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Ddc In Hiv

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AIDS InfoNet

Zalcitabine (Hivid, ddC)

What Is ddC? ddC (HividĀ®) was a drug used for antiretroviral therapy (ART). It was manufactured by Roche. ddC was also known as zalcitabine or dideoxycytidine. ddC was a nucleoside analog reverse transcriptase inhibitor, or nuke. ddC was approved in 1992 as an antiretroviral drug (ARV) for people with HIV infection. The manufacture and distribution of ddC (Hivid) was discontinued by the manufacturer as of December 31, 2006.
Ask the Experts

Need to change from AZT and DDC

I'm HIV+ 22 years, asymptomatic, viral load never over 400 (last test 317), CD4 count 345 (has varied between 270 and 450, and was 310 when I tested positive in '86). I've taken old schools meds for 20 years, AZT and DDC. I can no...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
The first step would be to check a genotype to see if any viral mutations are present. But with a viral load so low it may not be possible to amplify enough virus to determine the genotypic mutations. If there is no genotypic data to help with the... Read more »

Resistences to azt & ddc

These were the only two resistences that came up in my test. And my question is which meds arent cross resistent to these two?. Can I take videx? Thank you...
Susan Little, M.D.

Response from Susan Little, M.D.

University of California San Diego
If you were told that you had resitance to azt and ddc, and do not have resistance to ddI (videx), then this might be a reasonable choice for you. In order to really recommend this, I would need to know your viral load and whether you had ever... Read more »

side effects of ddc - shortness of breath and dizziness

I have just begun treatment with kaletra, zerit and hivid. I seem to be tolerating the side effects from the kaletra and zerit very well but not the hivid. The particular concern I have is the dizziness, shortness of breath and perspiring that...
Brian Boyle, M.D., J.D.

Response from Brian Boyle, M.D., J.D.

Cornell University, Weill Medical College
It is possible that the symptoms you are mentioning are related to your antiretroviral therapy, but I doubt that it is the Hivid that is responsible. The dose of Hivid you are taking is lower than recommended, and I do not suggest that you decrease... Read more »

flu shot?

My friend has a count of about 325 and is on AZT and DDc-this Tuesday he is scheduled to have a flu shot at his clinic and I am concerned-I have heard that these shots can be dangerous--specifically that they can stimulate the replication of HIV...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
There have been some studies that suggest that the flu shot (and perhaps other immunizations) may lead to a brief rise in HIV viral load, which theoretically could accelerate the progression of HIV disease. On the other hand, there have also been a... Read more »
Connect With Others

DDC Bites the Dust

Posted by Bear60, 1 Reply
An HIV Drug Says Goodbye

by Tim Horn



July 27, 2006 (AIDSmeds)In a letter sent to doctors late last month, Roche Pharmaceuticals announced that it will be ending the sale and distribution of Hivid (zalcitabine, also known as ddC), a nucleoside reverse... Read more »

Ageing with AIDS

Posted by ScotCharles, 3 Replies
As many of you know, I was diagnosed with HIV in September 1984; but, as with many others, I probably was initially infected years earlier. I started AZT in 1994, then DDC, then epivir/zerit. I went off meds in 2000 at my insistence and didn't... Read more »

HIV medicines

Posted by Anonymous
Do you need ANY HIV related drug or any Opportunistic Infection medication, such as: Zerit (d4T), AZT, Abacavir, ddI, ddC, Crixivan, Fortovase, Saquanavir, Viracept, Virammune, Diflucan, any protease inhibitor available at the pharmacy? Do you need... Read more »

HIV is not for sissies

Posted by ScotCharles, 3 Replies
An editorial in my local paper bemoaned that the writer was saddened that his friend died of AIDS in 1994 just before the advent of drugs that would have allowed him to lead a long and healthy life. The editorial advocated that the readers should... Read more »