The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter Download Our App
Professionals >> Visit The Body PROThe Body en Espanol

Cushing's Syndrome And Buffalo Hump

Here's a taste of what has to offer on this topic:
Ask the Experts

buffalo hump

I know the buffalo hump will develop in cases in extreme conditions of the adrenal glands--Cushing's syndrome. Why does it develop in HIV/AIDS? Is it the side effect of medicine, or does the medicine effect the adrenal glands/cortisone which then...
Brian Conway, M.D.

Response from Brian Conway, M.D.

University of British Columbia
In a limited number of patients, it may well be some abnormally increased cortisol level. However, in HIV infection (and particularly with its treatment with certain drugs, such as the older protease inhibitors), there is some abnormality of how fat... Read more »

buffalo hump growing while off drugs?

Drs,This has really been driving me crazy. I stopped all HIV drugs 1 1/2 yrs ago after taking... Read more »
PWA Health Group


...believe that RU486 may be useful in treating lipodystrophy because of the similarity between this condition and a disorder called "Cushing's syndrome." In fact, patients with lipodystrophy were often believed to have Cushing's syndrome at first... Read more »
Women Alive

The New Body of AIDS

...causing the metabolic changes. These symptoms are very similar to the ones caused by an increase of Cortisol levels, known as Cushing's Syndrome. None of the patients tested for Cortisol, however, has presented abnormal levels Clinicians are... Read more »
Body Positive

HAART to Heart

...hump done in California in 1998. The investigators wanted to see if people with HIV and AIDS who had buffalo hump also had Cushing's Syndrome, a condition that results from the overproduction of hormones from the adrenal glands located on the... Read more »
Gay Men's Health Crisis

Protease Inhibitor Side Effects Take People by Surprise

...patientsdeveloped the condition shortly after initiatingtriple combination therapy with protease inhibitors,indinavir in particular. Cushing's syndrome, a condition with similar physicalmanifestations, has been ruled out for the time... Read more »
Connect With Others

buffalo hump

Posted by Anonymous, 5 Replies
...has anyone experienced a "buffalo hump"? my doctor says that not enough information is known about the cause or treatment of it. i have consulted with a plastic surgeon Read more »

Buffalo Hump Just Starting

Posted by mike55, 6 Replies
Hi, I have been successly treated with Trizivir for four years (since becoming HIV+). All was well until a few weeks ago I noticed the dreaded hump starting to appear behind my neck. I would like to hear experiences from anyone going through this... Read more »

More info

Posted by yoshimi2, 1 Reply
...event took place on 2 November 09, and I know because he used to be thin, now he has lypodystrophy, nine month pregnant belly, buffalo hump on back, plus he used to be an idu. Lets say I am 99.9 sure his is pos. Also he is avoiding my... Read more »

2 years later

Posted by Anonymous, 4 Replies
After a 2 yr. neg. elisa my symptoms still have me worried. Besides all the other symptoms that I convinced myself were from stress, this last symptom has me worried. My breast have gotten huge along with my stomach. Sometimes I think and know I... Read more »