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Cell Markers Expressed By Cd4 T Cells

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Get the Facts
The Well Project

Understanding CD4 Cells and CD4 Cell Tests

The Basics CD4 Count and HIV CD4 Count and HIV Treatment CD4 Cell Test The Bottom Line The Basics Your immune system protects your body by fighting germs and infections.White blood cells are an important part of your immune system. HIV infects and destroys a type of white blood cell called aCD4 cell (sometimes called a T-cell). As the immune system loses CD4 cells, it becomes weaker and is less able tofight off germs. When it...
Ask the Experts

Absolute CD4 vs. Percentage CD4 as Marker for Treatment

Dr. Wohl,I have really enjoyed how clear and concise your answers are, and how sensitively and respectfully you present them. Your coining of the term "lemonAIDS" gave me the chuckle I've needed all day.Here's my concern. I...
David Wohl, M.D.

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill
Hi-Thanks for your comments. If I understand you correctly, your CD4 cell count has dropped from 420 to 198 over 3 months but your CD4% has remained about the same. If so, then I agree with your clinician and would not initiate HIV therapy just... Read more »

KS, Chemotherapy and CD4-Cells; How much of a hit will my CD4 cells take if I start chemotherapy?

I was recently told I have KS and am awaiting confirmation by biopsy. My cd4 count is about 200 and I have HEP B working on my liver. The first words out of the dr's mouth was chemo but I question that because of my cd4 count. I have not...
Bruce Dezube, M.D.

Response from Bruce Dezube, M.D.

Harvard Medical School
Although I can appreciate your concern that chemotherapy may suppress your CD4 count, I would like to give you some reassurance. Although I'm not sure what type of chemotherapy your oncologist will recommend, typically we start with liposomal... Read more »


Ok i have this test result in 1999 stating:CD3+CD4+cells 34.1% and expected ratio 42.0-58.0%(663-1477) CD3+CD8+cells 27.2% with expected ratio 22-30.0 % (342-754)CD3+Cells at 67.7% and expected ratio 69.5-81.3%cd4/cd8 ratio=1.33 months ago i...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
You don't indicate what your HIV viral load is or whether you are receiving HIV meds or not.... Read more »

Co-expressing cd4/cd8?

I had a notation on my last set of labs that I'm curious to get your opinion of. It read something like "Unusual staining pattern, .4% of lymphocytes co-expressing cd4 & cd8." Does this indicate anything significant? My total...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
Many papers have been published describing this phenomenon in HIV infection, other infections and malignancies.... Read more »
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What is a T-Cell or CD4 Count?

Posted by TheBody
What Is a T-Cell or CD4 Count?

Your T-cell count, also known as a CD4 count, reveals the number of T cells in your body. A T cell is a special kind of white blood cell, and the more you have, the stronger your immune system is. When you were infected... Read more »

IL-2 Induces Sustained CD4 Cell Increases

Posted by Anonymous, 1 Reply
IL-2 Induces Sustained CD4 Cell Increases in HIV-Infected Patients

By Deborah Mitchell

TORONTO, Sep 20 (Reuters Health) - The addition of recombinant interleukin-2 (IL-2) to an HIV antiretroviral therapy produces an increase in CD4+ T-cell counts,... Read more »

Do anybody know about CD4 cells count?

Posted by Anonymous, 1 Reply
Hi guys,

I have a question about my tests - in fear of HIV infection because of a bad incident and symptoms not long after, I went to have my blood tested for HIV as well as other infections - the PCR and antibody test both turned out Negative, but... Read more »

Use of cd4/cd8

Posted by Anonymous
dropping by this bulletin-board, I see there is a lot of use and abuse of t-cell subsets among worried wells. To put things in perspective - cd4/cd8-ratios were used as a surrogate marker of HIV-infection among blood donors at a US hospital... Read more »