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D4T Dose

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AIDSinfo

An Overview of Zerit (Stavudine, d4T)

... STAV-yoo-deen Brand Name: Zerit Other Name(s): BMY-27857, Estavudina, d4T Drug Class: Nucleoside Reverse Transcriptase Inhibitors Stavudine, also known as Zerit or d4T, is a type of medicine called a nucleoside reverse transcriptase inhibitor (NRTI). Stavudine works by disrupting one of the early steps in the HIV life cycle, called reverse transcription. During normal
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Can I take Zerit (Stavudine, d4T) with Viread (Tenofovir).

Hi, I just had a quick question. I've been researching everywhere but couldnt find an answer, if I'm taking Zerit (Stavudine, d4T) and Sustiva (Efavirenz, Stocrin), can I take Viread (Tenofovir).Thanks so much for all your help. God bless.
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
...Hello and thank you for your post.While d4T (Zerit) is not routinely used with tenofovir (Viread, Truvada),nor is this a commonly used NRTI backbone to be taken with efavirenz, Read more »

lower does d4t - side effects

sir,i started meds when my vl 264700 cd4 170 8.17% . i am on d4t 30mg+3tc+effavirenz.even though my weigth was 85 kgs my doc started me on a lower dose of d4t . this was the most prefered combination 50 wks back in india.today my vl <20 cd4 510...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...preference to to switch pro-actively before fat is lost so if tenofovir or abacavir were available and affordable I might switch from D4T to one of those agents. KH Read more »

D4T 30mg = less side effect?

my doctor has started me on a combination of d4t 30mg + 3tc 150mg twice daily effavirenz 600mg once at night. i am 74kgs when i asked him about a higher dose of d4t as my wgt is more than 60kgs .he assured me there will be no resistance to d4t if i...
David Wohl, M.D.

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill
...I am not aware of data that demonstrate that 40 mg and 30 mg of d4T (Zerit) are equal in their ability to suppress HIV (in people over 60 kg). That said, it may be possible. A recently reported Read more »

Peripheral Neuropathy / D4T

I amtaking tenofovir, abacavir and D4T. I have neuropathy particularly on the left side (leg and lower arm/hand). I have expressed my concern with my doctor but he does not want me to stop taking D4T. On my own I have cut my dosage in half (1 in...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...It would be unusual for D4T related neuropathy to be localized like that so I would seek an alternative explanation. I would also be somewhat concerned Read more »
Articles
The Body PRO

ddI + d4T Combination Therapy Proves Effective

...National Conference on Retroviruses and Opportunistic infections confirmed the benefit of combination therapy with ddI and d4T. One group from Nice led by Durant treated 25 patients with mean entry CD4 counts of 116 cells/mm3 and plasma RNA... Read more »
The Body PRO

Abstract No. 420: A Phase I Study of Hydroxyurea in HIV-Infected Children Receiving Didanosine (ddI) and/or Stavudine (d4T)

...Medicine, evaluated the safety, antiviral and immunologic effects, and pharmacokinetics of hydroxyurea, given with ddI and/or d4T to symptomatic HIV-infected children. It is among the first to look at the use of HU in children. The children... Read more »
The Body PRO

Session 84, Abstract 664: Therapy with d4T plus 3TC Produces Sustained Undetectable Levels of Plasma HIV RNA in Patients Treated with Reverse Transcriptase (RT) Inhibitors for 10 Years

...time they sequentially received AZT monotherapy (mean duration of 83 months), AZT + ddI (mean period of 12 months), high-dose d4T "pulse therapy" (for a mean duration of 48 weeks), and, most recently, d4T plus 3TC. Prior to receipt of d4T plus... Read more »
The Body PRO

Abstract No. 398: Treatment with d4T + ddI + Nelfinavir + Hydroxyurea for Early or Recent Primary HIV Infection

...Researchers from UCSF presented data from a study designed to assess the efficacy of a four-drug combination -- ddI/d4T/nelfinavir/hydroxyurea -- for patients with "early" HIV infection (defined as asymptomatic patients with a T-cell, or CD4,... Read more »
Connect With Others

Bristol Myers Squibbs: Videx

Posted by Anonymous, 2 Replies
Gentlemen, Stay away from Videx it infected my pancreas and made me diabetic, apprantly it does that to a high percentage of people on it or as I also understand kills another hign percentage of them. What does Bristol Myers Squibbs do? Sell death... Read more »

Positive denial

Posted by Anonymous, 7 Replies
I've been positive since 1992 and have been in denial since then. I chose to "ignore" my result until 2004 and just put it at the back of my mind. I finally decided to go to a doctor - not because I was sick, but to get my viral load taken. I've... Read more »

What should I think?

Posted by motherinlaw, 9 Replies
I will try not to make this too long...my son called yesterday and told me his wife was not doing well. My HIV negative son and three HIV negative grandchildren may soon lose their HIV positive wife and mother. My son and daughter-in-law seem not to... Read more »

about to start treatment

Posted by Anonymous, 4 Replies
hi. kinda scared.. about to start treatment. My dr wants to use an induction/maintenance strategy starting with an intense four-drug Kaletra (LPV/r, lopinavir/ritonavir)-based regimen along with Combivir [AZT/3TC] + Viread [tenofovir]. can you tell... Read more »