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Cell Markers Expressed By Cd4 T Cells

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AIDS InfoNet

Immune Therapies in Development

...Advanced Biotherapy is studying a TNF-alpha blocker in a Phase I trial. TXA127 (angiotensin 1-7) stimulates bone marrow to produce progenitor cells. These can develop into several types of immune cells, including CD4 T cells. Therapeutic Vaccines Therapeutic vaccines improve HIV-specific T-cell responses in patients whose viral load is suppressed by ART. This should permit better control of HIV if the ART is stopped. Another...
Ask the Experts

off meds for 4 years , still undetecable w/ 1300 t cells

unfortunatly my specialist is retieng and without giving false hope suggested that if I remained undetectale for 2 more years it is possible i may have cleared the virus.I did begin meds within 8 weeks of exposure and was 99.9% compliant for 3.5...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
...of tactics to suppress HIV.Pursuing the Keys to HIV Control Dr. Connors' group focuses on immune-system cells known as CD8+ T cells, also called "killer" T cells. As their name implies, killer T cells hunt down infected cells and destroy them.... Read more »

cd4 and t-cells

hiim 30 years old and im hiv+ and hep c+. i just would like someone to explain in simple words, how to understand what is and how i read my cd4 count and all that stuff. i just wanted a symple explanation if its possible.i hope u understand my...
Barbara McGovern, M.D.

Response from Barbara McGovern, M.D.

Tufts University School of Medicine
...When you have HIV infection, you want your virus to be at low levels and your T cells to be high. The T cells we concentrate on are the CD4+ T cells which protect you against infection. Hepatitis C can cause liver Read more »

CD3/CD4 what it means?

Dear Dr.Holodniy,Thank you for your endless work on this forum.I have found it very educative and helpful.Please could you explain what it means:CD4/CD3 45/62 (44)*where * means cells with expression of both markers.Are those CD4 with CD3 marker...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
...cells (CD3+CD4+ cells) and t suppressor or cytotoxic cells (CD3+CD8+ cells). Thus the 45/62 probably reflects the percentage of lymphocytes that are CD4 and CD3 positive respectively. I am not sure what the 44 stands for. You don't indicate what... Read more »

t-cell percentage

Back in oct.,2004 my t cell count was 319 and the percentage was 14, and my viral load was undetectable,since then my t cell count has gone down to 208,the %is at 17,viral load is still undetectable.I'm concerened that its is the meds not working...
Katherine Luzuriaga, M.D.

Response from Katherine Luzuriaga, M.D.

University of Massachusetts, Medical School
...CD4+ T cells are a type of lymphocyte (white blood cell). To measure the CD4+ T cell count, we measure the percent of T cells that also Read more »
Articles
Treatment Action Group

Dendritic Cells in Drag: Inauspicious Debut for HIV Specific CTLs; New Concerns about IL-12; Neutralizing Approaches for "Bad" Cytokines; Parke-Davis Targets Cellular Factors

...pulmonary edema, a possible consequence of massive lymphocyte expansion andlocalization in the lungs, than IL-2 in mice. Adoptive Cell Transfer Several years back, Dr. Phil Greenberg and colleagues from the University of Washington in Seattle... Read more »
Gay Men's Health Crisis

Stalking HIV Immune Dysregulation

...researchers have raised the possibility that the thymus compensates for T-cell loss by increasing its production of replacement cells, although this theory remains controversial. Part of the difficulty lays in interpreting TREC levels. Since... Read more »
The Body PRO

Elite Controllers May Experience Higher Immune Activation Levels Than Other HIV-Infected Patients, Spurring Concerns of CD4+ Decline

...patients with high levels of T-cell activation tend to progress more rapidly to AIDS and, in the setting of treatment, gain fewer T cells during suppressive antiretroviral therapy. We wondered whether these elite controllers, while exhibiting... Read more »
Treatment Action Group

Mad, Mad Science: Improved Clinical Outcomes Wrought By Immunosuppressive Medicine and Second-Rate Immune Responses - Where Will It All End?

...apoptosis, which was significantly reduced in vitro following 15 days of prednilisone treatment. Whether the apparent rescue of CD4+ T cells from apoptosis alone - or from a combination of activation- and HIV-induced cellular events - effected... Read more »
Connect With Others

What is a T-Cell or CD4 Count?

Posted by TheBody
...What Is a T-Cell or CD4 Count? Your T-cell count, also known as a CD4 count, reveals the number of T cells in your body. A T cell is a special kind of white blood cell, and the more you have, the stronger your immune system is. When Read more »

Read the stories but I think I'm still +

Posted by Anonymous, 5 Replies
I've read all the uplifting stories and still cant stop thinking I'm positive as well as some of my family members. I've posted before so some of you may rememeber. My risk was slight oral exposure (on her) to a stripper that was from Russia. It... Read more »

T-Cell tests

Posted by Anonymous, 2 Replies
...Does anybody know where you can get a T-cell count without going to the doctor? Some places will run a CBC (ehivtest) without a doctor. Will they do T-Cell count as well? Read more »

T-cells dropping..............

Posted by MIT, 3 Replies
...T-cells dropping, viral load still low - under 13000 and feeling uneasy about going on meds. should one consider meds at under 200 or Read more »