Body PRO

Protease Inhibitors and Severe Adverse Events

...cohort (ANRS -- The French National Agency for AIDS Research). The study enrolled protease inhibitor-naive subjects who began protease inhibitors (PIs) between April 1997 and June 1998. Data was collected on December 31, 1999, with the follow-up... Read more »
U.S. Food and Drug Administration

Protease Inhibitors Backgrounder Table of Contents

...regimensfor these drugs may result in development of a resistantstrain(s) of HIV that will not be susceptible to treatment withprotease inhibitors. Patients must be aware of the need to takethe complete dose to lessen the risk of potential... Read more »
The Body PRO

Evaluation of Coronary Artery Calcification by Electron Beam Computed Tomography in HIV-Infected Men Receiving Prolonged Protease Inhibitor Therapy

...Parenti reported that there was a significant difference in coronary arterial calcification scores between patients on boosted protease inhibitors compared with single protease inhibitor use but yet there was no association between coronary... Read more »
Connect With Others

lipodystrophy from protease inhibitors

Posted by Anonymous, 4 Replies
...good health. I have accessed all the major medications, plus vitamins to help fight the disease. Once I started taking the new protease inhibitors, I started growing breasts and huge amount of fat in the stomache area...infact, my entire torso... Read more »

bone density loss due to protease inhibitors

Posted by Anonymous, 1 Reply
Curious as to latest info. on research into bone density loss due to HAART therapy. Most research data i've seen goes back to 99 or 2000. Any new data/research into this? Also any info. on clinical trials currently under way looking into this... Read more »

Hyperglycemia as a result of Protease Inhibitors

Posted by Anonymous
I found a product for reducing glucose levels. It is called Meishan Tea. They make 4 different kinds of tea and I have people that are showing tremendous results on all 4 kinds. However, the people that are presently taking the tea do not have... Read more »

Protease Inhibitors - Hemophilia bleeds

Posted by akcol
Hi, my fiance is a Long Term NonProgressor - 24 years positive, co-infection HCV, with severe Hemophilia A. This is a question for the gentlemen with Hemophilia please. We're requesting any input about any Hemophilic PI increased unusual bleed... Read more »