Combivir Facts

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Combivir (Zidovudine + Lamivudine)

What Is Combivir? Combivir is a pill that contains two drugs used as part of antiretroviral therapy (ART): zidovudine (Retrovir, AZT) and lamivudine (Epivir, 3TC). Combivir is manufactured by ViiV Healthcare. Generic versions have been tentatively approved under PEPFAR (see Fact Sheet 475 ). Lamivudine is also known as 3TC. The drugs in Combivir are called nucleoside analog reverse transcriptase inhibitors, or nukes. These drugs block the...

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Combivir and Viramune Combination - Time for a Switch?

Dear Dr:I have been positive since February 2003. My CD4 is 708 and my viral load has been undetectable since December 2003. I have been taking Combivir and Viramune since April 2003 with no problems except some fatigue. I am concerned about facial...

Response from Eric Daar, M.D.

UCLA School of Medicine

Thank you for your post.It sounds like you have done fantastic on therapy with excellent viral suppression and high CD4 cells. To answer your question I would need to know whether you are developing facial lipoatrophy and/or neuropathy or are simply... Read more »

Crixivan/Norvir vs. Viramune/Combivir on a budget

I was recently diagnosed HIV+. VL around 35,000 CD4+ 350. I am thinking about treatment. My doctor wants me to start on Crixivan, Norvir, Videx EC, & Zerit. Here in Thailand, this will cost over 400 a month. Another option is locally made...

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine

Given that viral load and the fact you are drug naive, viramune and combivir should be effective in achieving an undetectable viral load.MH... Read more »

Switching from Combivir & Sustiva to Atripla

I have been HIV positive since June of 2001. My CD4 count has always been over 739. When my viral load consistently climbed over a period of a year, my doctor recommended treatment. At the time, my viral load was at just under 20,000. He advised...

Response from Eric Daar, M.D.

UCLA School of Medicine

In general I believe that if someone is on a good regimen that is working and well tolerated there is little reason to change. The one reason in this case to consider a modification of your therapy is the development of potential toxicity.... Read more »

Sutiva/Combivir and stomach problems

Ive been on Sustiva and Combivir now for a year. Firstly, the weird dreams from Sustiva havent stopped, though Im used to them now - and in fact, I often wonder as I go to bed, what I will dream about tonight, and Im sure that if I could remember...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Pancreatitis due to your current regimen is not very common. If you changed meds I would not be sure that the next regimen would be any better/safer. AZT can cause lingering GI complaints in some patients so a switch to abacavir or tenofovir might... Read more »

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Combivir & Kaletra

Posted by movingon

hello All

I am newly diagnosed , and it appears as if i have been infected for a few years without knowing because i have NEVER been sick. My doc reckons treatment should be started soon

I have heard good and bad stories about ALL HIV meds, and i am... Read more »

Viread,Combivir,Keletra:Med. Schedule that ROCKS!!

Posted by Anonymous

My friends,
I discovered a medicine regimen...that included the medicines above...and took a 7k viral load to >50 in a month and a half...as my nurse practitioner is convident in my addhearance to my meds...she allows me to find the most tolerant... Read more »

I'm trying not to scare anyone, but facts are fact

Posted by Anonymous, 6 Replies

In fact I'm not trying to scare anyone, and I don't want to make a kid's game out of the Bulletin Board. I'm just trying to make everyone realize that 99,9% of people doesn't cover all individuals, when talking about tests... I'm sure that 999 of... Read more »

Combivir only for PEP?

Posted by scaredofhiv, 1 Reply

Hi,

I was prescribed Combivir for a PEP regimen as a precaution following a possible exposure. From what I can gather on the web, Combivir is typically prescribed in tandem with another drug. Was the doctor unwise to prescribe the Combivir only?... Read more »

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