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Complete Protease Inhibitor Cocktail Tablets

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Aptivus

Brand name: Aptivus Generic name: tipranavir, or TPV Class: Protease inhibitor (PI) Manufacturer: Boehringer Ingelheim, www.aptivus.com , (800) 542-6257 AWP: $1,420.09/month; $419.84 for 95 mL bottle of solution Standard Dose: Two 250 mg capsules with two 100 mg capsules of Norvir, both twice daily. Must be taken with Norvir. Oral solution available; both formulations available for children ages 2 years and older. Must take with...
Ask the Experts

Hypogonadism from protease inhibitors

I am a 33-yr-old male who was diagnosed two years ago during my seroconversion illness, and immediately began triple cocktail therapy with Crix/AZT/3TC, and have remained undetectable since that first diagnostic viral load test. After 13 months of...
J. B. Molaghan, N.P., A.C.R.N.

Response from J. B. Molaghan, N.P., A.C.R.N.

San Francisco General Hospital
HelloThanks for such a nicely detailed clinical summary. Although we assume that hypogonadism is only associated with HIV disease progression, we don't really know if it occurred in early HIV disease, because we never looked for it. In fact,... Read more »

Protease Cocktail: A Road to Lipodystrophy?

In a recent response to a recent question I posed regarding my overt failure to gain weight after 12 weeks' of Sersotim, you said that I would have benefited more from Serostim had I removed the agents of Kaletra, Crixivan, and Viread from my...
Brian Conway, M.D.

Response from Brian Conway, M.D.

University of British Columbia
Crixivan is clearly associated with lipoatrophy, but more often with fat accumulation. The same can be said of Kaletra, although to a somewhat lesser extent. Viread is not associated with any of these complications. Of the protease inhibitors,... Read more »

protease inhibitors

Dear Mr. Sowadsky; Please describe Protease Inhibitors, how they work, and their role in drug cocktail therapy....
Rick Sowadsky, M.P.H.

Response from Rick Sowadsky, M.P.H.

Nevada State Health Division AIDS Program
Hi.Thank you for your question.Your question addresses so many issues that it's too long to answer in thisforum. However, a good written source for your questions is in a bookletentitled, "Protease Inhibitors: A New Family of Drugs for... Read more »

Going off Protease Inhibitors

I am in a situation, like many, where the protease inhibitors are not really working for me very well any more. My T cells are at 300 and my viral load is at 29,000. I am a long term survivor (ten years) who was diagnosed with AIDS as a result of...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for your question.It certainly sounds like you have evidence of viral resistance to your current treatments. An important decision at this point is whether to continue on therapy (with a treatment switch) or to discontinue therapy.I probably... Read more »
Connect With Others

Hyperglycemia as a result of Protease Inhibitors

Posted by Anonymous
I found a product for reducing glucose levels. It is called Meishan Tea. They make 4 different kinds of tea and I have people that are showing tremendous results on all 4 kinds. However, the people that are presently taking the tea do not have AIDS.... Read more »

lipodystrophy from protease inhibitors

Posted by Anonymous, 4 Replies
I have known about my HIV+ status now for 6 years, and God has blessed me with continued good health. I have accessed all the major medications, plus vitamins to help fight the disease. Once I started taking the new protease inhibitors, I started... Read more »

bone density loss due to protease inhibitors

Posted by Anonymous, 1 Reply
Curious as to latest info. on research into bone density loss due to HAART therapy. Most research data i've seen goes back to 99 or 2000. Any new data/research into this? Also any info. on clinical trials currently under way looking into this... Read more »

Protease Inhibitors - Hemophilia bleeds

Posted by akcol
Hi, my fiance is a Long Term NonProgressor - 24 years positive, co-infection HCV, with severe Hemophilia A.

This is a question for the gentlemen with Hemophilia please.
We're requesting any input about any Hemophilic PI increased unusual bleed... Read more »