Damaged Immune System Late Seroconversion

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How HIV Damages the Immune System

Introduction The basic structure of HIV is similar to that of other viruses (Figure 1 ). HIV has a core of genetic material surrounded by a protective sheath, called a capsid . The genetic material in the core is RNA (ribonucleic acid), which contains the information that the virus needs in order to replicate (make more copies of itself) and perform other functions. You can think of RNA as the set of rules the virus follows in order to...

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Immune System Damage

I have a question about immune system damage. I was diagnosed late (CD4 in the 60s and V/L off the charts) and remember talk about immune system damage. I was left with the impression that different parts of the immune system can sustain damage that...

Response from Eric Daar, M.D.

UCLA School of Medicine

Thank you for this excellent question. Unfortunately there remains many things we do not completely understand about the immune system and how it is affected by treatment. There certainly is evidence that not all parts of the immune system come... Read more »

obsesed with late seroconversion

Hi DoctorI have an obssesive doubt with seroconvertion.I had unprotected sex with a girlfriend without konwing her HIV status. 12 weeks after took ELISA was negative. 14 weeks after Took ELISA negative. I have always had an excellent inmune system I...

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation

Hello,You have "obssesive" doubt with "seroconvertion," because you are worried your "excellent 'inmume' system" would cause you to be a late seroconvertor???? Wow, that's a switch. Usually folks are... Read more »

Late Seroconversion and Virus in blood

Dr. Mark, I have done quite a bit of research on late seroconverters. It seems that the theory on these cases is that, rather than the virus being in the bloodstream for a long time; it is instead in an "eclipse phase" and bascially...

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine

I am still waiting to see those documented cases of late seroconversion. Your theory is only partially correct. Actually virus gets processed first within lymph nodes where it is recognized by the immune system as foreign and cytotoxic t cells... Read more »

Anemia and late seroconversion? (resubmitted form the Fatigue and Anemia Forum)

Dr. Bob: I tested HIV negative at 3 months via a rapid test that used my saliva. I also found out that I'm anemic (low MCV count) according to some recent blood work that was done. I would take the negative 3-month test as conclusive (esp....

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation

Hello,1.Would anemia and stress contribute to a late seroconversion? Nope!2.Are there specific factors that would cause someone to test negative until the six-month mark? Yes, immunosuppressive medications, for example.3.How accurate are oral fluid... Read more »

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Stuff from web re. immune system a seroconversion

Posted by Anonymous, 1 Reply

I noticed that several people had been asking for information regarding the idea that an impaired immune system would explain seroconversion after 3 months or longer. Here is one post taken from Dr. Holodniy's site. I have seen several other... Read more »

So WHAT does cause late seroconversion??

Posted by Anonymous, 1 Reply

People are saying that it is definitely possible for someone to seroconvert later than the 4 or 6 week guideline.

So what causes this? What diseases? What conditions?? Read more »

recent news on late seroconversion: read last line

Posted by Anonymous, 4 Replies

http://www.thebody.com/confs/retro2006/wilkin1.html

Morpeth et al also described a single unusual case in which an individual did not develop an antibody response for one year after first having a viral load of more than 10 million copies/mL. This... Read more »

late seroconversion

Posted by Anonymous, 1 Reply

if you have ars 3 weeks after exposure then lasted a week
all the sign. then at sixth month you started having ,diarrhea
stomach pain and neuropathy tested at 22 weeks home acsess neg. can you have seroconversion symptoms
suchh as diarrhea... Read more »

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