D4T Dosing

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An Overview of Zerit (Stavudine, d4T)

STAV-yoo-deen Brand Name: Zerit Other Name: d4T Drug Class: Nucleoside Reverse Transcriptase Inhibitors Approved Use: Treatment of HIV Infection WARNING: Stavudine can cause serious, life-threatening side effects. These include lactic acidosis (build up of acid in the blood), liver problems, and pancreatitis (inflammation of the pancreas). Contact your health care provider right away if you have any of the...

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D4T 30mg = less side effect?

my doctor has started me on a combination of d4t 30mg + 3tc 150mg twice daily effavirenz 600mg once at night. i am 74kgs when i asked him about a higher dose of d4t as my wgt is more than 60kgs .he assured me there will be no resistance to d4t if i...

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill

I am not aware of data that demonstrate that 40 mg and 30 mg of d4T (Zerit) are equal in their ability to suppress HIV (in people over 60 kg). That said, it may be possible. A recently reported study took patients who weighed over 60 kg and were... Read more »

Combining Lipitor and d4t/3tc?

I take the following throughout the day:7:30A Crix11:30A d4t/3tc3:30P Crix6:00P Lipitor11:30P Crix/d4t/3tcMy question is, can I combine my Lipitor with the 11:30A d4t/3tc dose?Thanks for your thoughts.S in Los Angeles...

Response from Cal Cohen, M.D., M.S.

Harvard Medical School

Many cholesterol lowering statins are supposed to be taken in the evening. The logic for this is that the enzyme they inhibit, HMGCoA, does most of its work at night synthesizing cholesterol. The manufacturer of lipitor does not push this as an... Read more »

Peripheral Neuropathy / D4T

I amtaking tenofovir, abacavir and D4T. I have neuropathy particularly on the left side (leg and lower arm/hand). I have expressed my concern with my doctor but he does not want me to stop taking D4T. On my own I have cut my dosage in half (1 in...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

It would be unusual for D4T related neuropathy to be localized like that so I would seek an alternative explanation. I would also be somewhat concerned about your regimen. There is some concern about use of tenofovir and abacavir together thought... Read more »

Lipidystrophy/D4T/Videx/Viracept

Dear Dr:I just started showing signs of lipidystrophy on one side of neck and one shoulder. I'm taking D4T/Viracept/Videx and for 5 years now. VL=1000 and TCell=550.I'm small Asian, but immune response has been great all these years. never...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

If possible switching off D4T/ddI to something like abacavir or tenofovir plus 3TC or FTC and switching off Viracept to Nevirapine or atazanavir (+ ritonavir) might help if those are options for you. Nutrition, exercise, and other interventions may... Read more »

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HALF DOSING MY MEDS

Posted by Anonymous, 1 Reply

Hello All !! I want to tell everyone that I started taking half of the prescribed doses of my meds about 2 years ago. My T cells remain High (570) and my V load is still undetectable..
I am on viramune,ziagen and zerit. I had an uncle who died... Read more »

dosing schedule adjustment

Posted by pozartistsd, 1 Reply

hey all you experts out there! I think i may know the answer to this but would like to get some input:

I currently take my meds (Reyataz/Truvada/Norvir) once a day. I take them at 9am (with breakfast, not that you need to know that

) I would like... Read more »

Skipping Doses

Posted by chrisnxs, 2 Replies

Hello Everyone, can someone please elaborate on the severity of skipping meds? My bf is positive and has been on meds for about a year. He's on my insurance and it kills the price down to a point where he can get his meds pretty easily. I discovered... Read more »

Low-Dose Naltrexone

Posted by renevatio, 1 Reply

Hello all-

I am newly diagnosed, and just getting into the process of researching all about HIV and potential alternative treatments. I am a voracious reader and spend a good bit of time each day reading papers and digging up info on my new internal... Read more »

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