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Damaged Immune System Late Seroconversion

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San Francisco AIDS Foundation

How HIV Damages the Immune System

Introduction The basic structure of HIV is similar to that of other viruses (Figure 1 ). HIV has a core of genetic material surrounded by a protective sheath, called a capsid . The genetic material in the core is RNA (ribonucleic acid), which contains the information that the virus needs in order to replicate (make more copies of itself) and perform other functions. You can think of RNA as the set of rules the virus follows in order to...
Ask the Experts

Immune System Damage

I have a question about immune system damage. I was diagnosed late (CD4 in the 60s and V/L off the charts) and remember talk about immune system damage. I was left with the impression that different parts of the immune system can sustain damage that...
Eric Daar, M.D.

Response from Eric Daar, M.D.

UCLA School of Medicine
Thank you for this excellent question. Unfortunately there remains many things we do not completely understand about the immune system and how it is affected by treatment. There certainly is evidence that not all parts of the immune system come... Read more »

Retraining a damaged immune system?

Is it possible to somehow re-train an immune system that has had "holes punched through it" by HIV?A long time ago, my ID doc explained that the damage HIV does to the immune system is somewhat like removing Z from the alphabet. You can...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
HIV infection causes both qualitative and quantitative damage to the immune system. Even with good viral suppression and decent immune recovery (as measured by CD4/T helper cell counts) the immune system does not return to normal. Factors... Read more »

reinfected with hiv damage immune system

I was wondering If I was Infected and reinfected a couple of weeks later. would that dammage the immune system so much that Iwould not be able to produce hiv antibodies. It's been 8 months and I've tested negative. Would a pcr dna test...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
Reinfection that close would not prohibit you from making antibodies. A PCR test now probably will not add anything.MH... Read more »

what is immune system damage?

Right or wrong, it has been my goal to delay treatment as long as possible. 10 years since infection and I'm still med free with good labs. However, I have seen the phrase "damage to the immune system" in reference to not starting...
Eric Daar, M.D.

Response from Eric Daar, M.D.

UCLA School of Medicine
Thank you for your post.The phrase you refer to is frequently used in very loose terms. The reason for this is that it really is not very specific or well defined. I suspect most use it to describe immunologic deficits that occur in people that... Read more »
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Stuff from web re. immune system a seroconversion

Posted by Anonymous, 1 Reply
I noticed that several people had been asking for information regarding the idea that an impaired immune system would explain seroconversion after 3 months or longer. Here is one post taken from Dr. Holodniy's site. I have seen several other... Read more »

So WHAT does cause late seroconversion??

Posted by Anonymous, 1 Reply
People are saying that it is definitely possible for someone to seroconvert later than the 4 or 6 week guideline.

So what causes this? What diseases? What conditions?? Read more »

recent news on late seroconversion: read last line

Posted by Anonymous, 4 Replies
http://www.thebody.com/confs/retro2006/wilkin1.html


Morpeth et al also described a single unusual case in which an individual did not develop an antibody response for one year after first having a viral load of more than 10 million copies/mL. This... Read more »

late seroconversion

Posted by Anonymous, 1 Reply
if you have ars 3 weeks after exposure then lasted a week
all the sign. then at sixth month you started having ,diarrhea
stomach pain and neuropathy tested at 22 weeks home acsess neg. can you have seroconversion symptoms
suchh as diarrhea... Read more »