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Cd4 Receptors In Hiv

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Ask the Experts

HIV or Meds causing abnormal CD4 receptors?

Dr. Boyle, Do all HIV positive folk have abnormal CD4 cell receptors? If so, is this caused by HIV infection or is it a side effect of meds? How do these abnormalities manifest themselves...do they cause symptoms or compromise immune...
Brian Boyle, M.D., J.D.

Response from Brian Boyle, M.D., J.D.

Cornell University, Weill Medical College
...Your question is a little confusing, but I'll try to give you the answer your looking for. CD4+ T cell deficits are not present in all patients with HIV, and the time to develop signficanty immunocompromise (low CD4+ T cells) Read more »

CD4 receptors

Dr., is it true that the CD4 receptors of all HIV infected people are abnormal? If so, in which way... Read more »

What is best indicator of hiv progression cd4 or cd4 %

My labs are as followsJune 08- CD4 590 VL 309 CD4% 273 months later- CD4 770 VL 2080 cd4% 263... Read more »
Articles
AIDSinfo

The HIV Life Cycle

...Terms Used in This Fact Sheet CD4 receptor: A protein present on the outside of infection- fighting white blood cells. CD4 receptors allow HIV to bind to and enter cells. Co-receptor: In addition to binding a CD4 receptor, HIV must also... Read more »
Henry J. Kaiser Family Foundation

Studies Examine Use of Modified CD4+ T Cells, Vaccine to Fight HIV/AIDS

...Oxford, England, London's Guardian reports (Randerson, Guardian , 11/10). The therapy involves genetically engineering CD4+ T cells, called "assassin" cells by the researchers, which were able to recognize other cells infected with HIV and... Read more »
The Body PRO

High-Dose Intravenous Immunoglobulin May Reduce Latent HIV Reservoir in Resting CD4+ Cells, Study Suggests

...his explanation, he then answers questions from the audience. Magnus GisslĂ©n: The viral reservoir in latent, HIV-infected CD4+ cells is very stable and has a very long half-life. As yet, no approach to decrease this reservoir has proven... Read more »
The Well Project

HIV Drugs and the HIV Lifecycle

... Binding and Fusion HIV begins to enter a CD4 cell by binding (or attaching) itself to aspecific point, called a CD4 receptor, on the cell's surface. HIV must thenbind to a second co-receptor, either the CCR5 co-receptor or the... Read more »
Connect With Others

Unusual case. Ongoing Low CD4 - HIV possible?

Posted by Tryin2BRational, 4 Replies
...negative/non reactive/undetectable. In June of this year, one of the physicians I was working with ordered - at my urging - a CD4 test because I thought that would give me the peace of mind I needed. Well it didn't. It came back 414 (37%) in... Read more »

HIV postive/cd4 count normal/ vl 37thousand

Posted by jniteowl69, 4 Replies
...have been getting flu like sympthons alot and I have lost over 100 lbs,my lmp.nodes are swallon and I get tired really easy my cd4 is 999 and my vl is in 37 thousand ,is this normal to be getting these sympthons? I Read more »

REVIVO

Posted by Anonymous, 5 Replies
...of desperation when i was diagnosed back in July 2003 and took it (am treatment naive). My VL dropped from 20000 to 3000 and CD4 from 393 to 600 in six weeks! My doctor said it could have been a result of the end of the acute phase of infection.... Read more »

TNX - 355 TRIAL

Posted by Survivor
...viral-entry inhibitors. TNX-355, which is administered intravenously, is distinct from other entry inhibitors in that it binds to CD4 receptors, the primary target of HIV infection. Since TNX-355 blocks HIV entry at a step prior to the... Read more »