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Cd4 Increment For Antiretroviral Takers

Here's a taste of what has to offer on this topic:
Get the Facts
AIDS InfoNet

Fusion and Attachment Inhibitors

...ViiV Healthcare is a new CCR5 antagonist in Phase I trials. HGS004 by Human Genome Sciences, a monoclonal antibody CCR5 blocker, successfully completed a Phase II trial. Ibalizumab (TNX-355) by TaiMed Biologics blocks the CD4 receptor. It is a genetically engineered drug, a "monoclonal antibody." It is being studied as an intravenous infusion every two or four weeks. It is administered along with antiretroviral medications. No...
Ask the Experts

No viral load, no antiretrovirals, low CD4

I have been positive for 22 years ( I am from the time of the "gay cancer"), and have never been sick. I have also never had any kind of medication for HIV. At the moment my CD4s are 170, and my viral load is undectetable. What should I do? Thank you
David Wohl, M.D.

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill
...accomplished. If all else fails, a trial of HIV therapy may not be too absurd. A 6-8 week course, if found to increase you CD4 cells, would suggest that on-going virus replication was contributing to your CD4 decline. Regardless, you should be... Read more »

Viral load 200,000; CD4 380 - - Should I start anti-retroviral treatment?

The details:Got sick late May. Western Blot inconclusive. Sick again early July. Western blot positive. CD4 and viral load test done early July, results: CD4 of 380 and viral load count of 200,000. Test was done at the tail end of the illness I...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
...were obtained during acute HIV infection illness, things may quite down a bit in a month or two (viral load decrease and/or CD4 count increase). I would get another set of numbers before starting treatment. If the numbers are relatively the same,... Read more »

Why CD4 goes down while CD4% goes up (ABSOLUTE CD4 COUNT VERSUS CD4%, 2009)

Hi Dr. Bob, it is a real pleasure to read your answers full of help, professionalism, generosity and fun. I started therapy at an absolute CD4 of 405 and 26% and VL above 100k, I started Atripla six months ago after the first three months my CD4...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
...transient divergence. Nothing is "wrong" and you should not worry about this one test result. You feel great and your combination antiretroviral regimen is performing well! I see nothing but good news! I'll reprint some information from the... Read more »

Absolute CD4 count down while CD4% up. (ABSOLUTE CD4 COUNT VERSUS CD4%)

Hello Dr. Bob,You are wonderful and doing very important job :) . I have never seen such a Doctor who has an excellent sense of humor and plays the piano. Btw, I play the cello :) . Now my question. My time of infection is between 2006 02 and 2006...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
...load? Yes, I feel it is very important, as it is the critical piece of information that allows us to measure how effectively our antiretroviral drugs are performing in suppressing HIV replication. It also alerts us as to when and if drug... Read more »
U.S. Centers for Disease Control and Prevention

Incomplete Peripheral CD4+ Cell Count Restoration in HIV-Infected Patients Receiving Long-Term Antiretroviral Treatment

... In most HIV-positive patients, antiretroviral therapy can fully restore a normal CD4+ cell count of more than 500 cells/mm 3 . However, the researchers note, it is not clear Read more »
The Body PRO

Higher HCV RNA Levels Associated With Greater Early T-Cell Activation and CD4+ Cell Depletion Among Antiretroviral-Naive, HIV/HCV-Coinfected Patients these coinfected women, adjusted for the potential covariates, which are age, HIV RNA load, IV [intravenous] drug use, and antiretroviral therapy. Gerald Pierone: What are some of your recommendations for these women? Roksana Karim: ... Read more »
Henry J. Kaiser Family Foundation

Absolute Count and Percentage of CD4+ Lymphocytes Are Independent Predictors of Disease Progression in HIV-Infected Persons Initiating Highly Active Antiretroviral Therapy

...disease progression during the study. They conducted a multivariable analysis that included age, race, sex, HIV-1 RNA, previous antiretroviral therapy, likely transmission route, prior AIDS-defining events, CD4 count and CD4 percentage. ... Read more »
Henry J. Kaiser Family Foundation

HIV Infection, Antiretroviral Therapy, and CD4 + Cell Count Distributions in African Populations

...said that the study could "substantially improve" the development of health care services, including the need and demand for antiretroviral therapy. They also wrote that clearer data are needed to assess the study model and its theories and to... Read more »
Connect With Others


Posted by Anonymous, 5 Replies
...of desperation when i was diagnosed back in July 2003 and took it (am treatment naive). My VL dropped from 20000 to 3000 and CD4 from 393 to 600 in six weeks! My doctor said it could have been a result of the end of the acute phase of infection.... Read more »


Posted by Survivor
...viral-entry inhibitors. TNX-355, which is administered intravenously, is distinct from other entry inhibitors in that it binds to CD4 receptors, the primary target of HIV infection. Since TNX-355 blocks HIV entry at a step prior to the... Read more »

The Failure of Viral Load Tests

Posted by Anonymous, 2 Replies
... Are We Prescribing HIV Drugs Properly? In cash-starved regions of the world, deciding who should get anti-retroviral drugs for HIV is a tough call. Now it... Read more »

MAC. & low cd-4

Posted by danni, 3 Replies
i am terrified, i just learned that i have mac. my viral load is 87,000, my cd-4; only 14. my doc. did start meds for me, but i can't get past the fear that it's too late. with my blood counts, is mac, a sure death sentence? i appreciate any... Read more »