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DdI Dosages

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AIDS InfoNet

Didanosine (Videx, ddI)

Table of Contents What Is Didanosine? Who Should Take Didanosine? What About Drug Resistance? How Is Didanosine Taken? What Are the Side Effects? How Does Didanosine React With Other Drugs? What Is Didanosine? ddI (Videx) is a drug used as part of antiretroviral therapy (ART). It is manufactured by Bristol-Myers Squibb and by Barr Laboratories. Didanosine is also known as ddI or dideoxyinosine. Generic versions have been...
Ask the Experts

Overdose of DDI (Videx)?

I just discovered that I have been taking double the daily dosage of DDI (Videx) for over a month (4 of the 200mg tablets per day, instead of 2). I discovered this when I prepared to refill my RX (3-month mail order supply), only to find I had been...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
Well - if you have had no symptoms - you are probably OK. The biggest side effect of concern if this medication is taken at highest doses has been pancreatitis. Any inflammation of the pancreas is usually associated with symptoms of middle... Read more »

Nausea and Vomiting from DDI

I've been taking DDI (along with Viramune, Zerit and Hydrea) for the last two years. My viral load has remained undetectable with this combination. Recently I have been experiencing nausea and vomiting an hour following my dosage of DDI....
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
It would be somewhat unusual to just now start experiencing those symptoms due to the ddI. There have been some changes in the formulation which could alter how your body tolerates the drug. I often suggest trying the pediatric powder mixed 400 mg... Read more »

Resersatrol and ddI

I have one more question regading VIDEX EC. It appears that a red grape suppliment called Resveratrol may help to force HIV out of hiding. Please refer to http://www.cancer.gov/newscenter/pressreleases/HIVlatency . I wanted to try reservatrol,...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
Resveratrol is a very interesting compound that naturally occurs in red grape skins and has evidence supporting its use to extend lifespan in yeast cells and mice. This is the putative compound that is thought to account for health protective... Read more »

DDI and Eating Problems?

I have been on a combination therapy which includes DDI for approximately 4 months. I have experienced difficulty in swallowing and eating since beginning the regimen. I have lost close to 30 pounds in the last 4 months. I have heard that DDI can...
Douglas T. Dieterich, M.D.

Response from Douglas T. Dieterich, M.D.

New York University, School of Medicine
It's hard to answer with out more data, however DDI usually does not cause swallowing problems. It usually causes diarrhea. What do you mean it is working well? I assume that it is lowering the HIV viral load. Swallowing problems should be... Read more »
Connect With Others

taking ddi

Posted by Anonymous, 1 Reply
Taking ddi (Videx)? Do you drink alcohol? My Dr. says I should
have no alcohol as it increases the risk of getting pancreatitis.
I continue to have one beer or one gin and tonic after work and
figure I... Read more »

My partner was put on DDI

Posted by Anonymous, 1 Reply
Hi, My partner is HIV+ and has recently been put onto DDI and
AZT. I think, as a consequence, has become one of the most
unfriendly, annoying people in the world. Is this common, have
other people gone through this and come out the other side? I
need... Read more »

Sustiva or DDI/hydroxurea

Posted by Anonymous, 2 Replies
I am a female recovering addict and have been clean for over ten years. I am getting real weird side effects from Sustiva and even though I started taking it at night, I feel somewhat foggy during the day. Will this end and I feel somewhat normal... Read more »

Liver Function

Posted by NYRN, 1 Reply
I'm taking viread, invirase, didanosine, zidovudine and valtrex and my latest labs indicate high on the liver screens. Has anyone had any liver issues - I don't drink so it's not that! Read more »

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