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Contraindications To Zidovudine Therapy

Here's a taste of what has to offer on this topic:
Get the Facts
AIDS InfoNet

Zidovudine (Retrovir, AZT)

...Zidovudine? What About Drug Resistance? How Is Zidovudine Taken? What Are the Side Effects? How Does Zidovudine React With Other Drugs? What Is Zidovudine? Zidovudine (Retrovir) is a drug used for antiretroviral therapy (ART). It was first manufactured by GlaxoSmithKline. It is manufactured by ViiV Healthcare. The patent on zidovudine expired in 2005 and several generic versions have been approved. Several are available under...
Ask the Experts

Want to stop taking my PEP

Hi Dr.Bobabout 1 week ago i bottomed for this guy that i was drinking with one night. I made him put a condom on before we started because i never ever have unprotected sex. However, he ripped it off during sex without me knowing. when i realized...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
...testing. There are a number of medical interventions that might help your symptoms. If there are contraindications to using these therapies or if your symptoms persist or worsen, a complete change of your PEP regimen may be warranted. (Zidovudine... Read more »


I am working in treatment advocacy with HIV patients. Recently one of my patients stated that she was told by a kidney specialist that 300 mg of Zidovudine is to strong for her liver. she is having difficulty having the recommended dose of 100 mg...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...It is somewhat unusual for standard doses of zidovudine to be too strong for the liver . If she is seeing a kidney specialist and has some degree of kidney failure then the dose of Read more »

zidovudine, didanosine, kaletra

Is the above combination suitable for one considered to be resistant to combivir and effavirenz? I have come across these in the internet. My doctor thinks I could be resistant to combivir and effavirenz. I have been on them for 2 years. Due to...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
...Hello,Ideally speaking, if resistance develops to a HAART (highly active antiretroviral therapy) regimen, I recommend getting a resistance test to help guide the choice of the next regimen. If resistance testing is not an Read more »

want to know my meds side effect

hello, before 2month I started one of the available ART regimens in my country lamivudine150mg+zidovudine300mg and nevirapine300mg bid my CD4 was 194&no AIDS related question is what are the main side effects of this combinations&one day...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
...side effects may be more likely to occur from the zidovudine including loss of fat in the limbs and cheeks. Unfortunately mono-therapy is not likely on the horizon since the HIV virus has great ability to develop resistance to any single, or... Read more »
The Body PRO

Stavudine, Zidovudine and Protease Inhibitor Therapy Effects on Subcutaneous Leg Fat Wasting in HIV-Infected Males

... Effect of Stavudine, Zidovudine and HIV Protease Inhibitor Therapy on Subcutaneous Leg Fat Wasting in HIV-Infected Males -- A Longitudinal Study (Abstract 28) Presented by David Nolan Two Read more »
The Body PRO

Maternal Viral Genotypic Zidovudine (ZDV) Resistance and Infrequent Failure of ZDV Therapy to Prevent Perinatal Transmission

...Dr. Robert Coombs of the University of Washington presented data fromthe ACTG 076 study of the use of antiretroviral therapy in preventing HIVtransmission which suggested that AZT resistance was not associated with HIVtransmission. In this study,... Read more »
The Body PRO

I-57: Treatment of Primary HIV Infection with Zidovudine, Lamivudine and Indinavir: A Case-Control Study

...More data is accumulating that initiation of combination antiretroviral therapy may have a greater impact on preservation of immune function when used earlier in the course of disease, and CDC guidelines for Read more »
The Body PRO

Poster Session 12311: Indinavir in Combination with Zidovudine (ZDV) and Lamuvidine (3TC) in Treatment-Naïve Patients with >500 CD4 Cells/mm 3

...was defined in the study as HIV levels greater than 1,000 copies/mL, CD4 cell counts of at least 500 cells/mm 3 , no previous treatment with an antiretroviral and no history of HIV-associated conditions. Mean baseline viral load was a relatively... Read more »
Connect With Others

Thanks for your support and any more advice?

Posted by motherinlaw, 3 Replies
I want to thank everyone for their support and help. I posted this in response to my own previous posting and felt it might have gotten lost in the shuffle and so am reposting. I have just spoken to my son again. He was finally able to convince... Read more »

want to have a baby, but worried

Posted by kolo, 1 Reply
...?troubling? but emphasised: ?There is a need for careful monitoring of the future health of children who received AZT-based therapies [in the womb], the development of new safer NRTIs and the identification of drugs that will mitigate the side... Read more »


Posted by Anonymous
...diagnosis permits patient education as well as treatment that may delay disease progression. Triple-combination antiretroviral therapy should be started immediately and continued indefinitely. Compliance with medication regimens is essential to... Read more »

What should I think?

Posted by motherinlaw, 9 Replies
I will try not to make this too son called yesterday and told me his wife was not doing well. My HIV negative son and three HIV negative grandchildren may soon lose their HIV positive wife and mother. My son and daughter-in-law seem not to... Read more »